Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RGMA
  • Mouse genes Rgma
  • Rat genes Rgma
  • Zfish genes rgma
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rgma

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015026	coreceptor activity	Rgma	IGI	MGI:MGI:88177	Mouse	PMID:15975920
Molecular Function	GO:0015026	coreceptor activity	Rgma	IGI	MGI:MGI:88180	Mouse	PMID:15975920
Molecular Function	GO:0005515	protein binding	RGMA	IPI	UniProtKB:Q9NYB0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	RGMA	IPI	UniProtKB:Q30201	Human	PMID:22728873
Molecular Function	GO:0005515	protein binding	Rgma	IPI	PR:P21275	Mouse	PMID:15975920
Molecular Function	GO:0005515	protein binding	Rgma	IPI	PR:P21274	Mouse	PMID:15975920
Molecular Function	GO:0005102	signaling receptor binding	Rgma	IPI	PR:P97798	Mouse	PMID:26651291
Molecular Function	GO:1990459	transferrin receptor binding	RGMA	IPI	UniProtKB:Q9UP52	Human	PMID:22728873
Cellular Component	GO:0009986	cell surface	Rgma	IDA		Mouse	PMID:14749425
Cellular Component	GO:0005783	endoplasmic reticulum	RGMA	IDA		Human	GO_REF:0000054
Cellular Component	GO:0043005	neuron projection	Rgma	IDA		Rat	PMID:16585268|RGD:9850138
Biological Process	GO:0030509	BMP signaling pathway	Rgma	IGI	MGI:MGI:88177	Mouse	PMID:15975920
Biological Process	GO:0030509	BMP signaling pathway	Rgma	IGI	MGI:MGI:88181	Mouse	PMID:15975920
Biological Process	GO:0000902	cell morphogenesis	rgma	IMP	ZFIN:ZDB-MRPHLNO-110301-10	Zfish	PMID:31399534
Biological Process	GO:0000902	cell morphogenesis	rgma	IMP	ZFIN:ZDB-MRPHLNO-200318-1	Zfish	PMID:31399534
Biological Process	GO:0006509	membrane protein ectodomain proteolysis	Rgma	IDA		Mouse	PMID:26651291
Biological Process	GO:0031293	membrane protein intracellular domain proteolysis	rgma	IMP	ZFIN:ZDB-MRPHLNO-200318-1	Zfish	PMID:31399534
Biological Process	GO:0048681	negative regulation of axon regeneration	Rgma	IMP		Rat	PMID:16585268|RGD:9850138
Biological Process	GO:0048671	negative regulation of collateral sprouting	Rgma	IMP		Rat	PMID:23744345|RGD:9850124
Biological Process	GO:0010977	negative regulation of neuron projection development	Rgma	IGI	MGI:MGI:1096335,MGI:MGI:2443718	Mouse	PMID:26651291
Biological Process	GO:0010977	negative regulation of neuron projection development	Rgma	IGI	MGI:MGI:2443718	Mouse	PMID:26651291
Biological Process	GO:0010977	negative regulation of neuron projection development	Rgma	IMP		Mouse	PMID:26651291
Biological Process	GO:0010977	negative regulation of neuron projection development	Rgma	IDA		Rat	PMID:16585268|RGD:9850138
Biological Process	GO:0010977	negative regulation of neuron projection development	Rgma	IDA		Rat	PMID:21645559|RGD:13703101
Biological Process	GO:1900121	negative regulation of receptor binding	Rgma	IMP		Mouse	PMID:26651291
Biological Process	GO:0001843	neural tube closure	Rgma	IMP	MGI:MGI:3029714	Mouse	PMID:14749425
Biological Process	GO:0031175	neuron projection development	Rgma	IMP		Mouse	PMID:26651291
Biological Process	GO:0043547	positive regulation of GTPase activity	Rgma	IDA		Mouse	PMID:26651291
Biological Process	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	Rgma	IDA		Mouse	PMID:26651291
Biological Process	GO:0010976	positive regulation of neuron projection development	Rgma	IDA		Rat	PMID:18452705|RGD:9850152
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	RGMA	IDA		Human	PMID:22728873
Biological Process	GO:0030510	regulation of BMP signaling pathway	Rgma	IMP		Mouse	PMID:17472960
Biological Process	GO:0030510	regulation of BMP signaling pathway	Rgma	IDA		Mouse	PMID:17472960

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern