Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ROR1
  • Mouse genes Ror1
  • Rat genes Ror1
  • Zfish genes ror1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ror1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ROR1	IPI	UniProtKB:P00533	Human	PMID:22439932
Molecular Function	GO:0005515	protein binding	ROR1	IPI	UniProtKB:P05480	Human	PMID:22439932
Molecular Function	GO:0005515	protein binding	ROR1	IPI	UniProtKB:P12931	Human	PMID:22439932
Molecular Function	GO:0042813	Wnt receptor activity	ROR1	IMP		Human	PMID:27162350
Molecular Function	GO:0017147	Wnt-protein binding	ROR1	IPI	UniProtKB:P41221	Human	PMID:18287027
Cellular Component	GO:0043679	axon terminus	Ror1	IDA		Mouse	MGI:MGI:5776284|PMID:27162350
Cellular Component	GO:0009986	cell surface	Ror1	IDA		Rat	PMID:15095375|RGD:11537371
Cellular Component	GO:0005737	cytoplasm	Ror1	IDA		Rat	PMID:15095375|RGD:11537371
Cellular Component	GO:0005886	plasma membrane	ROR1	IDA		Human	PMID:27162350
Cellular Component	GO:0043235	receptor complex	ROR1	IDA		Human	PMID:23382219
Cellular Component	GO:0001725	stress fiber	Ror1	IDA		Rat	PMID:15095375|RGD:11537371
Biological Process	GO:0014002	astrocyte development	Ror1	IDA		Rat	PMID:15095375|RGD:11537371
Biological Process	GO:0048839	inner ear development	Ror1	IMP		Mouse	MGI:MGI:5776284|PMID:27162350
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ROR1	IMP		Human	PMID:27162350
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ROR1	IMP		Human	PMID:27162350
Biological Process	GO:0007605	sensory perception of sound	ROR1	IMP		Human	PMID:27162350

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern