Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RP2
  • Mouse genes Rp2
  • Rat genes Rp2
  • Zfish genes rp2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	RP2	IDA		Human	PMID:11847227
Molecular Function	GO:0005096	GTPase activator activity	RP2	IDA		Human	PMID:18376416
Molecular Function	GO:0005096	GTPase activator activity	RP2	IDA		Human	PMID:26455799
Molecular Function	GO:0000287	magnesium ion binding	RP2	IDA		Human	PMID:26455799
Molecular Function	GO:0005515	protein binding	RP2	IPI	UniProtKB:P36405	Human	PMID:11847227
Molecular Function	GO:0005515	protein binding	RP2	IPI	UniProtKB:Q9WUL7	Human	PMID:16472755
Molecular Function	GO:0005515	protein binding	RP2	IPI	UniProtKB:Q9WUL7	Human	PMID:18376416
Molecular Function	GO:0005515	protein binding	RP2	IPI	UniProtKB:Q9WUL7	Human	PMID:26455799
Molecular Function	GO:0005515	protein binding	RP2	IPI	UniProtKB:Q8IYS1	Human	PMID:32296183
Cellular Component	GO:0005814	centriole	Rp2	IDA		Mouse	PMID:20106869
Cellular Component	GO:0036064	ciliary basal body	RP2	IDA		Human	PMID:20106869
Cellular Component	GO:0036064	ciliary basal body	RP2	IDA		Human	PMID:26455799
Cellular Component	GO:0036064	ciliary basal body	Rp2	IDA		Mouse	PMID:20106869
Cellular Component	GO:0005737	cytoplasm	RP2	IDA		Human	PMID:12417528
Cellular Component	GO:0031410	cytoplasmic vesicle	RP2	IGI	UniProtKB:P36405	Human	PMID:20106869
Cellular Component	GO:0070062	extracellular exosome	RP2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	RP2	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	RP2	HDA		Human	PMID:23533145
Cellular Component	GO:0005794	Golgi apparatus	Rp2	IDA		Mouse	PMID:20106869
Cellular Component	GO:0016604	nuclear body	RP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	RP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:1990075	periciliary membrane compartment	Rp2	IDA		Mouse	PMID:20106869
Cellular Component	GO:0005886	plasma membrane	RP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	RP2	IDA		Human	PMID:12417528
Cellular Component	GO:0005886	plasma membrane	RP2	IDA		Human	PMID:20106869
Cellular Component	GO:0005886	plasma membrane	Rp2	IDA		Mouse	PMID:20106869
Biological Process	GO:0061371	determination of heart left/right asymmetry	rp2	IMP	ZFIN:ZDB-MRPHLNO-101122-1	Zfish	PMID:26134862
Biological Process	GO:0001947	heart looping	rp2	IMP	ZFIN:ZDB-MRPHLNO-101122-2	Zfish	PMID:20729296
Biological Process	GO:0001947	heart looping	rp2	IMP	ZFIN:ZDB-MRPHLNO-101122-1	Zfish	PMID:26134862
Biological Process	GO:0042461	photoreceptor cell development	rp2	IMP	ZFIN:ZDB-MRPHLNO-110725-3	Zfish	PMID:21738648
Biological Process	GO:0045494	photoreceptor cell maintenance	rp2	IMP	ZFIN:ZDB-GENO-170615-12	Zfish	PMID:28209709
Biological Process	GO:0035845	photoreceptor cell outer segment organization	rp2	IMP	ZFIN:ZDB-MRPHLNO-110725-3	Zfish	PMID:21738648
Biological Process	GO:0006892	post-Golgi vesicle-mediated transport	RP2	IGI	UniProtKB:P36405	Human	PMID:20106869
Biological Process	GO:0006892	post-Golgi vesicle-mediated transport	RP2	IMP		Human	PMID:20106869
Biological Process	GO:0048793	pronephros development	rp2	IMP	ZFIN:ZDB-MRPHLNO-101122-2	Zfish	PMID:20729296
Biological Process	GO:0048793	pronephros development	rp2	IGI	ZFIN:ZDB-MRPHLNO-060630-4,ZFIN:ZDB-MRPHLNO-101122-2	Zfish	PMID:20729296
Biological Process	GO:0060041	retina development in camera-type eye	rp2	IMP	ZFIN:ZDB-MRPHLNO-120222-8	Zfish	PMID:21282572
Biological Process	GO:0010842	retina layer formation	rp2	IMP	ZFIN:ZDB-MRPHLNO-120222-8	Zfish	PMID:21282572

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern