Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RGP1
  • Mouse genes Rgp1
  • Rat genes Rgp1
  • Zfish genes rgp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rgp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RGP1	IDA		Human	PMID:23091056
Molecular Function	GO:0005515	protein binding	RGP1	IPI	UniProtKB:P14079	Human	PMID:22458338
Molecular Function	GO:0005515	protein binding	RGP1	IPI	UniProtKB:P20340	Human	PMID:23091056
Molecular Function	GO:0005515	protein binding	RGP1	IPI	UniProtKB:Q4ADV7	Human	PMID:23091056
Molecular Function	GO:0005515	protein binding	RGP1	IPI	UniProtKB:O75679	Human	PMID:32296183
Molecular Function	GO:0031267	small GTPase binding	RGP1	IDA		Human	PMID:23091056
Cellular Component	GO:0005829	cytosol	RGP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	RGP1	IDA		Human	PMID:23091056
Cellular Component	GO:0016020	membrane	RGP1	IDA		Human	PMID:23091056
Cellular Component	GO:0005886	plasma membrane	RGP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	RGP1	IDA		Human	PMID:23091056
Cellular Component	GO:0034066	Ric1-Rgp1 guanyl-nucleotide exchange factor complex	RGP1	IDA		Human	PMID:23091056
Biological Process	GO:0051216	cartilage development	rgp1	IMP	ZFIN:ZDB-CRISPR-200720-2	Zfish	PMID:31932796
Biological Process	GO:0042177	negative regulation of protein catabolic process	RGP1	IMP		Human	PMID:23091056
Biological Process	GO:0043547	positive regulation of GTPase activity	RGP1	IDA		Human	PMID:23091056
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	RGP1	IMP		Human	PMID:23091056

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern