Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ROS1
  • Mouse genes Ros1
  • Rat genes Ros1
  • Zfish genes ros1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ros1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ROS1	IPI	UniProtKB:P18031	Human	PMID:17416557
Molecular Function	GO:0005515	protein binding	ROS1	IPI	UniProtKB:P29350	Human	PMID:17416557
Molecular Function	GO:0005515	protein binding	ROS1	IPI	UniProtKB:Q99435	Human	PMID:32499443
Molecular Function	GO:0019903	protein phosphatase binding	ROS1	IPI	UniProtKB:P35235	Human	PMID:16885344
Molecular Function	GO:0019903	protein phosphatase binding	Ros1	IPI	UniProtKB:P29350	Mouse	MGI:MGI:1930880|PMID:11266449
Molecular Function	GO:0004713	protein tyrosine kinase activity	ROS1	IDA		Human	PMID:16885344
Cellular Component	GO:0009986	cell surface	Ros1	IDA		Mouse	PMID:7970722
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ros1	IDA		Mouse	PMID:7970722
Biological Process	GO:0030154	cell differentiation	Ros1	IDA		Mouse	MGI:MGI:1930880|PMID:11266449
Biological Process	GO:0002066	columnar/cuboidal epithelial cell development	Ros1	IMP		Mouse	MGI:MGI:80739|PMID:8675006
Biological Process	GO:0010467	gene expression	Ros1	IMP	MGI:MGI:2450566	Mouse	PMID:12399522
Biological Process	GO:0010629	negative regulation of gene expression	Ros1	IMP	MGI:MGI:2450566	Mouse	PMID:12773415
Biological Process	GO:0038083	peptidyl-tyrosine autophosphorylation	Ros1	IDA		Mouse	PMID:7970722
Biological Process	GO:0006468	protein phosphorylation	ROS1	IDA		Human	PMID:16885344
Biological Process	GO:0006468	protein phosphorylation	Ros1	IDA		Mouse	MGI:MGI:1930880|PMID:11266449
Biological Process	GO:0001558	regulation of cell growth	ROS1	IDA		Human	PMID:16885344
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	Ros1	IDA		Mouse	MGI:MGI:1930880|PMID:11266449
Biological Process	GO:0010966	regulation of phosphate transport	Ros1	IMP	MGI:MGI:2450566	Mouse	PMID:12773415
Biological Process	GO:0032006	regulation of TOR signaling	ROS1	IDA		Human	PMID:16885344
Biological Process	GO:0007165	signal transduction	Ros1	IDA		Mouse	PMID:7854358
Biological Process	GO:0007283	spermatogenesis	Ros1	IMP		Mouse	MGI:MGI:80739|PMID:8675006
Biological Process	GO:0007283	spermatogenesis	Ros1	IMP	MGI:MGI:2450566	Mouse	PMID:12773415

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern