Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RPGR
  • Mouse genes Rpgr
  • Rat genes Rpgr
  • Zfish genes rpgra,rpgrb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rpgr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RPGR	IPI	UniProtKB:Q68CZ1	Human	PMID:19430481
Molecular Function	GO:0005515	protein binding	RPGR	IPI	UniProtKB:O43924	Human	PMID:23559067
Molecular Function	GO:0005515	protein binding	RPGR	IPI	UniProtKB:Q96KN7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RPGR	IPI	UniProtKB:Q96KN7-4	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	RPGR	IPI	UniProtKB:Q96KN7	Human	PMID:26638075
Molecular Function	GO:0005515	protein binding	RPGR	IPI	UniProtKB:Q8IX15-3	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	RPGR	IPI	UniProtKB:Q96KN7	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	RPGR	IPI	UniProtKB:O43924	Human	PMID:30257685
Molecular Function	GO:0005515	protein binding	RPGR	IPI	UniProtKB:Q96KN7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RPGR	IPI	UniProtKB:O43924	Human	PMID:9990021
Molecular Function	GO:0005515	protein binding	RPGR	IPI	UniProtKB:O55057	Human	PMID:9990021
Molecular Function	GO:0005515	protein binding	Rpgr	IPI	UniProtKB:Q6A078	Mouse	MGI:MGI:3624140|PMID:16632484
Molecular Function	GO:0005515	protein binding	Rpgr	IPI	UniProtKB:Q80VW5-12	Mouse	MGI:MGI:5487507|PMID:22323458
Molecular Function	GO:0005515	protein binding	Rpgr	IPI	UniProtKB:O55057	Mouse	MGI:MGI:4887348|PMID:9990021
Molecular Function	GO:0005515	protein binding	Rpgr	IPI	UniProtKB:Q80VW5	Mouse	MGI:MGI:5487507|PMID:22323458
Molecular Function	GO:0005515	protein binding	Rpgr	IPI	UniProtKB:Q68CZ1	Mouse	MGI:MGI:6383266|PMID:19430481
Molecular Function	GO:0005515	protein binding	Rpgr	IPI	MGI:MGI:2144877	Mouse	PMID:29899041
Molecular Function	GO:0005515	protein binding	Rpgr	IPI	PR:Q9EPQ2	Mouse	PMID:11104772
Molecular Function	GO:0005515	protein binding	Rpgr	IPI	PR:P59240	Mouse	PMID:20664800
Molecular Function	GO:0003723	RNA binding	RPGR	HDA		Human	PMID:22658674
Cellular Component	GO:0042995	cell projection	Rpgr	IDA		Rat	PMID:20805823|RGD:8553230
Cellular Component	GO:0005813	centrosome	RPGR	IDA		Human	PMID:15772089
Cellular Component	GO:0036064	ciliary basal body	Rpgr	IDA		Mouse	MGI:MGI:3607627|PMID:16043481
Cellular Component	GO:0005929	cilium	Rpgr	IDA		Mouse	PMID:11104772
Cellular Component	GO:0005929	cilium	Rpgr	IDA		Mouse	PMID:12651948
Cellular Component	GO:0005929	cilium	Rpgr	IDA		Mouse	PMID:21212183
Cellular Component	GO:0005929	cilium	Rpgr	IDA		Rat	PMID:20805823|RGD:8553230
Cellular Component	GO:0005737	cytoplasm	Rpgr	IDA		Mouse	PMID:11104772
Cellular Component	GO:0005794	Golgi apparatus	RPGR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	Rpgr	IDA		Mouse	MGI:MGI:1276250|PMID:9677393
Cellular Component	GO:0032391	photoreceptor connecting cilium	Rpgr	IDA		Mouse	PMID:10725384
Cellular Component	GO:0120206	photoreceptor distal connecting cilium	Rpgr	IDA		Mouse	PMID:29899041
Cellular Component	GO:0001750	photoreceptor outer segment	RPGR	IDA		Human	PMID:12140192
Cellular Component	GO:0036126	sperm flagellum	Rpgr	IDA		Mouse	MGI:MGI:3607627|PMID:16043481
Biological Process	GO:0071482	cellular response to light stimulus	Rpgr	IMP	MGI:MGI:2386674	Mouse	PMID:10725384
Biological Process	GO:0060271	cilium assembly	RPGR	IMP		Human	PMID:21933838
Biological Process	GO:0060271	cilium assembly	rpgrb	IMP	ZFIN:ZDB-MRPHLNO-100326-1	Zfish	PMID:19815619
Biological Process	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	rpgrb	IMP	ZFIN:ZDB-MRPHLNO-100326-1	Zfish	PMID:19815619
Biological Process	GO:0042462	eye photoreceptor cell development	Rpgr	IMP	MGI:MGI:2386674	Mouse	PMID:12651948
Biological Process	GO:0042073	intraciliary transport	Rpgr	IMP		Mouse	MGI:MGI:3814789|PMID:18579752
Biological Process	GO:0007018	microtubule-based movement	rpgrb	IMP	ZFIN:ZDB-MRPHLNO-100413-2	Zfish	PMID:19955120
Biological Process	GO:0060041	retina development in camera-type eye	rpgrb	IMP	ZFIN:ZDB-MRPHLNO-100413-2	Zfish	PMID:19955120
Biological Process	GO:0010842	retina layer formation	rpgrb	IMP	ZFIN:ZDB-MRPHLNO-100413-2	Zfish	PMID:19955120
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	Rpgr	IMP	MGI:MGI:2386674	Mouse	PMID:10725384
Biological Process	GO:0046548	retinal rod cell development	rpgrb	IMP	ZFIN:ZDB-MRPHLNO-100326-1	Zfish	PMID:24043777
Biological Process	GO:0046548	retinal rod cell development	rpgrb	IGI	ZFIN:ZDB-MRPHLNO-100326-1,ZFIN:ZDB-MRPHLNO-131126-3	Zfish	PMID:24043777
Biological Process	GO:0007601	visual perception	RPGR	IMP		Human	PMID:9399904
Biological Process	GO:0007601	visual perception	Rpgr	IMP	MGI:MGI:2386674	Mouse	PMID:12651948

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern