Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF115
  • Mouse genes Rnf115
  • Rat genes Rnf115
  • Zfish genes rnf115a,rnf115b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf115

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:P51149	Human	PMID:16925951
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:P51668	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:P61077	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:P62837	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:Q969T4	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:Q9Y2X8	Human	PMID:19690564
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:Q15038	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:O15151	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:P51668	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:P61077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:Q15038	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:Q9Y2X8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:P51668	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:Q15038	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:Q9Y2X8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:P51668	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:P61077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:P62837	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:Q969T4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:Q96LR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:Q9Y2X8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:P55072	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RNF115	IPI	UniProtKB:Q00987	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Rnf115	IPI	UniProtKB:P51150	Mouse	MGI:MGI:4821079|PMID:12972561
Molecular Function	GO:0005515	protein binding	Rnf115	IPI	UniProtKB:P00533	Mouse	MGI:MGI:5582879|PMID:23418353
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Rnf115	IDA		Mouse	MGI:MGI:5582879|PMID:23418353
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF115	IDA		Human	PMID:18819927
Cellular Component	GO:0005829	cytosol	Rnf115	IDA		Mouse	MGI:MGI:4821079|PMID:12972561
Biological Process	GO:0007368	determination of left/right symmetry	rnf115a	IMP	ZFIN:ZDB-MRPHLNO-180926-4	Zfish	PMID:29843777
Biological Process	GO:0007368	determination of left/right symmetry	rnf115a	IMP	ZFIN:ZDB-CRISPR-180927-1	Zfish	PMID:29843777
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	RNF115	IMP		Human	PMID:23418353
Biological Process	GO:0051865	protein autoubiquitination	RNF115	IDA		Human	PMID:16288031
Biological Process	GO:0070936	protein K48-linked ubiquitination	Rnf115	IDA		Mouse	MGI:MGI:5582879|PMID:23418353
Biological Process	GO:0070534	protein K63-linked ubiquitination	Rnf115	IDA		Mouse	MGI:MGI:5582879|PMID:23418353
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	RNF115	IMP		Human	PMID:23418353

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern