Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RHOQ
  • Mouse genes Rhoq
  • Rat genes Rhoq
  • Zfish genes rhoq
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rhoq

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032427	GBD domain binding	RHOQ	IPI	UniProtKB:Q61036	Human	PMID:10445846
Molecular Function	GO:0003924	GTPase activity	RHOQ	IDA		Human	PMID:10445846
Molecular Function	GO:0005522	profilin binding	RHOQ	IPI	UniProtKB:P62962	Human	PMID:10445846
Molecular Function	GO:0005515	protein binding	RHOQ	IPI	UniProtKB:Q8N9N5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RHOQ	IPI	UniProtKB:Q8NDC4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RHOQ	IPI	UniProtKB:Q8TAU3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RHOQ	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RHOQ	IPI	UniProtKB:Q9BYG5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rhoq	IPI	UniProtKB:Q8BH60	Mouse	MGI:MGI:2148898|PMID:11162552
Molecular Function	GO:0005515	protein binding	Rhoq	IPI	PR:Q91W92	Mouse	PMID:10490598
Molecular Function	GO:0005515	protein binding	Rhoq	IPI	PR:Q9CQC5	Mouse	PMID:10490598
Molecular Function	GO:0005515	protein binding	Rhoq	IPI	PR:Q9JM96	Mouse	PMID:10490598
Cellular Component	GO:0005884	actin filament	RHOQ	IDA		Human	PMID:10445846
Cellular Component	GO:0070062	extracellular exosome	RHOQ	HDA		Human	PMID:23533145
Cellular Component	GO:0045121	membrane raft	Rhoq	IDA		Mouse	MGI:MGI:2178001|PMID:11821390
Cellular Component	GO:0005886	plasma membrane	RHOQ	IDA		Human	PMID:10445846
Cellular Component	GO:0005886	plasma membrane	Rhoq	IDA		Rat	PMID:16423627|RGD:11576322
Biological Process	GO:0032869	cellular response to insulin stimulus	RHOQ	IMP		Human	PMID:11309621
Biological Process	GO:0032869	cellular response to insulin stimulus	Rhoq	IMP		Mouse	MGI:MGI:2178001|PMID:11821390
Biological Process	GO:0030866	cortical actin cytoskeleton organization	RHOQ	IMP		Human	PMID:11821390
Biological Process	GO:0030866	cortical actin cytoskeleton organization	Rhoq	IMP		Mouse	MGI:MGI:2178001|PMID:11821390
Biological Process	GO:0046039	GTP metabolic process	RHOQ	IDA		Human	PMID:10445846
Biological Process	GO:0008286	insulin receptor signaling pathway	RHOQ	IMP		Human	PMID:11309621
Biological Process	GO:1903077	negative regulation of protein localization to plasma membrane	RHOQ	IMP		Human	PMID:11309621
Biological Process	GO:1903077	negative regulation of protein localization to plasma membrane	Rhoq	IDA		Mouse	MGI:MGI:2178001|PMID:11821390
Biological Process	GO:0051491	positive regulation of filopodium assembly	RHOQ	IDA		Human	PMID:10445846
Biological Process	GO:0046326	positive regulation of glucose import	RHOQ	IMP		Human	PMID:11309621
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	RHOQ	IDA		Human	PMID:10445846
Biological Process	GO:0008360	regulation of cell shape	Rhoq	IDA		Mouse	PMID:10967094

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern