Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF41
  • Mouse genes Rnf41
  • Rat genes Rnf41
  • Zfish genes rnf41
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf41

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005128	erythropoietin receptor binding	Rnf41	IDA		Mouse	PMID:18495327
Molecular Function	GO:0042802	identical protein binding	RNF41	IPI	UniProtKB:Q9H4P4	Human	PMID:22493164
Molecular Function	GO:0042802	identical protein binding	RNF41	IPI	UniProtKB:Q9H4P4	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	RNF41	IPI	UniProtKB:Q9H4P4	Human	PMID:31515488
Molecular Function	GO:0005135	interleukin-3 receptor binding	Rnf41	IDA		Mouse	PMID:18495327
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q15303	Human	PMID:11867753
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q9NR09	Human	PMID:14765125
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:O88738	Human	PMID:15314180
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q80U87	Human	PMID:15314180
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:P35249	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q99614	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:P35249	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q66PJ3-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q86U28	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q8N1B4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q99614	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q9NSB8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q9NWX5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q9NX04	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q7LG56	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:O15049	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q99614	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q9NWX5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q9UHY7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:A0A0C4DG62	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:O15049	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:P35249	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:P54725	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q86U28	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q8N1B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q8N3F0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q8N8B7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q99614	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q9GZT4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q9NWX5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q9NX04	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:Q9UHY7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF41	IPI	UniProtKB:P61086	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Rnf41	IPI	UniProtKB:Q80U87	Mouse	MGI:MGI:3054509|PMID:15314180
Molecular Function	GO:0005515	protein binding	Rnf41	IPI	UniProtKB:Q80U30-2	Mouse	MGI:MGI:5603233|PMID:24949970
Molecular Function	GO:0005515	protein binding	Rnf41	IPI	PR:Q99P72	Mouse	PMID:18986647
Molecular Function	GO:0005515	protein binding	Rnf41	IPI	PR:P28033	Mouse	PMID:22707723
Molecular Function	GO:0019904	protein domain specific binding	RNF41	IPI	UniProtKB:Q9NQC3	Human	PMID:27353365
Molecular Function	GO:0030971	receptor tyrosine kinase binding	RNF41	IPI	UniProtKB:P21860	Human	PMID:27353365
Molecular Function	GO:0031267	small GTPase binding	RNF41	IPI	UniProtKB:P11233	Human	PMID:24056301
Molecular Function	GO:0031267	small GTPase binding	RNF41	IPI	UniProtKB:P11234	Human	PMID:24056301
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF41	IDA		Human	PMID:18541373
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF41	IDA		Human	PMID:14765125
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF41	IDA		Human	PMID:18541373
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF41	IDA		Human	PMID:24105792
Cellular Component	GO:0071782	endoplasmic reticulum tubular network	RNF41	IDA		Human	PMID:27353365
Cellular Component	GO:0048471	perinuclear region of cytoplasm	RNF41	IDA		Human	PMID:27353365
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	RNF41	IDA		Human	PMID:14765125
Biological Process	GO:0030318	melanocyte differentiation	rnf41	IMP	ZFIN:ZDB-MRPHLNO-110810-3	Zfish	PMID:21596016
Biological Process	GO:0030336	negative regulation of cell migration	RNF41	IMP		Human	PMID:17145873
Biological Process	GO:0008285	negative regulation of cell population proliferation	RNF41	IDA		Human	PMID:17145873
Biological Process	GO:1901525	negative regulation of mitophagy	Rnf41	IGI	MGI:MGI:1921624	Mouse	PMID:24949970
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	Rnf41	IDA		Mouse	PMID:22707723
Biological Process	GO:0045732	positive regulation of protein catabolic process	RNF41	IMP		Human	PMID:27353365
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	RNF41	IMP		Human	PMID:18541373
Biological Process	GO:0010498	proteasomal protein catabolic process	RNF41	IDA		Human	PMID:18541373
Biological Process	GO:0051865	protein autoubiquitination	RNF41	IDA		Human	PMID:24105792
Biological Process	GO:0000209	protein polyubiquitination	RNF41	IDA		Human	PMID:14765125
Biological Process	GO:0000209	protein polyubiquitination	RNF41	IDA		Human	PMID:18541373
Biological Process	GO:0000209	protein polyubiquitination	Rnf41	IDA		Mouse	PMID:18495327
Biological Process	GO:0016567	protein ubiquitination	Rnf41	IDA		Mouse	PMID:22707723
Biological Process	GO:2000114	regulation of establishment of cell polarity	Rnf41	IDA		Mouse	PMID:22707723
Biological Process	GO:0010468	regulation of gene expression	Rnf41	IDA		Mouse	PMID:22707723
Biological Process	GO:0045619	regulation of lymphocyte differentiation	Rnf41	IDA		Mouse	PMID:18495327
Biological Process	GO:0043408	regulation of MAPK cascade	RNF41	IDA		Human	PMID:17145873
Biological Process	GO:0045637	regulation of myeloid cell differentiation	Rnf41	IDA		Mouse	PMID:18495327
Biological Process	GO:0051896	regulation of protein kinase B signaling	RNF41	IDA		Human	PMID:17145873
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	RNF41	IMP		Human	PMID:18541373

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern