Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Rph3a

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes RPH3A
- Mouse genes Rph3a
- Rat genes Rph3a
- Zfish genes rph3aa,rph3ab
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rph3a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Rph3a	IDA		Rat	PMID:17166855\|RGD:8554421
Molecular Function	GO:0005509	calcium ion binding	Rph3a	IDA		Rat	PMID:18945677\|RGD:2314874
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	Rph3a	IDA		Rat	PMID:17166855\|RGD:8554421
Molecular Function	GO:0070679	inositol 1,4,5 trisphosphate binding	Rph3a	IDA		Rat	PMID:18945677\|RGD:2314874
Molecular Function	GO:0042301	phosphate ion binding	Rph3a	IDA		Rat	PMID:11640918\|RGD:2314900
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Rph3a	IDA		Rat	PMID:18945677\|RGD:2314874
Molecular Function	GO:0005515	protein binding	RPH3A	IPI	UniProtKB:O14936	Human	PMID:11377421
Molecular Function	GO:0005515	protein binding	RPH3A	IPI	UniProtKB:P20336	Human	PMID:15207266
Molecular Function	GO:0005515	protein binding	RPH3A	IPI	UniProtKB:P37840	Human	PMID:15207266
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	UniProtKB:Q9ERI2	Mouse	MGI:MGI:2176311\|PMID:11773082
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	UniProtKB:P63011	Mouse	MGI:MGI:2176311\|PMID:11773082
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	UniProtKB:P55258\|UniProtKB:P63011\|UniProtKB:Q9ERI2	Mouse	MGI:MGI:2176311\|PMID:11773082
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	UniProtKB:P55258	Mouse	MGI:MGI:2176311\|PMID:11773082
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	UniProtKB:P55258\|UniProtKB:P63011\|UniProtKB:Q9ERI2	Mouse	MGI:MGI:4839453\|PMID:14722103
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	PR:Q8K386	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	RGD:11212	Rat	PMID:10025402\|RGD:2314908
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	UniProtKB:P63012	Rat	PMID:10025402\|RGD:2314908
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	RGD:3803	Rat	PMID:14960300\|RGD:2314877
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	UniProtKB:P60881	Rat	PMID:16763567\|RGD:8553578
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	UniProtKB:P63012	Rat	PMID:16763567\|RGD:8553578
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	UniProtKB:P31016	Rat	PMID:26679993\|RGD:11085451
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	UniProtKB:Q00959	Rat	PMID:26679993\|RGD:11085451
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	RGD:61992	Rat	PMID:7802677\|RGD:2314916
Molecular Function	GO:0005515	protein binding	Rph3a	IPI	UniProtKB:P63012	Rat	PMID:8617225\|RGD:14397552
Molecular Function	GO:0044877	protein-containing complex binding	Rph3a	IDA		Rat	PMID:14960300\|RGD:2314877
Molecular Function	GO:0008430	selenium binding	Rph3a	IDA		Rat	PMID:10025402\|RGD:2314908
Molecular Function	GO:0008270	zinc ion binding	Rph3a	IDA		Rat	PMID:10025402\|RGD:2314908
Cellular Component	GO:0098981	cholinergic synapse	Rph3a	IDA		Rat	PMID:8060298\|RGD:13702383
Cellular Component	GO:0005829	cytosol	Rph3a	IDA		Rat	PMID:18573236\|RGD:2314875
Cellular Component	GO:0043197	dendritic spine	Rph3a	IDA		Rat	PMID:26679993\|RGD:11085451
Cellular Component	GO:0019898	extrinsic component of membrane	Rph3a	IDA		Rat	PMID:7946335\|RGD:729719
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Rph3a	EXP		Rat	PMID:17110340\|RGD:12050113
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Rph3a	IDA		Rat	PMID:17110340\|RGD:12050113
Cellular Component	GO:0098850	extrinsic component of synaptic vesicle membrane	Rph3a	IDA		Rat	PMID:8060298\|RGD:13702383
Cellular Component	GO:0005794	Golgi apparatus	Rph3a	IDA		Rat	PMID:17395899\|RGD:2314876
Cellular Component	GO:0031594	neuromuscular junction	Rph3a	IDA		Rat	PMID:8060298\|RGD:13702383
Cellular Component	GO:0043005	neuron projection	Rph3a	IDA		Rat	PMID:14960300\|RGD:2314877
Cellular Component	GO:0045211	postsynaptic membrane	Rph3a	IDA		Rat	PMID:26679993\|RGD:11085451
Cellular Component	GO:0032991	protein-containing complex	Rph3a	IDA		Rat	PMID:14960300\|RGD:2314877
Cellular Component	GO:0030141	secretory granule	Rph3a	IDA		Rat	PMID:18573236\|RGD:2314875
Cellular Component	GO:0045202	synapse	Rph3a	IDA		Rat	PMID:11466417\|RGD:2314902
Cellular Component	GO:0008021	synaptic vesicle	Rph3a	IDA		Rat	PMID:11466417\|RGD:2314902
Cellular Component	GO:0008021	synaptic vesicle	Rph3a	IDA		Rat	PMID:14960300\|RGD:2314877
Cellular Component	GO:0008021	synaptic vesicle	Rph3a	IDA		Rat	PMID:8617225\|RGD:14397552
Cellular Component	GO:0030672	synaptic vesicle membrane	Rph3a	IDA		Rat	PMID:7946335\|RGD:729719
Biological Process	GO:0007420	brain development	Rph3a	IEP		Rat	PMID:11466417\|RGD:2314902
Biological Process	GO:0097061	dendritic spine organization	Rph3a	IMP		Rat	PMID:26679993\|RGD:11085451
Biological Process	GO:2000310	regulation of NMDA receptor activity	Rph3a	IMP		Rat	PMID:26679993\|RGD:11085451
Biological Process	GO:0061669	spontaneous neurotransmitter secretion	Rph3a	IGI	MGI:MGI:109446,MGI:MGI:1100497,MGI:MGI:1926250	Mouse	PMID:21521611
Biological Process	GO:0016082	synaptic vesicle priming	Rph3a	IDA		Mouse	PMID:16763567
Biological Process	GO:0016082	synaptic vesicle priming	Rph3a	IMP		Mouse	PMID:16763567

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.