Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RFX3
  • Mouse genes Rfx3
  • Rat genes Rfx3
  • Zfish genes rfx3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rfx3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Rfx3	IDA		Mouse	MGI:MGI:4941444|PMID:20413507
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q12933	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q8HWS3	Human	PMID:20148032
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q14192	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q13643	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q14192	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q15654	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q12933	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q14192	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q13643	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q14192	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q14192	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RFX3	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rfx3	IPI	UniProtKB:Q8C7R7	Mouse	MGI:MGI:4422104|PMID:20148032
Molecular Function	GO:0043565	sequence-specific DNA binding	Rfx3	IDA		Mouse	PMID:24531968
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	RFX3	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	RFX3	IDA		Human	PMID:20148032
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Rfx3	IDA		Mouse	MGI:MGI:4361058|PMID:19671664
Cellular Component	GO:0000785	chromatin	RFX3	IDA		Human	PMID:20413507
Cellular Component	GO:0000785	chromatin	Rfx3	IDA		Mouse	MGI:MGI:4941444|PMID:20413507
Cellular Component	GO:0005667	transcription regulator complex	Rfx3	IDA		Mouse	MGI:MGI:4941444|PMID:20413507
Biological Process	GO:0048469	cell maturation	Rfx3	IMP		Mouse	MGI:MGI:4941444|PMID:20413507
Biological Process	GO:0060271	cilium assembly	Rfx3	IMP		Mouse	MGI:MGI:4941444|PMID:20413507
Biological Process	GO:0060285	cilium-dependent cell motility	Rfx3	IMP		Mouse	MGI:MGI:4361058|PMID:19671664
Biological Process	GO:0007368	determination of left/right symmetry	Rfx3	IMP	MGI:MGI:3045792	Mouse	PMID:15121860
Biological Process	GO:0006351	DNA-templated transcription	Rfx3	IMP		Mouse	MGI:MGI:4361058|PMID:19671664
Biological Process	GO:0031018	endocrine pancreas development	Rfx3	IMP		Mouse	MGI:MGI:3713191|PMID:17229940
Biological Process	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	Rfx3	IMP		Mouse	MGI:MGI:3041887|PMID:15121860
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	RFX3	IDA		Human	PMID:12411430
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	RFX3	IDA		Human	PMID:20148032
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Rfx3	IDA		Mouse	MGI:MGI:4941444|PMID:20413507
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Rfx3	IMP		Mouse	MGI:MGI:4941444|PMID:20413507
Biological Process	GO:2000078	positive regulation of type B pancreatic cell development	Rfx3	IMP		Mouse	MGI:MGI:4941444|PMID:20413507
Biological Process	GO:0006355	regulation of DNA-templated transcription	Rfx3	IMP		Mouse	MGI:MGI:3041887|PMID:15121860
Biological Process	GO:0006355	regulation of DNA-templated transcription	Rfx3	IMP		Mouse	MGI:MGI:4361058|PMID:19671664
Biological Process	GO:0050796	regulation of insulin secretion	Rfx3	IMP		Mouse	MGI:MGI:3713191|PMID:17229940
Biological Process	GO:0050796	regulation of insulin secretion	Rfx3	IMP		Mouse	MGI:MGI:4941444|PMID:20413507
Biological Process	GO:0072560	type B pancreatic cell maturation	Rfx3	IMP		Mouse	MGI:MGI:4941444|PMID:20413507

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern