Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RORB
  • Mouse genes Rorb
  • Rat genes Rorb
  • Zfish genes rorb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rorb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Rorb	IDA		Mouse	MGI:MGI:3652638|PMID:16574740
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Rorb	IDA		Mouse	MGI:MGI:3652638|PMID:16574740
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Rorb	IDA		Rat	PMID:12958591|RGD:8553609
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Rorb	IDA		Rat	PMID:7961794|RGD:2314873
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Rorb	IDA		Rat	PMID:9729429|RGD:8554235
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Rorb	IDA		Mouse	MGI:MGI:5546314|PMID:23652001
Molecular Function	GO:0008502	melatonin receptor activity	Rorb	IDA		Rat	PMID:7961794|RGD:2314873
Molecular Function	GO:0005515	protein binding	RORB	IPI	UniProtKB:O08785	Human	PMID:23555304
Molecular Function	GO:0005515	protein binding	Rorb	IPI	UniProtKB:O54751	Mouse	MGI:MGI:3652638|PMID:16574740
Molecular Function	GO:0005515	protein binding	Rorb	IPI	PR:Q9JHR9	Mouse	PMID:10860982
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Rorb	IDA		Mouse	MGI:MGI:3652638|PMID:16574740
Molecular Function	GO:0043565	sequence-specific DNA binding	Rorb	IDA		Mouse	MGI:MGI:3652638|PMID:16574740
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	RORB	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	RORB	IDA		Human	PMID:27352968
Cellular Component	GO:0005634	nucleus	Rorb	IDA		Mouse	MGI:MGI:3652638|PMID:16574740
Biological Process	GO:0035881	amacrine cell differentiation	Rorb	IMP		Mouse	MGI:MGI:5546314|PMID:23652001
Biological Process	GO:0007420	brain development	Rorb	IEP		Rat	PMID:8905729|RGD:2314872
Biological Process	GO:0071300	cellular response to retinoic acid	Rorb	IDA		Rat	PMID:12958591|RGD:8553609
Biological Process	GO:0007623	circadian rhythm	Rorb	IEP		Rat	PMID:15781226|RGD:2325957
Biological Process	GO:0007623	circadian rhythm	Rorb	IEP		Rat	PMID:18321474|RGD:2301031
Biological Process	GO:0042462	eye photoreceptor cell development	Rorb	IMP		Mouse	MGI:MGI:3652638|PMID:16574740
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Rorb	IDA		Rat	PMID:9729429|RGD:8554235
Biological Process	GO:0045668	negative regulation of osteoblast differentiation	Rorb	IDA		Mouse	MGI:MGI:5554363|PMID:22189870
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Rorb	IDA		Mouse	MGI:MGI:3652638|PMID:16574740
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Rorb	IDA		Rat	PMID:12958591|RGD:8553609
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Rorb	IDA		Rat	PMID:9729429|RGD:8554235
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Rorb	IDA		Mouse	MGI:MGI:5546314|PMID:23652001
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Rorb	IDA		Mouse	MGI:MGI:3652638|PMID:16574740
Biological Process	GO:0042752	regulation of circadian rhythm	Rorb	IMP		Mouse	MGI:MGI:3712731|PMID:17303680
Biological Process	GO:0009725	response to hormone	Rorb	IEP		Rat	PMID:17067745|RGD:2314871
Biological Process	GO:0060041	retina development in camera-type eye	Rorb	IMP		Mouse	MGI:MGI:5546314|PMID:23652001
Biological Process	GO:0046549	retinal cone cell development	Rorb	IDA		Mouse	MGI:MGI:3652638|PMID:16574740
Biological Process	GO:0046548	retinal rod cell development	Rorb	IMP		Mouse	MGI:MGI:3652638|PMID:16574740
Biological Process	GO:0046548	retinal rod cell development	Rorb	IMP		Mouse	MGI:MGI:4366105|PMID:19805139
Biological Process	GO:0060221	retinal rod cell differentiation	Rorb	IMP	MGI:MGI:2158692	Mouse	PMID:25296752

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern