Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RHOC
  • Mouse genes Rhoc
  • Rat genes Rhoc
  • Zfish genes rhoca,rhocb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rhoc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RHOC	IPI	UniProtKB:Q16513	Human	PMID:20974804
Molecular Function	GO:0005515	protein binding	RHOC	IPI	UniProtKB:Q9Y4F9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RHOC	IPI	UniProtKB:Q6ZS17	Human	PMID:27807006
Molecular Function	GO:0005515	protein binding	RHOC	IPI	UniProtKB:Q96MK2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rhoc	IPI	UniProtKB:Q80U16	Mouse	MGI:MGI:5789047|PMID:27269051
Molecular Function	GO:0005515	protein binding	Rhoc	IPI	PR:P49025	Mouse	PMID:8543060
Molecular Function	GO:0005515	protein binding	Rhoc	IPI	MGI:MGI:96932	Mouse	PMID:8464478
Molecular Function	GO:0005515	protein binding	Rhoc	IPI	PR:Q07139	Mouse	PMID:8464478
Cellular Component	GO:0032154	cleavage furrow	RHOC	IDA		Human	PMID:16236794
Cellular Component	GO:0005829	cytosol	Rhoc	IDA		Rat	PMID:21440892|RGD:7248703
Cellular Component	GO:0070062	extracellular exosome	RHOC	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	RHOC	HDA		Human	PMID:19199708
Cellular Component	GO:0016020	membrane	Rhoc	IDA		Rat	PMID:21440892|RGD:7248703
Cellular Component	GO:0005634	nucleus	Rhoc	IDA		Mouse	PMID:15093731
Cellular Component	GO:0005886	plasma membrane	Rhoc	IDA		Mouse	PMID:15093731
Cellular Component	GO:0032420	stereocilium	Rhoc	IDA		Mouse	MGI:MGI:5789047|PMID:27269051
Biological Process	GO:0043297	apical junction assembly	RHOC	IDA		Human	PMID:20974804
Biological Process	GO:0043297	apical junction assembly	Rhoc	IDA		Mouse	MGI:MGI:4941685|PMID:20974804
Biological Process	GO:0000281	mitotic cytokinesis	RHOC	IDA		Human	PMID:16236794
Biological Process	GO:0030335	positive regulation of cell migration	RHOC	IMP		Human	PMID:20232393
Biological Process	GO:0030335	positive regulation of cell migration	RHOC	IMP		Human	PMID:22057916
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	RHOC	HMP		Human	PMID:12761501
Biological Process	GO:0060193	positive regulation of lipase activity	RHOC	IDA		Human	PMID:19887681
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	Rhoc	IMP		Mouse	MGI:MGI:5789047|PMID:27269051
Biological Process	GO:0051496	positive regulation of stress fiber assembly	RHOC	IMP		Human	PMID:20232393

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern