Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Rgs14

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes RGS14
- Mouse genes Rgs14
- Rat genes Rgs14
- Zfish genes rgs14a,rgs14b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rgs14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001965	G-protein alpha-subunit binding	Rgs14	IPI	RGD:2714	Rat	PMID:11387333\|RGD:7207387
Molecular Function	GO:0005092	GDP-dissociation inhibitor activity	RGS14	IDA		Human	PMID:15917656
Molecular Function	GO:0005092	GDP-dissociation inhibitor activity	Rgs14	IDA		Rat	PMID:15337739\|RGD:8554224
Molecular Function	GO:0032794	GTPase activating protein binding	Rgs14	IPI	UniProtKB:P18872	Mouse	MGI:MGI:5009199\|PMID:10926822
Molecular Function	GO:0032794	GTPase activating protein binding	Rgs14	IPI	UniProtKB:P10824	Mouse	MGI:MGI:5284776\|PMID:17635935
Molecular Function	GO:0005096	GTPase activator activity	RGS14	IDA		Human	PMID:15917656
Molecular Function	GO:0005096	GTPase activator activity	Rgs14	IDA		Mouse	MGI:MGI:5009199\|PMID:10926822
Molecular Function	GO:0005096	GTPase activator activity	Rgs14	IDA		Rat	PMID:15337739\|RGD:8554224
Molecular Function	GO:0008017	microtubule binding	RGS14	IDA		Human	PMID:15917656
Molecular Function	GO:0005515	protein binding	RGS14	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	RGS14	IPI	UniProtKB:P08754	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	RGS14	IPI	UniProtKB:P08754	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:Q9JM13	Mouse	MGI:MGI:5009199\|PMID:10926822
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:Q80ZJ1	Mouse	MGI:MGI:5009199\|PMID:10926822
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:P04897	Rat	PMID:11387333\|RGD:7207387
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:P08753	Rat	PMID:11387333\|RGD:7207387
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:P10824	Rat	PMID:11387333\|RGD:7207387
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:P08753	Rat	PMID:16870394\|RGD:8553973
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:P10824	Rat	PMID:16870394\|RGD:8553973
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:D3Z8L7	Rat	PMID:19319189\|RGD:8554645
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:P08644	Rat	PMID:19319189\|RGD:8554645
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:P11345	Rat	PMID:19319189\|RGD:8554645
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:P20171	Rat	PMID:19319189\|RGD:8554645
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:P97538	Rat	PMID:19319189\|RGD:8554645
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:Q04970	Rat	PMID:19319189\|RGD:8554645
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:P20171	Rat	PMID:19878719\|RGD:8553779
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:P10824	Rat	PMID:21158412\|RGD:8553612
Molecular Function	GO:0005515	protein binding	Rgs14	IPI	UniProtKB:Q80ZG1	Rat	PMID:21158412\|RGD:8553612
Molecular Function	GO:0019901	protein kinase binding	Rgs14	IPI	UniProtKB:P11345	Rat	PMID:19878719\|RGD:8553779
Molecular Function	GO:0030159	signaling receptor complex adaptor activity	Rgs14	IDA		Rat	PMID:19319189\|RGD:8554645
Cellular Component	GO:0005813	centrosome	Rgs14	IDA		Mouse	MGI:MGI:3513218\|PMID:15525537
Cellular Component	GO:0005813	centrosome	Rgs14	IDA		Mouse	MGI:MGI:5284798\|PMID:15520006
Cellular Component	GO:0005813	centrosome	Rgs14	IDA		Rat	PMID:16870394\|RGD:8553973
Cellular Component	GO:0005737	cytoplasm	Rgs14	IDA		Mouse	MGI:MGI:5009199\|PMID:10926822
Cellular Component	GO:0005737	cytoplasm	Rgs14	IDA		Mouse	MGI:MGI:3513218\|PMID:15525537
Cellular Component	GO:0005737	cytoplasm	Rgs14	IDA		Mouse	MGI:MGI:5284798\|PMID:15520006
Cellular Component	GO:0005737	cytoplasm	Rgs14	IDA		Rat	PMID:16819986\|RGD:7207381
Cellular Component	GO:0005737	cytoplasm	Rgs14	IDA		Rat	PMID:16870394\|RGD:8553973
Cellular Component	GO:0005737	cytoplasm	Rgs14	IDA		Rat	PMID:19878719\|RGD:8553779
Cellular Component	GO:0005737	cytoplasm	Rgs14	IDA		Rat	PMID:21158412\|RGD:8553612
Cellular Component	GO:0030425	dendrite	Rgs14	IDA		Mouse	MGI:MGI:4834960\|PMID:20837545
Cellular Component	GO:0030425	dendrite	Rgs14	IDA		Rat	PMID:16819986\|RGD:7207381
Cellular Component	GO:0043197	dendritic spine	Rgs14	IDA		Mouse	MGI:MGI:4834960\|PMID:20837545
Cellular Component	GO:0098978	glutamatergic synapse	Rgs14	IMP		Mouse	PMID:28776200
Cellular Component	GO:0098978	glutamatergic synapse	Rgs14	IDA		Mouse	PMID:28776200
Cellular Component	GO:0098978	glutamatergic synapse	Rgs14	IDA		Mouse	PMID:20837545
Cellular Component	GO:0016604	nuclear body	Rgs14	IDA		Mouse	MGI:MGI:5284798\|PMID:15520006
Cellular Component	GO:0005634	nucleus	Rgs14	IDA		Mouse	MGI:MGI:5284798\|PMID:15520006
Cellular Component	GO:0005634	nucleus	Rgs14	IDA		Mouse	PMID:15525537
Cellular Component	GO:0005634	nucleus	Rgs14	IDA		Rat	PMID:16870394\|RGD:8553973
Cellular Component	GO:0005886	plasma membrane	Rgs14	IDA		Mouse	MGI:MGI:5009199\|PMID:10926822
Cellular Component	GO:0005886	plasma membrane	Rgs14	IDA		Rat	PMID:16870394\|RGD:8553973
Cellular Component	GO:0005886	plasma membrane	Rgs14	IDA		Rat	PMID:21158412\|RGD:8553612
Cellular Component	GO:0014069	postsynaptic density	Rgs14	IDA		Mouse	PMID:20837545
Cellular Component	GO:0005819	spindle	RGS14	IDA		Human	PMID:15917656
Cellular Component	GO:0005819	spindle	Rgs14	IDA		Mouse	MGI:MGI:5284793\|PMID:15917656
Cellular Component	GO:0005819	spindle	Rgs14	IDA		Mouse	PMID:15525537
Cellular Component	GO:0000922	spindle pole	Rgs14	IDA		Rat	PMID:16870394\|RGD:8553973
Biological Process	GO:0051301	cell division	RGS14	IMP		Human	PMID:17635935
Biological Process	GO:0007059	chromosome segregation	Rgs14	IMP		Mouse	MGI:MGI:3513218\|PMID:15525537
Biological Process	GO:0008354	germ cell migration	rgs14a	IMP	ZFIN:ZDB-MRPHLNO-141031-3	Zfish	PMID:25049415
Biological Process	GO:0007612	learning	Rgs14	IMP		Mouse	MGI:MGI:4834960\|PMID:20837545
Biological Process	GO:0007616	long-term memory	Rgs14	IMP		Mouse	MGI:MGI:4834960\|PMID:20837545
Biological Process	GO:0060291	long-term synaptic potentiation	Rgs14	IDA		Mouse	MGI:MGI:4834960\|PMID:20837545
Biological Process	GO:0000278	mitotic cell cycle	Rgs14	IMP	MGI:MGI:3514019	Mouse	PMID:15525537
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Rgs14	IDA		Mouse	PMID:28776200
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Rgs14	IMP		Mouse	PMID:28776200
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Rgs14	IDA		Rat	PMID:19878719\|RGD:8553779
Biological Process	GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	Rgs14	IDA		Mouse	MGI:MGI:5009199\|PMID:10926822
Biological Process	GO:0043407	negative regulation of MAP kinase activity	Rgs14	IMP		Mouse	MGI:MGI:4834960\|PMID:20837545
Biological Process	GO:0031914	negative regulation of synaptic plasticity	Rgs14	IMP		Mouse	MGI:MGI:4834960\|PMID:20837545
Biological Process	GO:0006913	nucleocytoplasmic transport	Rgs14	IDA		Mouse	MGI:MGI:5284798\|PMID:15520006
Biological Process	GO:0006913	nucleocytoplasmic transport	Rgs14	IDA		Rat	PMID:16870394\|RGD:8553973
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	Rgs14	IDA		Rat	PMID:19878719\|RGD:8553779
Biological Process	GO:0043547	positive regulation of GTPase activity	Rgs14	IDA		Mouse	MGI:MGI:5009199\|PMID:10926822
Biological Process	GO:0050769	positive regulation of neurogenesis	Rgs14	IMP		Rat	PMID:19319189\|RGD:8554645
Biological Process	GO:0043620	regulation of DNA-templated transcription in response to stress	Rgs14	IDA		Mouse	MGI:MGI:5284798\|PMID:15520006
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	Rgs14	IDA		Rat	PMID:11976690\|RGD:729762
Biological Process	GO:0006979	response to oxidative stress	Rgs14	IMP		Rat	PMID:21255223\|RGD:8553870
Biological Process	GO:0007051	spindle organization	RGS14	IMP		Human	PMID:15917656
Biological Process	GO:0007051	spindle organization	Rgs14	IMP		Mouse	MGI:MGI:3513218\|PMID:15525537
Biological Process	GO:0008542	visual learning	Rgs14	IMP		Rat	PMID:19574389\|RGD:8553361
Biological Process	GO:0010070	zygote asymmetric cell division	Rgs14	IMP		Mouse	MGI:MGI:3513218\|PMID:15525537

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.