Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF220
  • Mouse genes Rnf220
  • Rat genes Rnf220
  • Zfish genes rnf220a,rnf220b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf220

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	RNF220	IMP		Human	PMID:33964137
Molecular Function	GO:0005515	protein binding	RNF220	IPI	UniProtKB:P35222	Human	PMID:25266658
Molecular Function	GO:0005515	protein binding	RNF220	IPI	UniProtKB:Q93009	Human	PMID:25266658
Molecular Function	GO:0005515	protein binding	RNF220	IPI	UniProtKB:A6NMT0	Human	PMID:30177510
Molecular Function	GO:0005515	protein binding	RNF220	IPI	UniProtKB:O95096	Human	PMID:30177510
Molecular Function	GO:0005515	protein binding	RNF220	IPI	UniProtKB:Q6ZNG2	Human	PMID:30177510
Molecular Function	GO:0005515	protein binding	RNF220	IPI	UniProtKB:Q96NZ1	Human	PMID:30177510
Molecular Function	GO:0005515	protein binding	RNF220	IPI	UniProtKB:Q9NQZ6	Human	PMID:30177510
Molecular Function	GO:0005515	protein binding	RNF220	IPI	UniProtKB:P35222	Human	PMID:33964137
Molecular Function	GO:0005515	protein binding	Rnf220	IPI	UniProtKB:Q62141	Mouse	MGI:MGI:4820696|PMID:20170641
Molecular Function	GO:0005515	protein binding	Rnf220	IPI	PR:Q68FG0	Mouse	PMID:32094113
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Rnf220	IDA		Mouse	PMID:20170641
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Rnf220	IDA		Mouse	MGI:MGI:4820696|PMID:20170641
Cellular Component	GO:0005737	cytoplasm	Rnf220	IDA		Mouse	MGI:MGI:4820696|PMID:20170641
Cellular Component	GO:0005652	nuclear lamina	RNF220	IMP		Human	PMID:33964137
Cellular Component	GO:0005634	nucleus	RNF220	IMP		Human	PMID:33964137
Cellular Component	GO:0032991	protein-containing complex	RNF220	IDA		Human	PMID:30177510
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Rnf220	IMP	MGI:MGI:6393918	Mouse	PMID:30177510
Biological Process	GO:0003358	noradrenergic neuron development	Rnf220	IMP	MGI:MGI:6451114	Mouse	PMID:32094113
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	RNF220	IMP		Human	PMID:25266658
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	RNF220	IGI	UniProtKB:Q9NQZ6	Human	PMID:32094113
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	Rnf220	IGI	MGI:MGI:2679294	Mouse	PMID:32094113
Biological Process	GO:0051865	protein autoubiquitination	Rnf220	IDA		Mouse	MGI:MGI:4820696|PMID:20170641
Biological Process	GO:0006513	protein monoubiquitination	RNF220	IGI	UniProtKB:Q9NQZ6	Human	PMID:32094113
Biological Process	GO:0006513	protein monoubiquitination	Rnf220	IGI	MGI:MGI:2679294	Mouse	PMID:32094113
Biological Process	GO:0016567	protein ubiquitination	Rnf220	IDA		Mouse	MGI:MGI:4820696|PMID:20170641
Biological Process	GO:2000677	regulation of transcription regulatory region DNA binding	RNF220	IGI	UniProtKB:Q9NQZ6	Human	PMID:32094113
Biological Process	GO:2000677	regulation of transcription regulatory region DNA binding	Rnf220	IGI	MGI:MGI:2679294	Mouse	PMID:32094113
Biological Process	GO:0021511	spinal cord patterning	rnf220a	IMP	ZFIN:ZDB-GENO-210131-1	Zfish	PMID:31336385

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern