Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF5
  • Mouse genes Rnf5
  • Rat genes Rnf5
  • Zfish genes rnf5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	RNF5	IPI	UniProtKB:Q99942	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	RNF5	IPI	UniProtKB:Q99942	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P49023	Human	PMID:12861019
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:O95870	Human	PMID:14667819
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P61077	Human	PMID:14667819
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P62837	Human	PMID:14667819
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q969T4	Human	PMID:14667819
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P13569	Human	PMID:16901789
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9P055	Human	PMID:19269966
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P51668	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P61077	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P62837	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q969T4	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q96B02	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q96LR5	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9Y2X8	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P62837	Human	PMID:20152160
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:O94905	Human	PMID:24019521
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:O95870	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P43005	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P49447	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P51668	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P61077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P61086	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q8NBI2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q969T4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q96B02	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q96FI0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q96GF1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q96IW7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q96LR5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9BWQ6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9NVC3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9NWH2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9Y2X8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9Y5U4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q15758	Human	PMID:25759021
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q96QD8	Human	PMID:25759021
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q969T4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:A0PK00	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:O00767	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:O60831	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:O95214	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:O95870	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P11836	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P43005	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P51668	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P61077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P61086	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P62837	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q04941	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q15041	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q5VVQ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q6UX98	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q6ZPD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q7Z769	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q8IY26	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q8N138	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q8NBI2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q8TEB9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q969T4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q96D05-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q96GQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q96LR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9BSR8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9BWQ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9HAC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9NVC3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9P0S3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9UI14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9Y2X8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9Y548	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q9Y5U4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:P61086	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RNF5	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Rnf5	IPI	PR:Q8BGE6	Mouse	PMID:23093945
Molecular Function	GO:0044877	protein-containing complex binding	RNF5	IPI	UniProtKB:Q9BUN8	Human	PMID:24019521
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF5	IDA		Human	PMID:19269966
Cellular Component	GO:0005783	endoplasmic reticulum	RNF5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Rnf5	IDA		Mouse	PMID:23093945
Biological Process	GO:0071712	ER-associated misfolded protein catabolic process	RNF5	IMP		Human	PMID:19269966
Biological Process	GO:0036503	ERAD pathway	RNF5	IMP		Human	PMID:24019521
Biological Process	GO:0010507	negative regulation of autophagy	Rnf5	IMP	MGI:MGI:3775796	Mouse	PMID:23093945
Biological Process	GO:0030163	protein catabolic process	RNF5	IMP		Human	PMID:19285439
Biological Process	GO:0031648	protein destabilization	Rnf5	IDA		Mouse	PMID:23093945
Biological Process	GO:0070936	protein K48-linked ubiquitination	RNF5	IDA		Human	PMID:19285439
Biological Process	GO:0070534	protein K63-linked ubiquitination	RNF5	IDA		Human	PMID:19269966
Biological Process	GO:0016567	protein ubiquitination	Rnf5	IDA		Mouse	PMID:23093945
Biological Process	GO:2000785	regulation of autophagosome assembly	Rnf5	IMP	MGI:MGI:3775796	Mouse	PMID:23093945
Biological Process	GO:0009617	response to bacterium	Rnf5	IMP		Mouse	PMID:23093945
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	RNF5	IGI	UniProtKB:Q96GF1	Human	PMID:24019521

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern