Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RLN1,RLN2
  • Mouse genes Rln1
  • Rat genes Rln1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rln1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RLN1	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RLN1	IPI	UniProtKB:Q9UJV3-2	Human	PMID:32296183
Molecular Function	GO:0005102	signaling receptor binding	Rln1	IDA		Mouse	PMID:8216305
Biological Process	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	Rln1	IGI	UniProtKB:Q6R6I6	Rat	PMID:19073841|RGD:8553970
Biological Process	GO:0048589	developmental growth	Rln1	IMP	MGI:MGI:2668458	Mouse	PMID:12861045
Biological Process	GO:0060443	mammary gland morphogenesis	Rln1	IMP		Mouse	MGI:MGI:1327714|PMID:9886856
Biological Process	GO:0043066	negative regulation of apoptotic process	Rln1	IMP		Rat	PMID:15498891|RGD:10047365
Biological Process	GO:0060618	nipple development	Rln1	IMP		Mouse	MGI:MGI:1327714|PMID:9886856
Biological Process	GO:0045766	positive regulation of angiogenesis	RLN2	IMP		Human	PMID:16049981
Biological Process	GO:0010628	positive regulation of gene expression	RLN2	IDA		Human	PMID:11459784
Biological Process	GO:0060736	prostate gland growth	Rln1	IMP	MGI:MGI:2668458	Mouse	PMID:12861045
Biological Process	GO:0042981	regulation of apoptotic process	Rln1	IMP		Mouse	MGI:MGI:2668302|PMID:12861045
Biological Process	GO:0050790	regulation of catalytic activity	RLN2	IDA		Human	PMID:16049981
Biological Process	GO:0042127	regulation of cell population proliferation	Rln1	IMP		Rat	PMID:15498891|RGD:10047365
Biological Process	GO:0010749	regulation of nitric oxide mediated signal transduction	Rln1	IMP	MGI:MGI:2668458	Mouse	PMID:19073841
Biological Process	GO:0010749	regulation of nitric oxide mediated signal transduction	Rln1	IDA		Rat	PMID:19073841|RGD:8553970
Biological Process	GO:0007283	spermatogenesis	Rln1	IMP		Mouse	MGI:MGI:2668302|PMID:12861045

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern