Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Rpl11

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes RPL11
- Mouse genes Rpl11
- Rat genes Rpl11
- Zfish genes rpl11
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rpl11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008097	5S rRNA binding	RPL11	IMP		Human	PMID:18560357
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	Rpl11	IPI	RGD:3369	Rat	PMID:16280383\|RGD:11035228
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:P29590-5	Human	PMID:15195100
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:P46777,UniProtKB:P62829,UniProtKB:Q00987	Human	PMID:15314173
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q00987	Human	PMID:17110929
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q00987	Human	PMID:17310983
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q00987	Human	PMID:17373842
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:P01106	Human	PMID:17599065
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q15843	Human	PMID:18274552
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:P46777,UniProtKB:Q00987	Human	PMID:18560357
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q92900	Human	PMID:19417104
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q00987	Human	PMID:19713960
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q15843	Human	PMID:19713960
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q15843	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q00987	Human	PMID:21399665
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q00987	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q00987	Human	PMID:23507139
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q8WXC6-2	Human	PMID:23776465
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q9NZM5	Human	PMID:24556985
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:P19712:PRO_0000038050	Human	PMID:24965446
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q13554	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:P08238	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	RPL11	IPI	UniProtKB:Q9NZM5	Human	PMID:27829214
Molecular Function	GO:0005515	protein binding	Rpl11	IPI	UniProtKB:P02340,UniProtKB:P23804	Mouse	MGI:MGI:5883206\|PMID:22262176
Molecular Function	GO:0005515	protein binding	Rpl11	IPI	UniProtKB:P23804\|UniProtKB:Q8BK35	Mouse	MGI:MGI:5897550\|PMID:21804542
Molecular Function	GO:0005515	protein binding	Rpl11	IPI	UniProtKB:P23804	Mouse	MGI:MGI:5437555\|PMID:22789538
Molecular Function	GO:0005515	protein binding	Rpl11	IPI	UniProtKB:P23804	Mouse	MGI:MGI:4830897\|PMID:20832751
Molecular Function	GO:0005515	protein binding	Rpl11	IPI	UniProtKB:P29590\|UniProtKB:Q00987	Mouse	MGI:MGI:4942242\|PMID:15195100
Molecular Function	GO:0005515	protein binding	Rpl11	IPI	UniProtKB:P23804	Mouse	MGI:MGI:3760347\|PMID:17936560
Molecular Function	GO:0003723	RNA binding	RPL11	HDA		Human	PMID:22681889
Molecular Function	GO:0003735	structural constituent of ribosome	RPL11	IMP		Human	PMID:18697920
Molecular Function	GO:0003735	structural constituent of ribosome	RPL11	IDA		Human	PMID:23636399
Molecular Function	GO:0003735	structural constituent of ribosome	RPL11	IDA		Human	PMID:32669547
Molecular Function	GO:0003735	structural constituent of ribosome	Rpl11	IDA		Mouse	MGI:MGI:7432473\|PMID:36517592
Molecular Function	GO:1990948	ubiquitin ligase inhibitor activity	RPL11	IMP		Human	PMID:18560357
Molecular Function	GO:0031625	ubiquitin protein ligase binding	RPL11	IPI	UniProtKB:Q00987	Human	PMID:18560357
Cellular Component	GO:0005737	cytoplasm	RPL11	IDA		Human	PMID:15314173
Cellular Component	GO:0005737	cytoplasm	RPL11	HDA		Human	PMID:16791210
Cellular Component	GO:0005737	cytoplasm	RPL11	IDA		Human	PMID:24120868
Cellular Component	GO:0005737	cytoplasm	Rpl11	IDA		Mouse	MGI:MGI:5897550\|PMID:21804542
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL11	IPI		Human	PMID:25901680
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL11	HDA		Human	PMID:12962325
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL11	IDA		Human	PMID:25957688
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL11	IDA		Human	PMID:32669547
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl11	IPI		Mouse	MGI:MGI:6810796\|PMID:25901680
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl11	IDA		Mouse	MGI:MGI:7432473\|PMID:36517592
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl11	IDA		Rat	PMID:3988767\|RGD:11035230
Cellular Component	GO:0022626	cytosolic ribosome	RPL11	IDA		Human	PMID:23636399
Cellular Component	GO:0022626	cytosolic ribosome	Rpl11	IDA		Rat	PMID:3733691\|RGD:11035229
Cellular Component	GO:0070062	extracellular exosome	RPL11	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	RPL11	HDA		Human	PMID:19946888
Cellular Component	GO:0005730	nucleolus	RPL11	IDA		Human	PMID:15195100
Cellular Component	GO:0005730	nucleolus	RPL11	HDA		Human	PMID:16791210
Cellular Component	GO:0005730	nucleolus	RPL11	IDA		Human	PMID:23776465
Cellular Component	GO:0005730	nucleolus	Rpl11	IDA		Mouse	MGI:MGI:4942242\|PMID:15195100
Cellular Component	GO:0005730	nucleolus	Rpl11	IDA		Mouse	MGI:MGI:5897550\|PMID:21804542
Cellular Component	GO:0005654	nucleoplasm	RPL11	IDA		Human	PMID:23776465
Cellular Component	GO:0005654	nucleoplasm	RPL11	IDA		Human	PMID:24120868
Cellular Component	GO:0042788	polysomal ribosome	RPL11	IDA		Human	PMID:25957688
Cellular Component	GO:0032991	protein-containing complex	RPL11	IDA		Human	PMID:15314173
Cellular Component	GO:0045202	synapse	Rpl11	EXP		Rat	PMID:15020595\|RGD:13702264
Cellular Component	GO:0045202	synapse	Rpl11	IDA		Rat	PMID:15020595\|RGD:13702264
Biological Process	GO:0006915	apoptotic process	rpl11	IMP	ZFIN:ZDB-MRPHLNO-070327-7	Zfish	PMID:19129914
Biological Process	GO:0006915	apoptotic process	rpl11	IMP	ZFIN:ZDB-MRPHLNO-070126-7,ZFIN:ZDB-MRPHLNO-070327-7	Zfish	PMID:19129914
Biological Process	GO:0043009	chordate embryonic development	rpl11	IMP	ZFIN:ZDB-MRPHLNO-070327-7	Zfish	PMID:17183665
Biological Process	GO:0002181	cytoplasmic translation	RPL11	IDA		Human	PMID:25957688
Biological Process	GO:0048821	erythrocyte development	rpl11	IGI	ZFIN:ZDB-GENE-990415-270	Zfish	PMID:26109203
Biological Process	GO:0048821	erythrocyte development	rpl11	IMP	ZFIN:ZDB-MRPHLNO-070327-7	Zfish	PMID:26109203
Biological Process	GO:0030218	erythrocyte differentiation	rpl11	IMP	ZFIN:ZDB-GENO-081229-22	Zfish	PMID:21114664
Biological Process	GO:0042593	glucose homeostasis	rpl11	IMP	ZFIN:ZDB-GENO-081229-22	Zfish	PMID:21114664
Biological Process	GO:0042541	hemoglobin biosynthetic process	rpl11	IMP	ZFIN:ZDB-GENO-140812-3	Zfish	PMID:25058426
Biological Process	GO:0030097	hemopoiesis	rpl11	IMP	ZFIN:ZDB-MRPHLNO-070327-7	Zfish	PMID:26484089
Biological Process	GO:0030097	hemopoiesis	rpl11	IMP	ZFIN:ZDB-MRPHLNO-070327-7	Zfish	PMID:24341334
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	Rpl11	IDA		Rat	PMID:16280383\|RGD:11035228
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	Rpl11	IMP		Mouse	MGI:MGI:5897550\|PMID:21804542
Biological Process	GO:2000435	negative regulation of protein neddylation	RPL11	IDA		Human	PMID:18560357
Biological Process	GO:1904667	negative regulation of ubiquitin protein ligase activity	RPL11	IMP		Human	PMID:18560357
Biological Process	GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	RPL11	IMP		Human	PMID:18560357
Biological Process	GO:0010628	positive regulation of gene expression	RPL11	IDA		Human	PMID:18560357
Biological Process	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Rpl11	IMP		Mouse	MGI:MGI:5883206\|PMID:22262176
Biological Process	GO:0032092	positive regulation of protein binding	RPL11	IMP		Human	PMID:18560357
Biological Process	GO:1901798	positive regulation of signal transduction by p53 class mediator	Rpl11	IMP		Mouse	MGI:MGI:5897550\|PMID:21804542
Biological Process	GO:0034504	protein localization to nucleus	Rpl11	IMP		Mouse	MGI:MGI:4942242\|PMID:15195100
Biological Process	GO:0050821	protein stabilization	RPL11	IMP		Human	PMID:18560357
Biological Process	GO:0006605	protein targeting	RPL11	IMP		Human	PMID:15195100
Biological Process	GO:0045088	regulation of innate immune response	rpl11	IMP	ZFIN:ZDB-GENO-081229-22	Zfish	PMID:29581525
Biological Process	GO:1901796	regulation of signal transduction by p53 class mediator	RPL11	IMP		Human	PMID:24120868
Biological Process	GO:0000027	ribosomal large subunit assembly	RPL11	IMP		Human	PMID:24120868
Biological Process	GO:0042273	ribosomal large subunit biogenesis	RPL11	IMP		Human	PMID:18697920
Biological Process	GO:0006364	rRNA processing	RPL11	IMP		Human	PMID:18697920

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.