About   Help   FAQ
Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Rnf2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf2
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003682chromatin bindingRNF2IDAHumanPMID:25519132
Molecular FunctionGO:0003682chromatin bindingRnf2IDAMousePMID:15741318
Molecular FunctionGO:0003682chromatin bindingRnf2IDAMousePMID:16687444
Molecular FunctionGO:0003682chromatin bindingRnf2IDAMousePMID:12183370
Molecular FunctionGO:0140862histone H2AK119 ubiquitin ligase activityRnf2IMPMouseMGI:MGI:5527017|PMID:24034696
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O95931HumanPMID:10369680
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:15386022
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q06587HumanPMID:15386022
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9H7Z6HumanPMID:15960975
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O00257HumanPMID:16169070
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:16710298
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q06587HumanPMID:16943429
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q6W2J9HumanPMID:16943429
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q8N488HumanPMID:16943429
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BSM1HumanPMID:16943429
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P08183HumanPMID:17088979
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9HC52HumanPMID:17332741
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q12800-1HumanPMID:18629613
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q99623HumanPMID:18629613
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O95503HumanPMID:18927235
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O95931HumanPMID:18927235
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9HC52HumanPMID:18927235
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P51668HumanPMID:19549727
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P61077HumanPMID:19549727
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P62837HumanPMID:19549727
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q969T4HumanPMID:19549727
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q96LR5HumanPMID:19549727
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9Y2X8HumanPMID:19549727
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:19636380
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35227HumanPMID:19636380
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9HC52HumanPMID:19636380
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:20543829
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:20601937
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35227HumanPMID:20601937
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P51784HumanPMID:20601937
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q93009HumanPMID:20601937
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O95931HumanPMID:20696397
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q8N488HumanPMID:20696397
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P0C0S8HumanPMID:21179169
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O00257-3HumanPMID:21282530
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O95503HumanPMID:21282530
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O95931HumanPMID:21282530
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P67870HumanPMID:21282530
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P68400HumanPMID:21282530
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9HC52HumanPMID:21282530
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:21772249
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:22493164
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35227HumanPMID:22493164
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q3KNV8HumanPMID:22493164
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q86SE9HumanPMID:22493164
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BSM1HumanPMID:22493164
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BYE7HumanPMID:22493164
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:22902369
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O95931HumanPMID:23523425
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O95503HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O95931HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35227HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q06587HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q3KNV8HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q86SE9HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q8N488HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BSM1HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BYE7HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9HC52HumanPMID:24981860
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q86SE9HumanPMID:25519132
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O00257HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q06587HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q8N488HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q93009HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BSM1HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BYE7HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9HC52HumanPMID:26496610
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BSM1HumanPMID:26687479
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BSM1HumanPMID:27505670
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O00257HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O95503HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O95931HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35227HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P67870HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P68400HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q3KNV8HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q86SE9HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q8N488HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BSM1HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BYE7HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9HC52HumanPMID:27705803
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O95931HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35227HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q86SE9HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q8N488HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BYE7HumanPMID:28514442
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:O60356HumanPMID:28720707
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35227HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P51668HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P61077HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P62837HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q3KNV8-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q8IY57-5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q8N488HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q969T4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q96LR5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9BSM1HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q9Y2X8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P68400HumanPMID:32707033
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P49810HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P54253HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P61086HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:P35226HumanPMID:34316702
Molecular FunctionGO:0005515protein bindingRNF2IPIUniProtKB:Q8N488HumanPMID:34316702
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:O35730|UniProtKB:P25916|UniProtKB:Q9QWH1|UniProtKB:Q9QXV1MouseMGI:MGI:3612587|PMID:16359901
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:O35730|UniProtKB:P25916|UniProtKB:Q61177|UniProtKB:Q64028|UniProtKB:Q6P1G2|UniProtKB:Q6ZQ88|UniProtKB:Q9QWH1|UniProtKB:Q9QXV1|UniProtKB:Q9WTX5MouseMGI:MGI:3715707|PMID:17296600
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:Q64028|UniProtKB:Q8CCI5MouseMGI:MGI:5431036|PMID:22325148
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:P23798MouseMGI:MGI:5431036|PMID:22325148
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:P23798|UniProtKB:Q3UK78|UniProtKB:Q8BTQ0|UniProtKB:Q8R023|UniProtKB:Q99NA9MouseMGI:MGI:5908473|PMID:28596365
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:Q9QWH1MouseMGI:MGI:3586402|PMID:16024804
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:Q99LW6MouseMGI:MGI:2679146|PMID:14557078
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:Q8CCI5MouseMGI:MGI:5009373|PMID:19170609
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:P25916|UniProtKB:Q64028MouseMGI:MGI:3807116|PMID:18650381
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:P25916|UniProtKB:Q9QWH1MouseMGI:MGI:1859418|PMID:9627119
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:P23798MouseMGI:MGI:3612587|PMID:16359901
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:Q8CCI5MouseMGI:MGI:1927299|PMID:10369680
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:P23798MouseMGI:MGI:3715707|PMID:17296600
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:P23798MouseMGI:MGI:2389282|PMID:12183370
Molecular FunctionGO:0005515protein bindingRnf2IPIUniProtKB:P25916|UniProtKB:Q64028MouseMGI:MGI:2389282|PMID:12183370
Molecular FunctionGO:0005515protein bindingRnf2IPIPR:Q8BLB7MousePMID:15889154
Molecular FunctionGO:0005515protein bindingRnf2IPIPR:P25916MousePMID:20808772
Molecular FunctionGO:0005515protein bindingRnf2IPIMGI:MGI:1919847MousePMID:25519132
Molecular FunctionGO:0005515protein bindingRnf2IPIPR:P25916MousePMID:17107999
Molecular FunctionGO:0005515protein bindingRnf2IPIPR:P22227MousePMID:21530438
Molecular FunctionGO:0005515protein bindingRnf2IPIPR:P59178MousePMID:22770845
Molecular FunctionGO:0005515protein bindingRnf2IPIPR:Q3TTC2MousePMID:21530438
Molecular FunctionGO:0071535RING-like zinc finger domain bindingRNF2IPIUniProtKB:P35226HumanPMID:16714294
Molecular FunctionGO:0061630ubiquitin protein ligase activityRnf2IDAMouseMGI:MGI:6810795|PMID:24980959
Molecular FunctionGO:0061630ubiquitin protein ligase activityRnf2IDAMousePMID:16359901
Molecular FunctionGO:0004842ubiquitin-protein transferase activityRNF2IDAHumanPMID:16714294
Molecular FunctionGO:0008270zinc ion bindingRNF2IDAHumanPMID:16714294
Cellular ComponentGO:0005737cytoplasmRnf2IDAMouseMGI:MGI:6810795|PMID:24980959
Cellular ComponentGO:0000791euchromatinRnf2IDAMousePMID:18311137
Cellular ComponentGO:0000792heterochromatinRnf2IDAMousePMID:18311137
Cellular ComponentGO:0071339MLL1 complexRNF2IDAHumanPMID:15960975
Cellular ComponentGO:0016604nuclear bodyRNF2IDAHumanGO_REF:0000052
Cellular ComponentGO:0016604nuclear bodyRnf2IDAMousePMID:12183370
Cellular ComponentGO:0005654nucleoplasmRNF2IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusRNF2IDAHumanPMID:18629613
Cellular ComponentGO:0005634nucleusRNF2IDAHumanPMID:21282530
Cellular ComponentGO:0005634nucleusRnf2IDAMouseMGI:MGI:6810795|PMID:24980959
Cellular ComponentGO:0005634nucleusRnf2IDAMousePMID:14557078
Cellular ComponentGO:0005634nucleusRnf2IDAMousePMID:22770845
Cellular ComponentGO:0031519PcG protein complexRNF2IDAHumanPMID:16943429
Cellular ComponentGO:0031519PcG protein complexRNF2IDAHumanPMID:21282530
Cellular ComponentGO:0031519PcG protein complexRnf2IDAMouseMGI:MGI:5908473|PMID:28596365
Cellular ComponentGO:0031519PcG protein complexRnf2IDAMousePMID:16624538
Cellular ComponentGO:0035102PRC1 complexRNF2IDAHumanPMID:12167701
Cellular ComponentGO:0035102PRC1 complexRNF2IDAHumanPMID:19636380
Cellular ComponentGO:0035102PRC1 complexRnf2IDAMousePMID:16359901
Cellular ComponentGO:0001739sex chromatinRnf2IDAMousePMID:15525528
Cellular ComponentGO:0000151ubiquitin ligase complexRNF2IDAHumanPMID:16714294
Biological ProcessGO:0009948anterior/posterior axis specificationRnf2IMPMGI:MGI:2447529MousePMID:12183370
Biological ProcessGO:0006325chromatin organizationRnf2IDAMousePMID:16359901
Biological ProcessGO:0006325chromatin organizationRnf2IGIMGI:MGI:1101770MousePMID:15525528
Biological ProcessGO:0006338chromatin remodelingRNF2IDAHumanPMID:16943429
Biological ProcessGO:0048701embryonic cranial skeleton morphogenesisrnf2IMPZFIN:ZDB-GENO-120611-3ZfishPMID:24040141
Biological ProcessGO:0048701embryonic cranial skeleton morphogenesisrnf2IMPZFIN:ZDB-GENO-120611-2ZfishPMID:24040141
Biological ProcessGO:0040029epigenetic regulation of gene expressionRNF2IMPHumanPMID:33864376
Biological ProcessGO:0001702gastrulation with mouth forming secondRnf2IMPMGI:MGI:2653961MousePMID:12589020
Biological ProcessGO:0010467gene expressionRnf2IMPMousePMID:23027973
Biological ProcessGO:0007281germ cell developmentRnf2IMPMouseMGI:MGI:5475031|PMID:23486062
Biological ProcessGO:0000278mitotic cell cycleRnf2IMPMGI:MGI:2653961MousePMID:12589020
Biological ProcessGO:0043433negative regulation of DNA-binding transcription factor activityRNF2IMPHumanPMID:18629613
Biological ProcessGO:1902254negative regulation of intrinsic apoptotic signaling pathway by p53 class mediatorrnf2IMPZFIN:ZDB-MRPHLNO-120606-5ZfishPMID:23669349
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIRnf2IMPMouseMGI:MGI:5527017|PMID:24034696
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIRnf2IMPMousePMID:16687444
Biological ProcessGO:0033339pectoral fin developmentrnf2IMPZFIN:ZDB-GENO-120611-2ZfishPMID:22619390
Biological ProcessGO:0033339pectoral fin developmentrnf2IMPZFIN:ZDB-GENO-120611-3ZfishPMID:22619390
Biological ProcessGO:0032330regulation of chondrocyte differentiationrnf2IMPZFIN:ZDB-GENO-120611-3ZfishPMID:24040141
Biological ProcessGO:0032330regulation of chondrocyte differentiationrnf2IMPZFIN:ZDB-GENO-120611-2ZfishPMID:24040141
Biological ProcessGO:0032526response to retinoic acidRnf2IEPRatPMID:20515739|RGD:9491842
Biological ProcessGO:0060042retina morphogenesis in camera-type eyernf2IGIZFIN:ZDB-MRPHLNO-120606-5,ZFIN:ZDB-MRPHLNO-130911-9ZfishPMID:23669349
Biological ProcessGO:0021510spinal cord developmentRnf2IEPRatPMID:20515739|RGD:9491842

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/05/2024
MGI 6.24
The Jackson Laboratory