Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF216
  • Mouse genes Rnf216
  • Rat genes Rnf216
  • Zfish genes rnf216
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf216

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:Q13114	Human	PMID:19893624
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:O14933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:O15037	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:O75808	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:P21580	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:P45974-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:P57075-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:P68036	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:Q14149	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:Q5VVQ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:Q8N3F0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:Q8N6M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:Q8TF42	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:Q92567-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:Q96CV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF216	IPI	UniProtKB:Q9BSL1	Human	PMID:32296183
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF216	EXP		Human	PMID:19893624
Cellular Component	GO:0005829	cytosol	RNF216	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098978	glutamatergic synapse	Rnf216	IDA		Rat	PMID:24945773|RGD:11553202
Cellular Component	GO:0098978	glutamatergic synapse	Rnf216	IMP		Rat	PMID:24945773|RGD:11553202
Cellular Component	GO:0005654	nucleoplasm	RNF216	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RNF216	IDA		Human	GO_REF:0000054
Cellular Component	GO:0098843	postsynaptic endocytic zone	Rnf216	IDA		Rat	PMID:24945773|RGD:11553202
Cellular Component	GO:0098793	presynapse	Rnf216	IDA		Rat	PMID:24945773|RGD:11553202
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Rnf216	IDA		Rat	PMID:24945773|RGD:11553202
Biological Process	GO:0043010	camera-type eye development	rnf216	IMP	ZFIN:ZDB-MRPHLNO-140306-1	Zfish	PMID:23656588
Biological Process	GO:0043010	camera-type eye development	rnf216	IGI	ZFIN:ZDB-MRPHLNO-140306-1,ZFIN:ZDB-MRPHLNO-140306-2	Zfish	PMID:23656588
Biological Process	GO:0021549	cerebellum development	rnf216	IGI	ZFIN:ZDB-MRPHLNO-140306-1,ZFIN:ZDB-MRPHLNO-140306-2	Zfish	PMID:23656588
Biological Process	GO:0021549	cerebellum development	rnf216	IMP	ZFIN:ZDB-MRPHLNO-140306-1	Zfish	PMID:23656588
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	RNF216	IDA		Human	PMID:19893624
Biological Process	GO:0099546	protein catabolic process, modulating synaptic transmission	Rnf216	IDA		Rat	PMID:24945773|RGD:11553202
Biological Process	GO:0099546	protein catabolic process, modulating synaptic transmission	Rnf216	IMP		Rat	PMID:24945773|RGD:11553202
Biological Process	GO:0070936	protein K48-linked ubiquitination	RNF216	IDA		Human	PMID:19893624
Biological Process	GO:0050691	regulation of defense response to virus by host	RNF216	IDA		Human	PMID:19893624
Biological Process	GO:0032648	regulation of interferon-beta production	RNF216	IDA		Human	PMID:19893624
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Rnf216	IDA		Rat	PMID:24945773|RGD:11553202
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Rnf216	IMP		Rat	PMID:24945773|RGD:11553202

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern