Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RIC8A
  • Mouse genes Ric8a
  • Rat genes Ric8a
  • Zfish genes ric8a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ric8a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001965	G-protein alpha-subunit binding	Ric8a	IDA		Rat	PMID:12509430|RGD:633903
Molecular Function	GO:0001965	G-protein alpha-subunit binding	Ric8a	IPI	RGD:2713|RGD:620243|RGD:2714|RGD:1310221|RGD:628732|RGD:620770	Rat	PMID:12509430|RGD:633903
Molecular Function	GO:0005096	GTPase activator activity	Ric8a	IDA		Rat	PMID:12509430|RGD:633903
Molecular Function	GO:0005096	GTPase activator activity	Ric8a	IDA		Rat	PMID:21158412|RGD:8553612
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Ric8a	IDA		Rat	PMID:12509430|RGD:633903
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Ric8a	IDA		Rat	PMID:21158412|RGD:8553612
Molecular Function	GO:0005515	protein binding	RIC8A	IPI	UniProtKB:Q9UMX0	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	RIC8A	IPI	UniProtKB:Q9UMX0	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	RIC8A	IPI	UniProtKB:Q9UMX0	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	RIC8A	IPI	UniProtKB:Q9UMX0	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	Ric8a	IPI	PR:P84309	Mouse	PMID:17593019
Molecular Function	GO:0005515	protein binding	Ric8a	IPI	UniProtKB:O08773	Rat	PMID:21158412|RGD:8553612
Molecular Function	GO:0005515	protein binding	Ric8a	IPI	UniProtKB:P10824	Rat	PMID:21158412|RGD:8553612
Cellular Component	GO:0005737	cytoplasm	Ric8a	IDA		Rat	PMID:21158412|RGD:8553612
Cellular Component	GO:0016020	membrane	Ric8a	IDA		Mouse	PMID:17593019
Cellular Component	GO:0005886	plasma membrane	Ric8a	IDA		Rat	PMID:21158412|RGD:8553612
Biological Process	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	Ric8a	IDA		Mouse	PMID:17593019
Biological Process	GO:0071711	basement membrane organization	Ric8a	IMP	MGI:MGI:3608888	Mouse	PMID:21069829
Biological Process	GO:0042074	cell migration involved in gastrulation	Ric8a	IMP	MGI:MGI:3608888	Mouse	PMID:21069829
Biological Process	GO:0070586	cell-cell adhesion involved in gastrulation	Ric8a	IMP	MGI:MGI:3608888	Mouse	PMID:21069829
Biological Process	GO:0007369	gastrulation	Ric8a	IMP	MGI:MGI:3608888	Mouse	PMID:21069829
Biological Process	GO:0001701	in utero embryonic development	Ric8a	IMP	MGI:MGI:3608888	Mouse	PMID:16221497
Biological Process	GO:0009416	response to light stimulus	Ric8a	IMP	MGI:MGI:3608888	Mouse	PMID:16221497
Biological Process	GO:0001944	vasculature development	Ric8a	IMP	MGI:MGI:3608888	Mouse	PMID:21069829
Biological Process	GO:0008542	visual learning	Ric8a	IMP	MGI:MGI:3608888	Mouse	PMID:16221497

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern