Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF126
  • Mouse genes Rnf126
  • Rat genes Rnf126
  • Zfish genes rnf126
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf126

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005154	epidermal growth factor receptor binding	Rnf126	IPI	UniProtKB:P00533	Mouse	MGI:MGI:5582879|PMID:23418353
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P46379	Human	PMID:14667819
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P51668	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P61077	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:Q9Y2X8	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P51668	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P61077	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:Q9Y2X8	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P38936	Human	PMID:23026136
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:Q9GZX7	Human	PMID:23277564
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P46379	Human	PMID:24981174
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P46379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P51668	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P46379	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P46379-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P46379	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P51668	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P61077	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RNF126	IPI	UniProtKB:P46379-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Rnf126	IPI	UniProtKB:O14828|UniProtKB:Q00342|UniProtKB:Q8IVM0	Mouse	MGI:MGI:5582879|PMID:23418353
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF126	IDA		Human	PMID:23026136
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF126	IDA		Human	PMID:24981174
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Rnf126	IDA		Mouse	MGI:MGI:5582879|PMID:23418353
Cellular Component	GO:0005737	cytoplasm	RNF126	IDA		Human	PMID:23026136
Cellular Component	GO:0005829	cytosol	RNF126	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	RNF126	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RNF126	IDA		Human	PMID:23026136
Biological Process	GO:0071629	cytoplasm protein quality control by the ubiquitin-proteasome system	RNF126	IMP		Human	PMID:24981174
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	RNF126	IMP		Human	PMID:23418353
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	RNF126	IDA		Human	PMID:24981174
Biological Process	GO:0070936	protein K48-linked ubiquitination	Rnf126	IDA		Mouse	MGI:MGI:5582879|PMID:23418353
Biological Process	GO:0070534	protein K63-linked ubiquitination	Rnf126	IDA		Mouse	MGI:MGI:5582879|PMID:23418353
Biological Process	GO:0006513	protein monoubiquitination	RNF126	IDA		Human	PMID:23277564
Biological Process	GO:0042127	regulation of cell population proliferation	RNF126	IMP		Human	PMID:23026136
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	RNF126	IMP		Human	PMID:24275455
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	RNF126	IMP		Human	PMID:23026136
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	RNF126	IDA		Human	PMID:24981174
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	RNF126	IMP		Human	PMID:23418353

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern