Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RLIM
  • Mouse genes Rlim
  • Rat genes Rlim
  • Zfish genes rlim
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rlim

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Rlim	IPI	UniProtKB:O55203	Mouse	MGI:MGI:6092914|PMID:17848518
Molecular Function	GO:0005515	protein binding	Rlim	IPI	UniProtKB:P53668	Mouse	MGI:MGI:3603857|PMID:16204183
Molecular Function	GO:0005515	protein binding	Rlim	IPI	UniProtKB:O55203|UniProtKB:P50481|UniProtKB:P70662|UniProtKB:Q60520	Mouse	MGI:MGI:4456957|PMID:11882901
Molecular Function	GO:0005515	protein binding	Rlim	IPI	UniProtKB:P22227	Mouse	MGI:MGI:5320504|PMID:22596162
Molecular Function	GO:0005515	protein binding	Rlim	IPI	PR:P25801	Mouse	PMID:10431247
Molecular Function	GO:0005515	protein binding	Rlim	IPI	PR:P50481	Mouse	PMID:10431247
Molecular Function	GO:0005515	protein binding	Rlim	IPI	PR:Q60520	Mouse	PMID:10431247
Molecular Function	GO:0005515	protein binding	Rlim	IPI	PR:P53668	Mouse	PMID:10431247
Molecular Function	GO:0005515	protein binding	Rlim	IPI	PR:P61372	Mouse	PMID:10431247
Molecular Function	GO:0005515	protein binding	Rlim	IPI	PR:O55203	Mouse	PMID:10431247
Molecular Function	GO:0005515	protein binding	Rlim	IPI	PR:Q9Z0S2	Mouse	PMID:10431247
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Rlim	IDA		Mouse	PMID:16204183
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Rlim	IDA		Mouse	MGI:MGI:4456957|PMID:11882901
Cellular Component	GO:0005829	cytosol	RLIM	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	RLIM	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Rlim	IDA		Mouse	MGI:MGI:4418586|PMID:19945382
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	Rlim	IGI	MGI:MGI:894670	Mouse	PMID:10431247
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Rlim	IGI	MGI:MGI:97588	Mouse	PMID:10431247
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Rlim	IGI	MGI:MGI:894670	Mouse	PMID:10431247
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Rlim	IGI	MGI:MGI:96785	Mouse	PMID:10431247
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Rlim	IGI	MGI:MGI:107157	Mouse	PMID:10431247
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Rlim	IGI	MGI:MGI:107374	Mouse	PMID:10431247
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Rlim	IGI	MGI:MGI:102673	Mouse	PMID:10431247
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Rlim	IGI	MGI:MGI:1097691	Mouse	PMID:10431247
Biological Process	GO:0016567	protein ubiquitination	Rlim	IDA		Mouse	MGI:MGI:4456957|PMID:11882901
Biological Process	GO:0060816	random inactivation of X chromosome	RLIM	IDA		Human	PMID:19945382
Biological Process	GO:0060816	random inactivation of X chromosome	Rlim	IDA		Mouse	MGI:MGI:4418586|PMID:19945382
Biological Process	GO:1900095	regulation of dosage compensation by inactivation of X chromosome	Rlim	IMP		Mouse	PMID:24613346
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	rlim	IMP	ZFIN:ZDB-MRPHLNO-120824-4,ZFIN:ZDB-MRPHLNO-120824-5	Zfish	PMID:22560923
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Rlim	IDA		Mouse	MGI:MGI:4456957|PMID:11882901

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern