Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RPA1
  • Mouse genes Rpa1
  • Rat genes Rpa1
  • Zfish genes rpa1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rpa1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Rpa1	IDA		Mouse	PMID:12091911
Molecular Function	GO:0003684	damaged DNA binding	RPA1	IDA		Human	PMID:27723717
Molecular Function	GO:0003684	damaged DNA binding	RPA1	IDA		Human	PMID:27723720
Molecular Function	GO:0003684	damaged DNA binding	RPA1	IDA		Human	PMID:7700386
Molecular Function	GO:0098505	G-rich strand telomeric DNA binding	RPA1	IDA		Human	PMID:16973897
Molecular Function	GO:0098505	G-rich strand telomeric DNA binding	RPA1	IDA		Human	PMID:24747047
Molecular Function	GO:0098505	G-rich strand telomeric DNA binding	RPA1	IMP		Human	PMID:26041456
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q14191	Human	PMID:10373438
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P54132	Human	PMID:10825162
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P15927	Human	PMID:11927569
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P35244	Human	PMID:11927569
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P15927	Human	PMID:12527904
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P35244	Human	PMID:12527904
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P03070	Human	PMID:1311258
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P09884	Human	PMID:1311258
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q14191	Human	PMID:15735006
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P54132	Human	PMID:15775963
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q99638	Human	PMID:15897895
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P15927	Human	PMID:15965237
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P54132	Human	PMID:15965237
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q14191	Human	PMID:15965237
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P03070	Human	PMID:17666013
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P09884	Human	PMID:17666013
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P03070	Human	PMID:17673209
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P35244	Human	PMID:19338310
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P15927	Human	PMID:20811460
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P35244	Human	PMID:20811460
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P15927	Human	PMID:2159011
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P35244	Human	PMID:2159011
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P15927	Human	PMID:24126761
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P35244	Human	PMID:24126761
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P54132	Human	PMID:24126761
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q14191	Human	PMID:24126761
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q96LW4	Human	PMID:24126761
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P15927	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P35244	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P15927	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P35244	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q9NY74	Human	PMID:27723717
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q9NY74	Human	PMID:27723720
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q13156	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q96LW4	Human	PMID:28534480
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q7Z7L1	Human	PMID:29395061
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P15927	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P17066	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P15927	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P23025	Human	PMID:7700386
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P15927	Human	PMID:7760808
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:P35244	Human	PMID:7760808
Molecular Function	GO:0005515	protein binding	RPA1	IPI	UniProtKB:Q13156	Human	PMID:7760808
Molecular Function	GO:0003697	single-stranded DNA binding	RPA1	IDA		Human	PMID:19010961
Molecular Function	GO:0003697	single-stranded DNA binding	RPA1	IDA		Human	PMID:8990123
Molecular Function	GO:0003697	single-stranded DNA binding	Rpa1	IDA		Rat	PMID:8463251|RGD:2307012
Cellular Component	GO:0000781	chromosome, telomeric region	RPA1	HDA		Human	PMID:19135898
Cellular Component	GO:0000793	condensed chromosome	Rpa1	IDA		Mouse	PMID:12091911
Cellular Component	GO:0000794	condensed nuclear chromosome	Rpa1	IDA		Mouse	PMID:20551173
Cellular Component	GO:0000794	condensed nuclear chromosome	Rpa1	IDA		Mouse	PMID:22164254
Cellular Component	GO:0000794	condensed nuclear chromosome	Rpa1	IDA		Mouse	PMID:18283110
Cellular Component	GO:0000794	condensed nuclear chromosome	Rpa1	IDA		Mouse	PMID:18316482
Cellular Component	GO:0005662	DNA replication factor A complex	RPA1	IPI		Human	PMID:11927569
Cellular Component	GO:0005662	DNA replication factor A complex	RPA1	IPI		Human	PMID:7760808
Cellular Component	GO:0005662	DNA replication factor A complex	RPA1	IDA		Human	PMID:11927569
Cellular Component	GO:0005662	DNA replication factor A complex	RPA1	IDA		Human	PMID:27723717
Cellular Component	GO:0005662	DNA replication factor A complex	RPA1	IDA		Human	PMID:27723720
Cellular Component	GO:0005662	DNA replication factor A complex	Rpa1	IDA		Rat	PMID:7503737|RGD:2307013
Cellular Component	GO:0005662	DNA replication factor A complex	Rpa1	IDA		Rat	PMID:8463251|RGD:2307012
Cellular Component	GO:0000800	lateral element	Rpa1	IDA		Mouse	PMID:21743440
Cellular Component	GO:0000800	lateral element	Rpa1	IDA		Mouse	PMID:22711701
Cellular Component	GO:0001673	male germ cell nucleus	Rpa1	IDA		Mouse	PMID:17696610
Cellular Component	GO:0005654	nucleoplasm	RPA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RPA1	IDA		Human	PMID:17959650
Cellular Component	GO:0005634	nucleus	Rpa1	IDA		Mouse	PMID:11555636
Cellular Component	GO:0016605	PML body	RPA1	IDA		Human	PMID:17959650
Cellular Component	GO:0016605	PML body	RPA1	IDA		Human	PMID:16135809
Cellular Component	GO:0090734	site of DNA damage	RPA1	IMP		Human	PMID:27248496
Biological Process	GO:0006284	base-excision repair	RPA1	IDA		Human	PMID:9765279
Biological Process	GO:0051276	chromosome organization	Rpa1	IMP	MGI:MGI:3582609	Mouse	PMID:15965476
Biological Process	GO:0006974	DNA damage response	RPA1	IMP		Human	PMID:27248496
Biological Process	GO:0006281	DNA repair	RPA1	IMP		Human	PMID:18469000
Biological Process	GO:0006281	DNA repair	RPA1	IDA		Human	PMID:20545304
Biological Process	GO:0006260	DNA replication	RPA1	IMP		Human	PMID:9430682
Biological Process	GO:0000724	double-strand break repair via homologous recombination	RPA1	IMP		Human	PMID:17765923
Biological Process	GO:0000724	double-strand break repair via homologous recombination	Rpa1	IMP	MGI:MGI:3582609	Mouse	PMID:15470499
Biological Process	GO:0007507	heart development	rpa1	IMP	ZFIN:ZDB-GENO-041007-12	Zfish	PMID:19652097
Biological Process	GO:0030097	hemopoiesis	Rpa1	IMP	MGI:MGI:3582609	Mouse	PMID:15965476
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Rpa1	IMP	MGI:MGI:3582609	Mouse	PMID:15965476
Biological Process	GO:0001701	in utero embryonic development	Rpa1	IMP	MGI:MGI:3582609	Mouse	PMID:15470499
Biological Process	GO:0051321	meiotic cell cycle	Rpa1	IDA		Mouse	PMID:12091911
Biological Process	GO:0006298	mismatch repair	RPA1	IMP		Human	PMID:9430682
Biological Process	GO:0006289	nucleotide-excision repair	RPA1	IMP		Human	PMID:9430682
Biological Process	GO:0008284	positive regulation of cell population proliferation	Rpa1	IMP	MGI:MGI:3582609	Mouse	PMID:15965476
Biological Process	GO:0034502	protein localization to chromosome	RPA1	IDA		Human	PMID:27723717
Biological Process	GO:0034502	protein localization to chromosome	RPA1	IDA		Human	PMID:27723720
Biological Process	GO:0000723	telomere maintenance	RPA1	IMP		Human	PMID:17959650

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern