Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RPL22
  • Mouse genes Rpl22
  • Rat genes Rpl22
  • Zfish genes rpl22
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rpl22

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008201	heparin binding	Rpl22	IDA		Mouse	PMID:8135813
Molecular Function	GO:0042802	identical protein binding	RPL22	IPI	UniProtKB:P35268	Human	PMID:32296183
Molecular Function	GO:0036002	pre-mRNA binding	rpl22	IGI	ZFIN:ZDB-GENE-060804-3	Zfish	PMID:28076796
Molecular Function	GO:0036002	pre-mRNA binding	rpl22	IPI	ZFIN:ZDB-GENE-990603-7	Zfish	PMID:28076796
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:P08392	Human	PMID:11145900
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:P17473	Human	PMID:11145900
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:Q8IWS0	Human	PMID:22720776
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:O00560	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:Q9H190	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:O75683	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:Q5HYN5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:Q8N7W2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:Q8TBK6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:Q92914	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:Q96CW1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:Q96MF2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:Q9H190	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:Q9NVV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:U3KQK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RPL22	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0003723	RNA binding	RPL22	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	RPL22	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	rpl22	IPI	ZFIN:ZDB-GENE-991119-8	Zfish	PMID:23449473
Molecular Function	GO:0003735	structural constituent of ribosome	RPL22	IDA		Human	PMID:23636399
Molecular Function	GO:0003735	structural constituent of ribosome	RPL22	IDA		Human	PMID:32669547
Molecular Function	GO:0003735	structural constituent of ribosome	Rpl22	IDA		Mouse	MGI:MGI:7432473|PMID:36517592
Cellular Component	GO:0005737	cytoplasm	RPL22	IDA		Human	PMID:8135813
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL22	HDA		Human	PMID:12962325
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL22	IDA		Human	PMID:32669547
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl22	IDA		Mouse	MGI:MGI:7432473|PMID:36517592
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl22	IDA		Rat	PMID:1002715|RGD:11036093
Cellular Component	GO:0022626	cytosolic ribosome	RPL22	IDA		Human	PMID:23636399
Cellular Component	GO:0070062	extracellular exosome	RPL22	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	RPL22	HDA		Human	PMID:21423176
Cellular Component	GO:0098978	glutamatergic synapse	Rpl22	IMP		Mouse	PMID:27321671
Cellular Component	GO:0098978	glutamatergic synapse	Rpl22	IPI		Mouse	PMID:27321671
Cellular Component	GO:0098978	glutamatergic synapse	Rpl22	IDA		Mouse	PMID:27321671
Cellular Component	GO:0005634	nucleus	RPL22	IDA		Human	PMID:22720776
Cellular Component	GO:0005634	nucleus	rpl22	IDA		Zfish	PMID:28076796
Cellular Component	GO:0098793	presynapse	Rpl22	IDA		Mouse	PMID:27321671
Cellular Component	GO:0098793	presynapse	Rpl22	IMP		Mouse	PMID:27321671
Cellular Component	GO:0032991	protein-containing complex	rpl22	IPI	ZFIN:ZDB-GENE-030912-14	Zfish	PMID:28076796
Cellular Component	GO:1990904	ribonucleoprotein complex	RPL22	IDA		Human	PMID:18809582
Cellular Component	GO:0005840	ribosome	Rpl22	IDA		Mouse	PMID:27321671
Cellular Component	GO:0005840	ribosome	Rpl22	IMP		Mouse	PMID:27321671
Cellular Component	GO:0005840	ribosome	Rpl22	IDA		Rat	PMID:8135813|RGD:11036074
Cellular Component	GO:0045202	synapse	Rpl22	IDA		Mouse	PMID:25211037
Biological Process	GO:0046632	alpha-beta T cell differentiation	Rpl22	IMP	MGI:MGI:3804429	Mouse	PMID:17555992
Biological Process	GO:0060028	convergent extension involved in axis elongation	rpl22	IMP		Zfish	PMID:28076796
Biological Process	GO:0060028	convergent extension involved in axis elongation	rpl22	IGI	ZFIN:ZDB-GENE-060804-3,ZFIN:ZDB-GENE-030912-14	Zfish	PMID:28076796
Biological Process	GO:0060028	convergent extension involved in axis elongation	rpl22	IMP	ZFIN:ZDB-MRPHLNO-180411-2	Zfish	PMID:28076796
Biological Process	GO:0060028	convergent extension involved in axis elongation	rpl22	IGI	ZFIN:ZDB-GENE-060804-3	Zfish	PMID:28076796
Biological Process	GO:1905744	regulation of mRNA cis splicing, via spliceosome	rpl22	IGI	ZFIN:ZDB-GENE-060804-3	Zfish	PMID:28076796
Biological Process	GO:0033077	T cell differentiation in thymus	rpl22	IMP	ZFIN:ZDB-MRPHLNO-130422-1	Zfish	PMID:23449473
Biological Process	GO:0140236	translation at presynapse	Rpl22	IDA		Mouse	PMID:27321671
Biological Process	GO:0140236	translation at presynapse	Rpl22	IPI		Mouse	PMID:27321671
Biological Process	GO:0140236	translation at presynapse	Rpl22	IMP		Mouse	PMID:27321671

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern