Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ROBO3
  • Mouse genes Robo3
  • Rat genes Robo3
  • Zfish genes robo3,zgc:77784
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Robo3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ROBO3	IPI	UniProtKB:Q99435-1	Human	PMID:26586761
Molecular Function	GO:0005515	protein binding	Robo3	IPI	UniProtKB:O94813	Mouse	PMID:15084255
Molecular Function	GO:0005515	protein binding	robo3	IPI	UniProtKB:A8BBD5	Zfish	PMID:19765300
Cellular Component	GO:0030424	axon	Robo3	IDA		Mouse	PMID:19906978
Cellular Component	GO:0005886	plasma membrane	robo3	IDA		Zfish	PMID:16129585
Biological Process	GO:0048675	axon extension	robo3	IMP	ZFIN:ZDB-MRPHLNO-051031-1	Zfish	PMID:16129585
Biological Process	GO:0007411	axon guidance	Robo3	IDA		Mouse	MGI:MGI:6316558|PMID:30843071
Biological Process	GO:0007411	axon guidance	Robo3	IMP	MGI:MGI:3043150	Mouse	PMID:15233918
Biological Process	GO:0007411	axon guidance	Robo3	IMP	MGI:MGI:3043150	Mouse	PMID:15084255
Biological Process	GO:0007411	axon guidance	Robo3	IGI	MGI:MGI:1274781	Mouse	PMID:15084255
Biological Process	GO:0007411	axon guidance	Robo3	IDA		Mouse	PMID:15084255
Biological Process	GO:0007411	axon guidance	robo3	IGI	ZFIN:ZDB-MRPHLNO-080708-11,ZFIN:ZDB-MRPHLNO-080708-13,ZFIN:ZDB-MRPHLNO-080708-7	Zfish	PMID:18061159
Biological Process	GO:0007411	axon guidance	robo3	IMP	ZFIN:ZDB-MRPHLNO-080708-11	Zfish	PMID:18061159
Biological Process	GO:0007411	axon guidance	robo3	IMP	ZFIN:ZDB-GENO-980202-1088	Zfish	PMID:23222439
Biological Process	GO:0016199	axon midline choice point recognition	Robo3	IMP		Mouse	MGI:MGI:3823169|PMID:18986510
Biological Process	GO:0016199	axon midline choice point recognition	robo3	IMP	ZFIN:ZDB-GENO-980202-1088	Zfish	PMID:19496826
Biological Process	GO:0016199	axon midline choice point recognition	robo3	IMP	ZFIN:ZDB-GENO-980202-1515	Zfish	PMID:19496826
Biological Process	GO:0071679	commissural neuron axon guidance	robo3	IMP	ZFIN:ZDB-GENO-980202-1515	Zfish	PMID:19496826
Biological Process	GO:0071679	commissural neuron axon guidance	robo3	IMP	ZFIN:ZDB-GENO-980202-1088	Zfish	PMID:19496826
Biological Process	GO:0048264	determination of ventral identity	robo3	IMP	ZFIN:ZDB-MRPHLNO-051031-1	Zfish	PMID:16129585
Biological Process	GO:0001764	neuron migration	Robo3	IMP	MGI:MGI:3043150	Mouse	PMID:15233918

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern