Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RPH3AL
  • Mouse genes Rph3al
  • Rat genes Rph3al
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rph3al

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030274	LIM domain binding	Rph3al	IPI	RGD:1550839	Rat	PMID:9367993|RGD:633783
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:Q9UJV3-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:A0A024R8L2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:O00194	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:O43741	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:O75525	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:P61289	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:P61978-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:Q8N5M1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:Q9BWG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:Q9NX04	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:Q9UHP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:Q9UL41	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPH3AL	IPI	UniProtKB:X5D778	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	UniProtKB:P35276|UniProtKB:P63011|UniProtKB:Q9CZT8	Mouse	MGI:MGI:3653776|PMID:11598194
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	PR:Q9ERI2	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	PR:P35276	Mouse	PMID:15159548
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	PR:P63011	Mouse	PMID:15159548
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	PR:P35276	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	PR:Q9CZT8	Mouse	PMID:15159548
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	PR:P62823	Mouse	PMID:15159548
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	PR:P55258	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	MGI:MGI:1914545	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	PR:P63011	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	PR:Q9CZT8	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	PR:Q99P58	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rph3al	IPI	RGD:620114	Rat	PMID:17067543|RGD:1601610
Cellular Component	GO:0005737	cytoplasm	Rph3al	IDA		Rat	PMID:9367993|RGD:633783
Cellular Component	GO:0030141	secretory granule	Rph3al	IDA		Rat	PMID:17067543|RGD:1601610
Cellular Component	GO:0030667	secretory granule membrane	Rph3al	IDA		Rat	PMID:17067543|RGD:1601610
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Rph3al	IMP	MGI:MGI:3051976	Mouse	PMID:15159548
Biological Process	GO:0042593	glucose homeostasis	Rph3al	IDA		Mouse	MGI:MGI:3653776|PMID:11598194
Biological Process	GO:0042593	glucose homeostasis	Rph3al	IMP	MGI:MGI:3051976	Mouse	PMID:15159548
Biological Process	GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	Rph3al	IMP	MGI:MGI:3051976	Mouse	PMID:15159548
Biological Process	GO:0032024	positive regulation of insulin secretion	Rph3al	IDA		Mouse	MGI:MGI:3044444|PMID:15159548
Biological Process	GO:0050714	positive regulation of protein secretion	Rph3al	IMP		Rat	PMID:17067543|RGD:1601610
Biological Process	GO:0017158	regulation of calcium ion-dependent exocytosis	Rph3al	IMP	MGI:MGI:3051976	Mouse	PMID:15159548
Biological Process	GO:0009410	response to xenobiotic stimulus	Rph3al	IEP		Rat	PMID:17067543|RGD:1601610

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern