Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RHOB
  • Mouse genes Rhob
  • Rat genes Rhob
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rhob

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	Rhob	IDA		Mouse	PMID:8939998
Molecular Function	GO:0005515	protein binding	RHOB	IPI	UniProtKB:Q13829	Human	PMID:19637314
Molecular Function	GO:0005515	protein binding	RHOB	IPI	UniProtKB:Q9HCE7-2	Human	PMID:25249323
Molecular Function	GO:0005515	protein binding	RHOB	IPI	UniProtKB:Q6ZS17	Human	PMID:27807006
Molecular Function	GO:0005515	protein binding	Rhob	IPI	PR:Q62160	Mouse	PMID:8939998
Molecular Function	GO:0005515	protein binding	Rhob	IPI	PR:P49025	Mouse	PMID:8543060
Cellular Component	GO:0032154	cleavage furrow	RHOB	IDA		Human	PMID:16236794
Cellular Component	GO:0005829	cytosol	Rhob	IDA		Rat	PMID:21440892|RGD:7248703
Cellular Component	GO:0005769	early endosome	Rhob	IDA		Mouse	PMID:17623777
Cellular Component	GO:0010008	endosome membrane	RHOB	IDA		Human	PMID:15226397
Cellular Component	GO:0010008	endosome membrane	RHOB	IDA		Human	PMID:19637314
Cellular Component	GO:0070062	extracellular exosome	RHOB	HDA		Human	PMID:19056867
Cellular Component	GO:0005925	focal adhesion	RHOB	HDA		Human	PMID:21423176
Cellular Component	GO:0005770	late endosome	Rhob	IDA		Mouse	PMID:17623777
Cellular Component	GO:0016020	membrane	Rhob	IDA		Mouse	PMID:8939998
Cellular Component	GO:0016020	membrane	Rhob	IDA		Rat	PMID:21440892|RGD:7248703
Cellular Component	GO:0005634	nucleus	Rhob	IDA		Mouse	MGI:MGI:2679407|PMID:14597666
Cellular Component	GO:0005886	plasma membrane	RHOB	IDA		Human	PMID:15226397
Cellular Component	GO:0005886	plasma membrane	RHOB	IDA		Human	PMID:19637314
Cellular Component	GO:0005886	plasma membrane	Rhob	IDA		Mouse	PMID:15093731
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Rhob	IDA		Mouse	PMID:20203211
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Rhob	IMP		Mouse	PMID:20203211
Cellular Component	GO:0045202	synapse	Rhob	IDA		Rat	PMID:10713089|RGD:155230718
Biological Process	GO:0007155	cell adhesion	Rhob	IDA		Mouse	MGI:MGI:2150450|PMID:11564874
Biological Process	GO:0070301	cellular response to hydrogen peroxide	RHOB	IDA		Human	PMID:21373644
Biological Process	GO:0071479	cellular response to ionizing radiation	RHOB	IDA		Human	PMID:21373644
Biological Process	GO:0008333	endosome to lysosome transport	RHOB	IDA		Human	PMID:10508588
Biological Process	GO:0061154	endothelial tube morphogenesis	RHOB	IMP		Human	PMID:21347332
Biological Process	GO:0006886	intracellular protein transport	Rhob	IMP		Mouse	PMID:17623777
Biological Process	GO:0000281	mitotic cytokinesis	RHOB	IMP		Human	PMID:16236794
Biological Process	GO:0045786	negative regulation of cell cycle	Rhob	IMP		Mouse	MGI:MGI:2150450|PMID:11564874
Biological Process	GO:0030336	negative regulation of cell migration	RHOB	IDA		Human	PMID:20460403
Biological Process	GO:0045766	positive regulation of angiogenesis	Rhob	IMP		Mouse	MGI:MGI:2679407|PMID:14597666
Biological Process	GO:0043065	positive regulation of apoptotic process	RHOB	IMP		Human	PMID:21373644
Biological Process	GO:0043065	positive regulation of apoptotic process	Rhob	IDA		Mouse	MGI:MGI:3688063|PMID:11353846
Biological Process	GO:0010595	positive regulation of endothelial cell migration	RHOB	IMP		Human	PMID:21347332
Biological Process	GO:0030334	regulation of cell migration	RHOB	IGI	RNAcentral:URS000039ED8D_9606	Human	PMID:20460403
Biological Process	GO:0099159	regulation of modification of postsynaptic structure	Rhob	IDA		Mouse	PMID:20203211
Biological Process	GO:0099159	regulation of modification of postsynaptic structure	Rhob	IMP		Mouse	PMID:20203211

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern