Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF40
  • Mouse genes Rnf40
  • Rat genes Rnf40
  • Zfish genes rnf40
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf40

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003730	mRNA 3'-UTR binding	RNF40	IDA		Human	PMID:19575011
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:P06400	Human	PMID:10944455
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q09161	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q5VTR2	Human	PMID:16307923
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q5VTR2	Human	PMID:19410543
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q9BTA9	Human	PMID:21329877
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q7KZS0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q86XK3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q8IYE0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q9Y2J4-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q6FHY5	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q09161	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q68J44	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q6PEW1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q7KZS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q9NRI5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:Q9Y2J4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF40	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Rnf40	IPI	PR:Q5DTM8	Mouse	PMID:22252316
Molecular Function	GO:0005515	protein binding	Rnf40	IPI	UniProtKB:O14933	Rat	PMID:12121982|RGD:633892
Molecular Function	GO:0005515	protein binding	Rnf40	IPI	UniProtKB:P61265	Rat	PMID:12121982|RGD:633892
Molecular Function	GO:0042803	protein homodimerization activity	RNF40	IPI	UniProtKB:O75150	Human	PMID:10944455
Molecular Function	GO:0017075	syntaxin-1 binding	Rnf40	IPI	RGD:3784	Rat	PMID:12121982|RGD:633892
Molecular Function	GO:0031624	ubiquitin conjugating enzyme binding	Rnf40	IDA		Rat	PMID:12121982|RGD:633892
Molecular Function	GO:0031625	ubiquitin protein ligase binding	RNF40	IPI	UniProtKB:Q5VTR2	Human	PMID:16307923
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF40	IDA		Human	PMID:16307923
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Rnf40	IDA		Rat	PMID:12121982|RGD:633892
Cellular Component	GO:0033503	HULC complex	RNF40	IDA		Human	PMID:19410543
Cellular Component	GO:0016020	membrane	RNF40	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Rnf40	IDA		Rat	PMID:12121982|RGD:633892
Cellular Component	GO:0005654	nucleoplasm	RNF40	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RNF40	IDA		Human	PMID:10944455
Cellular Component	GO:0005634	nucleus	RNF40	IDA		Human	PMID:16307923
Cellular Component	GO:0032991	protein-containing complex	Rnf40	IDA		Rat	PMID:12121982|RGD:633892
Cellular Component	GO:0000151	ubiquitin ligase complex	RNF40	IDA		Human	PMID:16307923
Biological Process	GO:1901800	positive regulation of proteasomal protein catabolic process	Rnf40	IDA		Rat	PMID:12121982|RGD:633892
Biological Process	GO:1902916	positive regulation of protein polyubiquitination	Rnf40	IDA		Rat	PMID:12121982|RGD:633892
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	RNF40	IDA		Human	PMID:16307923
Biological Process	GO:0043434	response to peptide hormone	Rnf40	IEP		Rat	PMID:21734099|RGD:9587431
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Rnf40	IDA		Rat	PMID:12121982|RGD:633892

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern