Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNLS
  • Mouse genes Rnls
  • Rat genes Rnls
  • Zfish genes rnls
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnls

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051379	epinephrine binding	RNLS	IDA		Human	PMID:23964689
Molecular Function	GO:0097621	monoamine oxidase activity	RNLS	IMP		Human	PMID:15841207
Molecular Function	GO:0070404	NADH binding	RNLS	IDA		Human	PMID:25531177
Molecular Function	GO:0016491	oxidoreductase activity	Rnls	IDA		Mouse	PMID:21178975
Molecular Function	GO:0016651	oxidoreductase activity, acting on NAD(P)H	RNLS	IDA		Human	PMID:23964689
Molecular Function	GO:0016651	oxidoreductase activity, acting on NAD(P)H	RNLS	IDA		Human	PMID:25531177
Molecular Function	GO:0005515	protein binding	RNLS	IPI	UniProtKB:P23634	Human	PMID:25906147
Cellular Component	GO:0005576	extracellular region	RNLS	IDA		Human	PMID:15841207
Cellular Component	GO:0005615	extracellular space	Rnls	IDA		Rat	PMID:23314744|RGD:7327156
Biological Process	GO:0003214	cardiac left ventricle morphogenesis	Rnls	IMP	MGI:MGI:5433853	Mouse	PMID:21178975
Biological Process	GO:0042417	dopamine metabolic process	Rnls	IMP	MGI:MGI:5433853	Mouse	PMID:21178975
Biological Process	GO:0042414	epinephrine metabolic process	Rnls	IMP	MGI:MGI:5433853	Mouse	PMID:21178975
Biological Process	GO:0060047	heart contraction	Rnls	IMP	MGI:MGI:5433853	Mouse	PMID:21178975
Biological Process	GO:0045776	negative regulation of blood pressure	RNLS	IDA		Human	PMID:15841207
Biological Process	GO:0010459	negative regulation of heart rate	RNLS	IDA		Human	PMID:15841207
Biological Process	GO:0042415	norepinephrine metabolic process	Rnls	IMP	MGI:MGI:5433853	Mouse	PMID:21178975
Biological Process	GO:0055062	phosphate ion homeostasis	Rnls	IMP	MGI:MGI:5433853	Mouse	PMID:23863468
Biological Process	GO:0003073	regulation of systemic arterial blood pressure	Rnls	IMP	MGI:MGI:5433853	Mouse	PMID:21178975
Biological Process	GO:0071869	response to catecholamine	Rnls	IEP		Rat	PMID:18299506|RGD:7327164
Biological Process	GO:0071871	response to epinephrine	Rnls	IEP		Rat	PMID:18299506|RGD:7327164
Biological Process	GO:0002931	response to ischemia	Rnls	IEP		Rat	PMID:21297953|RGD:7327162
Biological Process	GO:0071873	response to norepinephrine	Rnls	IMP	MGI:MGI:5433853	Mouse	PMID:21178975
Biological Process	GO:1902074	response to salt	Rnls	IDA		Rat	PMID:23314744|RGD:7327156

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern