Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RIPK1
  • Mouse genes Ripk1
  • Rat genes Ripk1
  • Zfish genes ripk1l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ripk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070513	death domain binding	RIPK1	IPI	UniProtKB:Q15628	Human	PMID:8612133
Molecular Function	GO:0070513	death domain binding	RIPK1	IPI	UniProtKB:P78560	Human	PMID:9044836
Molecular Function	GO:0005123	death receptor binding	RIPK1	IPI	UniProtKB:P25445	Human	PMID:7538908
Molecular Function	GO:0005123	death receptor binding	Ripk1	IPI	RGD:619831	Rat	PMID:10386469|RGD:8662865
Molecular Function	GO:0042802	identical protein binding	RIPK1	IPI	UniProtKB:Q13546	Human	PMID:22817896
Molecular Function	GO:0042802	identical protein binding	RIPK1	IPI	UniProtKB:Q13546	Human	PMID:23473668
Molecular Function	GO:0042802	identical protein binding	RIPK1	IPI	UniProtKB:Q13546	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	RIPK1	IPI	UniProtKB:Q13546	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P37198	Human	PMID:10356400
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:12884866
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q92851	Human	PMID:12884866
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:12887920
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9Y6K9	Human	PMID:14653779
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q7Z434	Human	PMID:16127453
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P19438	Human	PMID:16611992
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:17047155
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q5VWQ8	Human	PMID:17389591
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9BYM8	Human	PMID:17449468
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P19438	Human	PMID:18022363
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q8IVM0	Human	PMID:18029035
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P48729	Human	PMID:18067272
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:18485876
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:19060883
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:19524512
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9Y572	Human	PMID:19524512
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P19438	Human	PMID:19524513
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13158	Human	PMID:19524513
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:19524513
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9Y572	Human	PMID:19524513
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P19438	Human	PMID:19781631
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P04083	Human	PMID:21383699
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9Y6K9	Human	PMID:21383699
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13158	Human	PMID:21458669
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:21458669
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9Y6K9	Human	PMID:21458669
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13158	Human	PMID:21525013
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:21525013
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q12933	Human	PMID:21810480
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q92974	Human	PMID:21887730
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13489	Human	PMID:21931591
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13490	Human	PMID:21931591
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:22173242
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9Y572	Human	PMID:22265413
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9Y572	Human	PMID:22265414
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:22274400
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P19438	Human	PMID:22817896
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9Y572	Human	PMID:22817896
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9Y6K9	Human	PMID:23104095
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13107	Human	PMID:23313255
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:23955153
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:B7UI21	Human	PMID:24025841
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P19438	Human	PMID:24130170
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9ULZ3	Human	PMID:25402006
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q8IUC6	Human	PMID:25736436
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:25911380
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P89462	Human	PMID:26559832
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9Y572	Human	PMID:26559832
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:U5TQE9	Human	PMID:26559832
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q96FA3	Human	PMID:29883609
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9Y572	Human	PMID:29883609
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q12933	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13158	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13490	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q9Y6K9	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13114	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13158	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P0DTD1:PRO_0000449629	Human	PMID:32353859
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q13158	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:Q14790	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P0DTD1:PRO_0000449629	Human	PMID:33060197
Molecular Function	GO:0005515	protein binding	RIPK1	IPI	UniProtKB:P0DTD1:PRO_0000449629	Human	PMID:34663909
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:Q61160	Mouse	MGI:MGI:5566546|PMID:24557836
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:P25118	Mouse	MGI:MGI:5508636|PMID:16680093
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:Q9QZL0	Mouse	MGI:MGI:5437800|PMID:22922364
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:Q3UKC1	Mouse	MGI:MGI:3774677|PMID:18246070
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:Q61160	Mouse	MGI:MGI:6093208|PMID:18946037
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:O88522	Mouse	MGI:MGI:6362112|PMID:31519886
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:O43464	Mouse	MGI:MGI:5306563|PMID:20125124
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:P25118|UniProtKB:Q3U0V2	Mouse	MGI:MGI:3806433|PMID:18719121
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:Q8C669	Mouse	MGI:MGI:6163945|PMID:29883609
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:O35732|UniProtKB:O89110|UniProtKB:Q61160|UniProtKB:Q62073|UniProtKB:Q9QZL0	Mouse	MGI:MGI:6362574|PMID:31519887
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:P01375|UniProtKB:Q61160	Mouse	MGI:MGI:5706670|PMID:26649818
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:Q61160	Mouse	MGI:MGI:4947443|PMID:21368763
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:Q61160	Mouse	MGI:MGI:5315337|PMID:21052097
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:Q61160	Mouse	MGI:MGI:6120592|PMID:29440439
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:Q61160|UniProtKB:Q9QZL0	Mouse	MGI:MGI:5926457|PMID:28842570
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:P25118	Mouse	MGI:MGI:5512838|PMID:18022363
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:Q61160|UniProtKB:Q9QZL0	Mouse	MGI:MGI:4359574|PMID:19524513
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:Q61160	Mouse	MGI:MGI:5698536|PMID:26555174
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	PR:Q8K3K8	Mouse	PMID:17702576
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	PR:P25118	Mouse	PMID:17702576
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	PR:Q8BXR6	Mouse	PMID:24113711
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	UniProtKB:Q9Y6K9	Mouse	PMID:17702576
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	PR:Q8C669	Mouse	PMID:19734906
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	RGD:1310457	Rat	PMID:12786973|RGD:2298728
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	RGD:621313	Rat	PMID:12786973|RGD:2298728
Molecular Function	GO:0005515	protein binding	Ripk1	IPI	RGD:628700	Rat	PMID:26038570|RGD:11341801
Molecular Function	GO:0005515	protein binding	ripk1l	IPI	UniProtKB:Q1LUQ2	Zfish	PMID:17372010
Molecular Function	GO:0042803	protein homodimerization activity	RIPK1	IDA		Human	PMID:29440439
Molecular Function	GO:0042803	protein homodimerization activity	Ripk1	IDA		Mouse	MGI:MGI:6120592|PMID:29440439
Molecular Function	GO:0004672	protein kinase activity	RIPK1	IDA		Human	PMID:15001576
Molecular Function	GO:0004672	protein kinase activity	RIPK1	IDA		Human	PMID:22265413
Molecular Function	GO:0004672	protein kinase activity	RIPK1	IMP		Human	PMID:22817896
Molecular Function	GO:0004672	protein kinase activity	Ripk1	IMP		Mouse	MGI:MGI:6120592|PMID:29440439
Molecular Function	GO:0004674	protein serine/threonine kinase activity	RIPK1	IDA		Human	PMID:23473668
Molecular Function	GO:0004674	protein serine/threonine kinase activity	RIPK1	IMP		Human	PMID:30988283
Molecular Function	GO:0004674	protein serine/threonine kinase activity	RIPK1	IMP		Human	PMID:31827280
Molecular Function	GO:0004674	protein serine/threonine kinase activity	RIPK1	IDA		Human	PMID:8612133
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Ripk1	IDA		Mouse	MGI:MGI:5912943|PMID:28701375
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Ripk1	IMP		Mouse	MGI:MGI:6305600|PMID:30988283
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Ripk1	IMP		Mouse	MGI:MGI:6401044|PMID:31827281
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Ripk1	IMP		Mouse	MGI:MGI:6362574|PMID:31519887
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Ripk1	IMP		Mouse	MGI:MGI:5907398|PMID:27819682
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Ripk1	IMP		Mouse	MGI:MGI:6362112|PMID:31519886
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Ripk1	IMP		Mouse	MGI:MGI:6378798|PMID:31511692
Molecular Function	GO:0044877	protein-containing complex binding	RIPK1	IDA		Human	PMID:22265414
Molecular Function	GO:0044877	protein-containing complex binding	Ripk1	IPI	RGD:621237|RGD:621313|RGD:1310457|RGD:620690	Rat	PMID:15590916|RGD:1624191
Molecular Function	GO:0031625	ubiquitin protein ligase binding	RIPK1	IPI	UniProtKB:Q8WZ73	Human	PMID:18450452
Cellular Component	GO:0031264	death-inducing signaling complex	RIPK1	IDA		Human	PMID:11101870
Cellular Component	GO:0045121	membrane raft	Ripk1	IDA		Rat	PMID:15590916|RGD:1624191
Cellular Component	GO:0005739	mitochondrion	RIPK1	IDA		Human	PMID:16507998
Cellular Component	GO:0032991	protein-containing complex	RIPK1	IDA		Human	PMID:22817896
Cellular Component	GO:0032991	protein-containing complex	Ripk1	IDA		Rat	PMID:12786973|RGD:2298728
Cellular Component	GO:0032991	protein-containing complex	Ripk1	IDA		Rat	PMID:15590916|RGD:1624191
Cellular Component	GO:0043235	receptor complex	RIPK1	IDA		Human	PMID:8612133
Cellular Component	GO:0097342	ripoptosome	RIPK1	IDA		Human	PMID:21737330
Biological Process	GO:1990000	amyloid fibril formation	RIPK1	IMP		Human	PMID:22817896
Biological Process	GO:0006915	apoptotic process	RIPK1	IMP		Human	PMID:21737330
Biological Process	GO:0006915	apoptotic process	RIPK1	IMP		Human	PMID:22891283
Biological Process	GO:0006915	apoptotic process	RIPK1	IMP		Human	PMID:29440439
Biological Process	GO:0006915	apoptotic process	Ripk1	IMP		Mouse	MGI:MGI:6362112|PMID:31519886
Biological Process	GO:0006915	apoptotic process	Ripk1	IMP		Mouse	MGI:MGI:6369186|PMID:30867408
Biological Process	GO:0006915	apoptotic process	Ripk1	IMP		Mouse	MGI:MGI:5926457|PMID:28842570
Biological Process	GO:0006915	apoptotic process	Ripk1	IMP		Mouse	MGI:MGI:6362574|PMID:31519887
Biological Process	GO:0006915	apoptotic process	Ripk1	IMP		Mouse	MGI:MGI:6120592|PMID:29440439
Biological Process	GO:0006915	apoptotic process	Ripk1	IMP		Mouse	MGI:MGI:6378798|PMID:31511692
Biological Process	GO:0008219	cell death	RIPK1	IMP		Human	PMID:30988283
Biological Process	GO:0008219	cell death	Ripk1	IMP		Mouse	MGI:MGI:6305600|PMID:30988283
Biological Process	GO:0071363	cellular response to growth factor stimulus	Ripk1	IMP		Mouse	MGI:MGI:5306563|PMID:20125124
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Ripk1	IMP		Mouse	MGI:MGI:6140989|PMID:27258785
Biological Process	GO:0071356	cellular response to tumor necrosis factor	RIPK1	IDA		Human	PMID:17389591
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	RIPK1	IMP		Human	PMID:10521396
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	RIPK1	IDA		Human	PMID:7538908
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	RIPK1	IMP		Human	PMID:8612133
Biological Process	GO:0070266	necroptotic process	RIPK1	IMP		Human	PMID:21737330
Biological Process	GO:0070266	necroptotic process	RIPK1	IMP		Human	PMID:22265414
Biological Process	GO:0070266	necroptotic process	RIPK1	IMP		Human	PMID:29440439
Biological Process	GO:0070266	necroptotic process	Ripk1	IMP		Mouse	MGI:MGI:6369186|PMID:30867408
Biological Process	GO:0070266	necroptotic process	Ripk1	IDA		Mouse	MGI:MGI:5912943|PMID:28701375
Biological Process	GO:0070266	necroptotic process	Ripk1	IMP		Mouse	MGI:MGI:5926457|PMID:28842570
Biological Process	GO:0070266	necroptotic process	Ripk1	IMP		Mouse	MGI:MGI:6362574|PMID:31519887
Biological Process	GO:0070266	necroptotic process	Ripk1	IMP		Mouse	MGI:MGI:6362112|PMID:31519886
Biological Process	GO:0070266	necroptotic process	Ripk1	IMP		Mouse	MGI:MGI:6120592|PMID:29440439
Biological Process	GO:0070266	necroptotic process	Ripk1	IGI	MGI:MGI:1921506	Mouse	PMID:22037414
Biological Process	GO:0070266	necroptotic process	Ripk1	IGI	MGI:MGI:2154952	Mouse	PMID:22037414
Biological Process	GO:0070266	necroptotic process	Ripk1	IGI	MGI:MGI:104798	Mouse	PMID:21052097
Biological Process	GO:0070266	necroptotic process	Ripk1	IGI	MGI:MGI:2154952	Mouse	PMID:19498109
Biological Process	GO:0070266	necroptotic process	Ripk1	IGI	MGI:MGI:95484	Mouse	PMID:21052097
Biological Process	GO:0070266	necroptotic process	Ripk1	IGI	MGI:MGI:104798	Mouse	PMID:19498109
Biological Process	GO:0097527	necroptotic signaling pathway	RIPK1	IMP		Human	PMID:11101870
Biological Process	GO:0097527	necroptotic signaling pathway	RIPK1	IMP		Human	PMID:16507998
Biological Process	GO:0097527	necroptotic signaling pathway	RIPK1	IMP		Human	PMID:22265413
Biological Process	GO:0097527	necroptotic signaling pathway	RIPK1	IMP		Human	PMID:22817896
Biological Process	GO:0097527	necroptotic signaling pathway	RIPK1	IMP		Human	PMID:31827280
Biological Process	GO:0097527	necroptotic signaling pathway	Ripk1	IMP		Mouse	MGI:MGI:5291865|PMID:21876153
Biological Process	GO:0097527	necroptotic signaling pathway	Ripk1	IMP		Mouse	MGI:MGI:6401044|PMID:31827281
Biological Process	GO:0043066	negative regulation of apoptotic process	Ripk1	IMP		Mouse	MGI:MGI:5907398|PMID:27819682
Biological Process	GO:0043066	negative regulation of apoptotic process	Ripk1	IMP		Mouse	MGI:MGI:6377951|PMID:30185824
Biological Process	GO:0043066	negative regulation of apoptotic process	Ripk1	IMP		Mouse	MGI:MGI:5602911|PMID:24813849
Biological Process	GO:0043066	negative regulation of apoptotic process	Ripk1	IMP		Mouse	MGI:MGI:5602910|PMID:24813850
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	RIPK1	IMP		Human	PMID:21525013
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	Ripk1	IGI	MGI:MGI:109200	Mouse	PMID:22089168
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	Ripk1	IGI	MGI:MGI:104798	Mouse	PMID:22089168
Biological Process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Ripk1	IMP		Mouse	MGI:MGI:5306563|PMID:20125124
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	RIPK1	IMP		Human	PMID:17047155
Biological Process	GO:0060546	negative regulation of necroptotic process	Ripk1	IMP		Mouse	MGI:MGI:5907398|PMID:27819682
Biological Process	GO:0060546	negative regulation of necroptotic process	Ripk1	IMP		Mouse	MGI:MGI:5602910|PMID:24813850
Biological Process	GO:0060546	negative regulation of necroptotic process	Ripk1	IMP		Mouse	MGI:MGI:5907399|PMID:27819681
Biological Process	GO:0060546	negative regulation of necroptotic process	Ripk1	IMP		Mouse	MGI:MGI:5602911|PMID:24813849
Biological Process	GO:0036289	peptidyl-serine autophosphorylation	RIPK1	IDA		Human	PMID:23473668
Biological Process	GO:0036289	peptidyl-serine autophosphorylation	RIPK1	IMP		Human	PMID:31827280
Biological Process	GO:0036289	peptidyl-serine autophosphorylation	Ripk1	IMP		Mouse	MGI:MGI:6401044|PMID:31827281
Biological Process	GO:0043065	positive regulation of apoptotic process	RIPK1	IDA		Human	PMID:17389591
Biological Process	GO:0043065	positive regulation of apoptotic process	RIPK1	IMP		Human	PMID:22173242
Biological Process	GO:0043065	positive regulation of apoptotic process	RIPK1	IDA		Human	PMID:8612133
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	RIPK1	IMP		Human	PMID:21525013
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	RIPK1	IMP		Human	PMID:22274400
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	Ripk1	IGI	MGI:MGI:104798	Mouse	PMID:19498109
Biological Process	GO:0010628	positive regulation of gene expression	RIPK1	IDA		Human	PMID:26020802
Biological Process	GO:1905206	positive regulation of hydrogen peroxide-induced cell death	RIPK1	IMP		Human	PMID:20550618
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	RIPK1	IEP		Human	PMID:12761501
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	RIPK1	IDA		Human	PMID:17389591
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Ripk1	IMP		Mouse	PMID:22089168
Biological Process	GO:0050729	positive regulation of inflammatory response	RIPK1	IMP		Human	PMID:31827280
Biological Process	GO:0050729	positive regulation of inflammatory response	Ripk1	IMP		Mouse	MGI:MGI:6401044|PMID:31827281
Biological Process	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway	RIPK1	IMP		Human	PMID:31827280
Biological Process	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway	Ripk1	IMP		Mouse	MGI:MGI:6401044|PMID:31827281
Biological Process	GO:0032757	positive regulation of interleukin-8 production	RIPK1	IDA		Human	PMID:16127453
Biological Process	GO:0046330	positive regulation of JNK cascade	RIPK1	IDA		Human	PMID:17389591
Biological Process	GO:0046330	positive regulation of JNK cascade	Ripk1	IMP		Mouse	MGI:MGI:5306563|PMID:20125124
Biological Process	GO:0045651	positive regulation of macrophage differentiation	RIPK1	IMP		Human	PMID:17047155
Biological Process	GO:0043410	positive regulation of MAPK cascade	Ripk1	IMP		Mouse	MGI:MGI:5306563|PMID:20125124
Biological Process	GO:0060545	positive regulation of necroptotic process	RIPK1	IMP		Human	PMID:22028622
Biological Process	GO:0060545	positive regulation of necroptotic process	RIPK1	IMP		Human	PMID:22274400
Biological Process	GO:0060545	positive regulation of necroptotic process	RIPK1	IMP		Human	PMID:22817896
Biological Process	GO:0060545	positive regulation of necroptotic process	Ripk1	IMP		Rat	PMID:22372834|RGD:7777172
Biological Process	GO:0060545	positive regulation of necroptotic process	Ripk1	IMP		Rat	PMID:23386613|RGD:7777171
Biological Process	GO:0010940	positive regulation of necrotic cell death	RIPK1	IMP		Human	PMID:20550618
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Ripk1	IMP		Rat	PMID:32308116|RGD:156420143
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	RIPK1	IMP		Human	PMID:10521396
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	RIPK1	IMP		Human	PMID:21931591
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	RIPK1	IMP		Human	PMID:8612133
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Ripk1	IMP		Mouse	MGI:MGI:5306563|PMID:20125124
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Ripk1	IMP		Mouse	MGI:MGI:6362574|PMID:31519887
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Ripk1	IMP		Mouse	MGI:MGI:6362112|PMID:31519886
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	Ripk1	IMP		Rat	PMID:32308116|RGD:156420143
Biological Process	GO:0042327	positive regulation of phosphorylation	Ripk1	IMP		Mouse	MGI:MGI:5315337|PMID:21052097
Biological Process	GO:0043068	positive regulation of programmed cell death	RIPK1	IMP		Human	PMID:16611992
Biological Process	GO:0001934	positive regulation of protein phosphorylation	RIPK1	IMP		Human	PMID:17389591
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	RIPK1	IDA		Human	PMID:16127453
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	RIPK1	IDA		Human	PMID:17389591
Biological Process	GO:0051347	positive regulation of transferase activity	Ripk1	IGI	MGI:MGI:2154952	Mouse	PMID:19498109
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	RIPK1	IDA		Human	PMID:16127453
Biological Process	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	Ripk1	IDA		Mouse	MGI:MGI:6271183|PMID:30439713
Biological Process	GO:0097300	programmed necrotic cell death	Ripk1	IMP		Mouse	MGI:MGI:6140989|PMID:27258785
Biological Process	GO:0046777	protein autophosphorylation	RIPK1	IMP		Human	PMID:29440439
Biological Process	GO:0046777	protein autophosphorylation	RIPK1	IDA		Human	PMID:8612133
Biological Process	GO:0046777	protein autophosphorylation	Ripk1	IMP		Mouse	MGI:MGI:6305600|PMID:30988283
Biological Process	GO:0046777	protein autophosphorylation	Ripk1	IMP		Mouse	MGI:MGI:6120592|PMID:29440439
Biological Process	GO:0030163	protein catabolic process	RIPK1	IDA		Human	PMID:17389591
Biological Process	GO:0070926	regulation of ATP:ADP antiporter activity	RIPK1	IMP		Human	PMID:16507998
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	Ripk1	IMP		Mouse	PMID:21052097
Biological Process	GO:0034612	response to tumor necrosis factor	RIPK1	IMP		Human	PMID:10521396
Biological Process	GO:0097343	ripoptosome assembly	RIPK1	IMP		Human	PMID:21737330
Biological Process	GO:1901026	ripoptosome assembly involved in necroptotic process	Ripk1	IGI	MGI:MGI:1197009	Mouse	PMID:21052097
Biological Process	GO:1901026	ripoptosome assembly involved in necroptotic process	Ripk1	IGI	MGI:MGI:1346877	Mouse	PMID:21052097
Biological Process	GO:1901026	ripoptosome assembly involved in necroptotic process	Ripk1	IGI	MGI:MGI:104798	Mouse	PMID:21052097
Biological Process	GO:0070231	T cell apoptotic process	Ripk1	IMP		Mouse	MGI:MGI:5291865|PMID:21876153

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern