Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RICTOR
  • Mouse genes Rictor
  • Rat genes Rictor
  • Zfish genes rictora,rictorb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rictor

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0060090	molecular adaptor activity	RICTOR	IDA		Human	PMID:29567957
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:15467718
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:17461779
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:17565979
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:Q8TCU6	Human	PMID:17565979
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:18339839
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:Q13418	Human	PMID:18339839
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:18566587
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:19446321
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:19875983
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:21045808
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:Q8TCU6	Human	PMID:21339740
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:21376236
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:Q6MZQ0	Human	PMID:21964062
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:22307628
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:23263282
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:23953116
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:24036451
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345,UniProtKB:Q9Y4R8	Human	PMID:24036451
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:Q9BVC4	Human	PMID:24036451
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:24375676
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:Q969H0-2	Human	PMID:25897075
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:27043084
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345,UniProtKB:Q9BPZ7	Human	PMID:29567957
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:Q9Y2K2	Human	PMID:30232230
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P55160	Human	PMID:32647003
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:P42345	Human	PMID:33378666
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:Q93008	Human	PMID:33378666
Molecular Function	GO:0005515	protein binding	RICTOR	IPI	UniProtKB:Q9BPZ7	Human	PMID:33378666
Molecular Function	GO:0005515	protein binding	Rictor	IPI	UniProtKB:Q9JLN9	Mouse	MGI:MGI:5314595|PMID:22307628
Molecular Function	GO:0005515	protein binding	Rictor	IPI	UniProtKB:Q9JLN9	Mouse	MGI:MGI:3801355|PMID:18566586
Molecular Function	GO:0005515	protein binding	Rictor	IPI	UniProtKB:Q9CYP7	Mouse	MGI:MGI:5779633|PMID:25377878
Molecular Function	GO:0005515	protein binding	Rictor	IPI	UniProtKB:Q9JLN9	Mouse	MGI:MGI:3810855|PMID:18664580
Molecular Function	GO:0005515	protein binding	Rictor	IPI	UniProtKB:Q9JLN9	Mouse	MGI:MGI:4830417|PMID:20801936
Molecular Function	GO:0005515	protein binding	Rictor	IPI	UniProtKB:Q9JLN9	Mouse	MGI:MGI:4867369|PMID:21045808
Molecular Function	GO:0005515	protein binding	Rictor	IPI	UniProtKB:P61255|UniProtKB:P62751|UniProtKB:P62754|UniProtKB:Q9JLN9	Mouse	MGI:MGI:4867369|PMID:21045808
Molecular Function	GO:0005515	protein binding	Rictor	IPI	PR:Q8BKH7	Mouse	PMID:21413931
Molecular Function	GO:0019901	protein kinase binding	RICTOR	IPI	UniProtKB:Q9BXM7	Human	PMID:21177249
Molecular Function	GO:0019901	protein kinase binding	RICTOR	IPI	UniProtKB:P49840	Human	PMID:25897075
Molecular Function	GO:0019901	protein kinase binding	RICTOR	IPI	UniProtKB:P49841	Human	PMID:25897075
Molecular Function	GO:0043539	protein serine/threonine kinase activator activity	RICTOR	IDA		Human	PMID:16221682
Molecular Function	GO:0043022	ribosome binding	Rictor	IDA		Mouse	MGI:MGI:4867369|PMID:21045808
Cellular Component	GO:0031932	TORC2 complex	RICTOR	IPI		Human	PMID:17461779
Cellular Component	GO:0031932	TORC2 complex	RICTOR	IDA		Human	PMID:15268862
Cellular Component	GO:0031932	TORC2 complex	RICTOR	IDA		Human	PMID:15467718
Cellular Component	GO:0031932	TORC2 complex	RICTOR	IDA		Human	PMID:24036451
Cellular Component	GO:0031932	TORC2 complex	Rictor	IDA		Mouse	MGI:MGI:3759333|PMID:16962653
Biological Process	GO:0031532	actin cytoskeleton reorganization	RICTOR	IMP		Human	PMID:15268862
Biological Process	GO:0009792	embryo development ending in birth or egg hatching	Rictor	IMP		Mouse	MGI:MGI:3702793|PMID:16962829
Biological Process	GO:0018105	peptidyl-serine phosphorylation	RICTOR	IGI	UniProtKB:Q9BXM7	Human	PMID:21177249
Biological Process	GO:0016310	phosphorylation	RICTOR	IDA		Human	PMID:29567957
Biological Process	GO:0030838	positive regulation of actin filament polymerization	Rictor	IMP		Mouse	PMID:15467718
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	Rictor	IMP		Rat	PMID:17110594|RGD:2307383
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Rictor	IMP		Mouse	PMID:15467718
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	Rictor	IMP		Rat	PMID:17110594|RGD:2307383
Biological Process	GO:0032008	positive regulation of TOR signaling	RICTOR	IMP		Human	PMID:15467718
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	RICTOR	IMP		Human	PMID:15467718
Biological Process	GO:2000114	regulation of establishment of cell polarity	Rictor	IMP	MGI:MGI:3703321	Mouse	PMID:24740015
Biological Process	GO:0010468	regulation of gene expression	Rictor	IMP	MGI:MGI:3703321	Mouse	PMID:24740015
Biological Process	GO:0043087	regulation of GTPase activity	Rictor	IMP		Mouse	PMID:15467718
Biological Process	GO:0050727	regulation of inflammatory response	Rictor	IMP	MGI:MGI:3703321	Mouse	PMID:24740015
Biological Process	GO:0033135	regulation of peptidyl-serine phosphorylation	Rictor	IMP		Mouse	PMID:24740015
Biological Process	GO:0042325	regulation of phosphorylation	Rictor	IMP		Rat	PMID:17110594|RGD:2307383
Biological Process	GO:0051896	regulation of protein kinase B signaling	RICTOR	IDA		Human	PMID:15718470
Biological Process	GO:0051896	regulation of protein kinase B signaling	Rictor	IDA		Mouse	MGI:MGI:3702793|PMID:16962829
Biological Process	GO:0001932	regulation of protein phosphorylation	Rictor	IMP		Mouse	MGI:MGI:5619445|PMID:23092880
Biological Process	GO:0038203	TORC2 signaling	RICTOR	IDA		Human	PMID:16221682

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern