Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Rims1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes RIMS1
- Mouse genes Rims1
- Rat genes Rims1
- Zfish genes rims1a,rims1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rims1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RIMS1	IPI	UniProtKB:P60880	Human	PMID:11438518
Molecular Function	GO:0005515	protein binding	RIMS1	IPI	UniProtKB:Q00975	Human	PMID:11438518
Molecular Function	GO:0005515	protein binding	RIMS1	IPI	UniProtKB:Q13795	Human	PMID:11438518
Molecular Function	GO:0005515	protein binding	RIMS1	IPI	UniProtKB:Q13936	Human	PMID:11438518
Molecular Function	GO:0005515	protein binding	RIMS1	IPI	UniProtKB:Q8WZA2	Human	PMID:11438518
Molecular Function	GO:0005515	protein binding	RIMS1	IPI	UniProtKB:P00519	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	Rims1	IPI	UniProtKB:Q9CZV8	Mouse	MGI:MGI:3765255\|PMID:17803915
Molecular Function	GO:0005515	protein binding	Rims1	IPI	PR:Q9CZT8	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rims1	IPI	PR:P61027	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rims1	IPI	PR:P62823	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rims1	IPI	PR:Q9QYX7	Mouse	PMID:19812333
Molecular Function	GO:0005515	protein binding	Rims1	IPI	PR:P35276	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rims1	IPI	PR:Q504M8	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rims1	IPI	PR:Q69ZP3	Mouse	PMID:25730884
Molecular Function	GO:0005515	protein binding	Rims1	IPI	PR:Q9JKM7	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rims1	IPI	UniProtKB:Q62768	Rat	PMID:11343654\|RGD:634478
Molecular Function	GO:0005515	protein binding	Rims1	IPI	UniProtKB:Q62769	Rat	PMID:11343654\|RGD:634478
Molecular Function	GO:0005515	protein binding	Rims1	IPI	RGD:620054	Rat	PMID:11797009\|RGD:633666
Molecular Function	GO:0005515	protein binding	Rims1	IPI	RGD:708372	Rat	PMID:12163476\|RGD:1299401
Molecular Function	GO:0005515	protein binding	Rims1	IPI	UniProtKB:Q8K3M6	Rat	PMID:12163476\|RGD:1299401
Molecular Function	GO:0005515	protein binding	Rims1	IPI	UniProtKB:Q811U3	Rat	PMID:12391317\|RGD:632516
Molecular Function	GO:0005515	protein binding	Rims1	IPI	RGD:69331	Rat	PMID:12629171\|RGD:152995492
Molecular Function	GO:0005515	protein binding	Rims1	IPI	UniProtKB:Q811U3	Rat	PMID:16095618\|RGD:8553467
Molecular Function	GO:0005515	protein binding	Rims1	IPI	UniProtKB:O70368	Rat	PMID:21241895\|RGD:8554827
Molecular Function	GO:0005515	protein binding	Rims1	IPI	UniProtKB:O89089	Rat	PMID:21241895\|RGD:8554827
Molecular Function	GO:0005515	protein binding	Rims1	IPI	UniProtKB:P54282	Rat	PMID:21241895\|RGD:8554827
Molecular Function	GO:0005515	protein binding	Rims1	IPI	UniProtKB:Q811U3	Rat	PMID:21241895\|RGD:8554827
Molecular Function	GO:0005515	protein binding	Rims1	IPI	UniProtKB:Q62769-1	Rat	PMID:21262469\|RGD:10047275
Molecular Function	GO:0019901	protein kinase binding	Rims1	IPI	UniProtKB:B2DD29	Rat	PMID:16630837\|RGD:8553864
Molecular Function	GO:0003723	RNA binding	RIMS1	HDA		Human	PMID:22658674
Molecular Function	GO:0017124	SH3 domain binding	Rims1	IPI	RGD:708533	Rat	PMID:10748113\|RGD:633421
Molecular Function	GO:0031267	small GTPase binding	Rims1	IPI	UniProtKB:P63011	Rat	PMID:16782817\|RGD:10047238
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Rims1	IDA		Mouse	PMID:27537483
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Rims1	IMP		Mouse	PMID:27537483
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Rims1	IEP		Mouse	PMID:27537483
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Rims1	IDA		Mouse	PMID:21241895
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Rims1	IMP		Mouse	PMID:21241895
Molecular Function	GO:0044325	transmembrane transporter binding	Rims1	IDA		Mouse	PMID:20452978
Cellular Component	GO:0098891	extrinsic component of presynaptic active zone membrane	Rims1	IDA		Mouse	PMID:29606581
Cellular Component	GO:0098891	extrinsic component of presynaptic active zone membrane	Rims1	IMP		Mouse	PMID:29606581
Cellular Component	GO:0098982	GABA-ergic synapse	Rims1	IMP		Mouse	PMID:22753485
Cellular Component	GO:0098982	GABA-ergic synapse	Rims1	IDA		Mouse	PMID:22753485
Cellular Component	GO:0098982	GABA-ergic synapse	Rims1	IDA		Mouse	PMID:29606581
Cellular Component	GO:0098982	GABA-ergic synapse	Rims1	IMP		Mouse	PMID:29606581
Cellular Component	GO:0098982	GABA-ergic synapse	Rims1	IDA		Mouse	PMID:21262469
Cellular Component	GO:0098982	GABA-ergic synapse	Rims1	IMP		Mouse	PMID:21262469
Cellular Component	GO:0098978	glutamatergic synapse	Rims1	IDA		Mouse	PMID:21262469
Cellular Component	GO:0098978	glutamatergic synapse	Rims1	IMP		Mouse	PMID:21262469
Cellular Component	GO:0098978	glutamatergic synapse	Rims1	IDA		Rat	PMID:27462810\|RGD:13702367
Cellular Component	GO:0060077	inhibitory synapse	Rims1	IMP		Mouse	MGI:MGI:5432438\|PMID:22753485
Cellular Component	GO:0005886	plasma membrane	Rims1	IGI	UniProtKB:Q62769-1	Rat	PMID:21262469\|RGD:10047275
Cellular Component	GO:0014069	postsynaptic density	Rims1	IDA		Mouse	PMID:17114649
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Rims1	IDA		Mouse	MGI:MGI:5816444\|PMID:21144999
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Rims1	IDA		Mouse	PMID:27537483
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Rims1	IMP		Mouse	PMID:27537483
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Rims1	IDA		Rat	PMID:27462810\|RGD:13702367
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Rims1	IDA		Rat	PMID:9252191\|RGD:633897
Cellular Component	GO:0042734	presynaptic membrane	Rims1	IDA		Rat	PMID:9252191\|RGD:633897
Cellular Component	GO:0045202	synapse	Rims1	IDA		Mouse	PMID:19812333
Cellular Component	GO:0031982	vesicle	Rims1	IDA		Mouse	MGI:MGI:3821631\|PMID:19036990
Biological Process	GO:0060478	acrosomal vesicle exocytosis	RIMS1	IDA		Human	PMID:22248876
Biological Process	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	Rims1	IGI	MGI:MGI:2152972	Mouse	PMID:17124501
Biological Process	GO:0060291	long-term synaptic potentiation	Rims1	IMP		Rat	PMID:21849565\|RGD:5686386
Biological Process	GO:0007269	neurotransmitter secretion	Rims1	IGI	MGI:MGI:1930773	Mouse	PMID:25730884
Biological Process	GO:1903861	positive regulation of dendrite extension	RIMS1	IDA		Human	PMID:23999003
Biological Process	GO:2000463	positive regulation of excitatory postsynaptic potential	Rims1	IGI	UniProtKB:Q99NE5\|UniProtKB:Q9EQZ7	Mouse	MGI:MGI:4887275\|PMID:21262469
Biological Process	GO:0010628	positive regulation of gene expression	Rims1	IGI	UniProtKB:Q9EQZ7	Mouse	MGI:MGI:4887275\|PMID:21262469
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	Rims1	IGI	UniProtKB:Q99NE5\|UniProtKB:Q9EQZ7	Mouse	MGI:MGI:4887275\|PMID:21262469
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	Rims1	IGI	UniProtKB:Q99NE5\|UniProtKB:Q9EQZ7	Rat	PMID:21262469\|RGD:10047275
Biological Process	GO:0010808	positive regulation of synaptic vesicle priming	Rims1	IGI	UniProtKB:Q99NE5\|UniProtKB:Q9EQZ7\|UniProtKB:Q9Z1N9	Rat	PMID:21262469\|RGD:10047275
Biological Process	GO:0099525	presynaptic dense core vesicle exocytosis	Rims1	IDA		Mouse	PMID:31679900
Biological Process	GO:0099525	presynaptic dense core vesicle exocytosis	Rims1	IMP		Mouse	PMID:31679900
Biological Process	GO:0065003	protein-containing complex assembly	RIMS1	IDA		Human	PMID:11438518
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	Rims1	IDA		Mouse	PMID:21241895
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	Rims1	IMP		Mouse	PMID:21241895
Biological Process	GO:0048169	regulation of long-term neuronal synaptic plasticity	Rims1	IMP	MGI:MGI:2178099	Mouse	PMID:11797010
Biological Process	GO:0042391	regulation of membrane potential	Rims1	IDA		Mouse	PMID:20452978
Biological Process	GO:0061669	spontaneous neurotransmitter secretion	Rims1	IGI	UniProtKB:Q99NE5\|UniProtKB:Q9EQZ7	Mouse	MGI:MGI:4887275\|PMID:21262469
Biological Process	GO:0016081	synaptic vesicle docking	Rims1	IDA		Mouse	PMID:21241895
Biological Process	GO:0016081	synaptic vesicle docking	Rims1	IMP		Mouse	PMID:21241895
Biological Process	GO:0016082	synaptic vesicle priming	Rims1	IDA		Mouse	PMID:22753485
Biological Process	GO:0016082	synaptic vesicle priming	Rims1	IMP		Mouse	PMID:22753485
Biological Process	GO:0016082	synaptic vesicle priming	Rims1	IDA		Mouse	PMID:21262469
Biological Process	GO:0016082	synaptic vesicle priming	Rims1	IMP		Mouse	PMID:21262469

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.