Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF125
  • Mouse genes Rnf125
  • Rat genes Rnf125
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf125

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002039	p53 binding	RNF125	IPI	UniProtKB:P04637	Human	PMID:25591766
Molecular Function	GO:0005515	protein binding	RNF125	IPI	UniProtKB:O95786	Human	PMID:17460044
Molecular Function	GO:0005515	protein binding	RNF125	IPI	UniProtKB:O95786-1	Human	PMID:17460044
Molecular Function	GO:0005515	protein binding	RNF125	IPI	UniProtKB:Q7Z434	Human	PMID:17460044
Molecular Function	GO:0005515	protein binding	RNF125	IPI	UniProtKB:Q7Z434-1	Human	PMID:17460044
Molecular Function	GO:0005515	protein binding	RNF125	IPI	UniProtKB:Q96LR5	Human	PMID:17460044
Molecular Function	GO:0005515	protein binding	RNF125	IPI	UniProtKB:Q9BYX4	Human	PMID:17460044
Molecular Function	GO:0005515	protein binding	RNF125	IPI	UniProtKB:Q96LR5	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF125	IPI	UniProtKB:O95786	Human	PMID:26471729
Molecular Function	GO:0031624	ubiquitin conjugating enzyme binding	RNF125	IPI	UniProtKB:P51668	Human	PMID:27411375
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF125	IDA		Human	PMID:17460044
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF125	IDA		Human	PMID:25591766
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF125	IDA		Human	PMID:27411375
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Rnf125	EXP		Mouse	MGI:MGI:5770075|PMID:17460044
Molecular Function	GO:0008270	zinc ion binding	RNF125	IDA		Human	PMID:27411375
Cellular Component	GO:0000139	Golgi membrane	RNF125	IDA		Human	PMID:17990982
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	RNF125	IDA		Human	PMID:17990982
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	RNF125	IDA		Human	PMID:26471729
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Rnf125	IEP		Mouse	PMID:20439489
Biological Process	GO:0039536	negative regulation of RIG-I signaling pathway	RNF125	IDA		Human	PMID:17460044
Biological Process	GO:0039536	negative regulation of RIG-I signaling pathway	RNF125	IDA		Human	PMID:26471729
Biological Process	GO:0032480	negative regulation of type I interferon production	RNF125	IDA		Human	PMID:17460044
Biological Process	GO:0032480	negative regulation of type I interferon production	RNF125	IDA		Human	PMID:26471729
Biological Process	GO:0000209	protein polyubiquitination	RNF125	IDA		Human	PMID:27411375
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	RNF125	IDA		Human	PMID:17460044
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	RNF125	IDA		Human	PMID:26471729

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern