Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF146
  • Mouse genes Rnf146
  • Rat genes Rnf146
  • Zfish genes rnf146
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf146

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	Rnf146	IPI	RGD:2053	Rat	PMID:24842055|RGD:13524867
Molecular Function	GO:0072572	poly-ADP-D-ribose binding	RNF146	IDA		Human	PMID:21478859
Molecular Function	GO:0005515	protein binding	RNF146	IPI	UniProtKB:O15169	Human	PMID:21478859
Molecular Function	GO:0005515	protein binding	RNF146	IPI	UniProtKB:O15234	Human	PMID:21478859
Molecular Function	GO:0005515	protein binding	RNF146	IPI	UniProtKB:Q9H2G9	Human	PMID:21478859
Molecular Function	GO:0005515	protein binding	RNF146	IPI	UniProtKB:Q9Y2T1	Human	PMID:21478859
Molecular Function	GO:0005515	protein binding	RNF146	IPI	UniProtKB:O95271	Human	PMID:21799911
Molecular Function	GO:0005515	protein binding	RNF146	IPI	UniProtKB:P09874	Human	PMID:21799911
Molecular Function	GO:0005515	protein binding	RNF146	IPI	UniProtKB:O95271	Human	PMID:25327252
Molecular Function	GO:0005515	protein binding	RNF146	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF146	IPI	UniProtKB:Q8N6L0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF146	IPI	UniProtKB:Q9UGJ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Rnf146	IPI	UniProtKB:P51668	Mouse	MGI:MGI:5914430|PMID:25327252
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF146	IDA		Human	PMID:21478859
Cellular Component	GO:0005737	cytoplasm	Rnf146	IDA		Rat	PMID:24842055|RGD:13524867
Cellular Component	GO:0005829	cytosol	RNF146	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	RNF146	IDA		Human	PMID:15813938
Cellular Component	GO:0005654	nucleoplasm	RNF146	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Rnf146	IDA		Rat	PMID:24842055|RGD:13524867
Cellular Component	GO:0005886	plasma membrane	RNF146	IDA		Human	GO_REF:0000052
Biological Process	GO:0071333	cellular response to glucose stimulus	Rnf146	IEP		Rat	PMID:26218637|RGD:13524866
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Rnf146	IMP		Rat	PMID:24842055|RGD:13524867
Biological Process	GO:0071456	cellular response to hypoxia	Rnf146	IEP		Rat	PMID:26218637|RGD:13524866
Biological Process	GO:1900408	negative regulation of cellular response to oxidative stress	Rnf146	IMP		Rat	PMID:24842055|RGD:13524867
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	RNF146	IMP		Human	PMID:21478859
Biological Process	GO:0051865	protein autoubiquitination	RNF146	IDA		Human	PMID:21478859
Biological Process	GO:0070936	protein K48-linked ubiquitination	RNF146	IMP		Human	PMID:21478859
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	RNF146	IMP		Human	PMID:21478859

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern