Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RGS10
  • Mouse genes Rgs10
  • Rat genes Rgs10
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rgs10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001965	G-protein alpha-subunit binding	RGS10	IPI	UniProtKB:P08754	Human	PMID:18434541
Molecular Function	GO:0005096	GTPase activator activity	RGS10	IDA		Human	PMID:11443111
Molecular Function	GO:0005096	GTPase activator activity	RGS10	IDA		Human	PMID:18434541
Molecular Function	GO:0005515	protein binding	RGS10	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rgs10	IPI	PR:Q9DBB1	Mouse	PMID:15284227
Cellular Component	GO:0043679	axon terminus	Rgs10	IDA		Rat	PMID:15593368|RGD:2303814
Cellular Component	GO:0005829	cytosol	RGS10	IDA		Human	PMID:11443111
Cellular Component	GO:0043197	dendritic spine	Rgs10	IDA		Rat	PMID:15593368|RGD:2303814
Cellular Component	GO:0043025	neuronal cell body	Rgs10	IDA		Rat	PMID:15593368|RGD:2303814
Cellular Component	GO:0016604	nuclear body	RGS10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	RGS10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RGS10	IDA		Human	PMID:11443111
Cellular Component	GO:0005634	nucleus	RGS10	IDA		Human	PMID:10791963
Cellular Component	GO:0005634	nucleus	Rgs10	IDA		Rat	PMID:15593368|RGD:2303814
Biological Process	GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	RGS10	IDA		Human	PMID:11443111
Biological Process	GO:0043547	positive regulation of GTPase activity	RGS10	IDA		Human	PMID:18434541
Biological Process	GO:0001975	response to amphetamine	Rgs10	IEP		Rat	PMID:26321241|RGD:13524514

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern