Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RPL4
  • Mouse genes Rpl4
  • Rat genes Rpl4
  • Zfish genes rpl4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rpl4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008097	5S rRNA binding	Rpl4	IDA		Rat	PMID:3301408|RGD:11036099
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:Q99558	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:Q8IWS0	Human	PMID:22720776
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:P42858	Human	PMID:23275563
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:O94876	Human	PMID:24454821
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:P19712:PRO_0000038050	Human	PMID:24965446
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:P60866	Human	PMID:25866880
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:P46779	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:P50914	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:Q02543	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:P46779	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:P50914	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:Q02543	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:Q99558	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RPL4	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Rpl4	IPI	PR:O89086	Mouse	PMID:15684048
Molecular Function	GO:0005515	protein binding	Rpl4	IPI	UniProtKB:Q925G0	Rat	PMID:15684048|RGD:8554266
Molecular Function	GO:0003723	RNA binding	RPL4	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	RPL4	HDA		Human	PMID:22681889
Molecular Function	GO:0003735	structural constituent of ribosome	RPL4	IDA		Human	PMID:23636399
Molecular Function	GO:0003735	structural constituent of ribosome	RPL4	IDA		Human	PMID:32669547
Molecular Function	GO:0003735	structural constituent of ribosome	Rpl4	IDA		Mouse	MGI:MGI:7432473|PMID:36517592
Cellular Component	GO:0031672	A band	Rpl4	IDA		Rat	PMID:2188648|RGD:11036104
Cellular Component	GO:0005737	cytoplasm	RPL4	HDA		Human	PMID:16791210
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL4	IPI		Human	PMID:25901680
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL4	HDA		Human	PMID:12962325
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL4	IDA		Human	PMID:32669547
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl4	IDA		Mouse	MGI:MGI:7432473|PMID:36517592
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl4	IPI		Mouse	MGI:MGI:6810796|PMID:25901680
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl4	IDA		Rat	PMID:3730400|RGD:11036081
Cellular Component	GO:0022626	cytosolic ribosome	RPL4	IDA		Human	PMID:23636399
Cellular Component	GO:0070062	extracellular exosome	RPL4	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	RPL4	HDA		Human	PMID:21423176
Cellular Component	GO:0015934	large ribosomal subunit	Rpl4	IDA		Rat	PMID:15684048|RGD:8554266
Cellular Component	GO:0016020	membrane	RPL4	HDA		Human	PMID:19946888
Cellular Component	GO:0005730	nucleolus	RPL4	HDA		Human	PMID:16791210
Cellular Component	GO:0005634	nucleus	RPL4	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	RPL4	IDA		Human	PMID:22720776
Cellular Component	GO:0014069	postsynaptic density	Rpl4	EXP		Rat	PMID:16507876|RGD:13702274
Cellular Component	GO:0014069	postsynaptic density	Rpl4	IDA		Rat	PMID:16507876|RGD:13702274
Cellular Component	GO:1990904	ribonucleoprotein complex	RPL4	IDA		Human	PMID:18809582
Cellular Component	GO:0005791	rough endoplasmic reticulum	RPL4	IDA		Human	PMID:24454821
Biological Process	GO:0007420	brain development	Rpl4	IEP		Rat	PMID:12168788|RGD:11039442
Biological Process	GO:0003360	brainstem development	Rpl4	IEP		Rat	PMID:12168788|RGD:11039442
Biological Process	GO:0030154	cell differentiation	Rpl4	IEP		Rat	PMID:10964612|RGD:11039443
Biological Process	GO:0071417	cellular response to organonitrogen compound	Rpl4	IEP		Rat	PMID:9813173|RGD:11039439
Biological Process	GO:0045773	positive regulation of axon extension	Rpl4	IMP		Rat	PMID:10964612|RGD:11039443
Biological Process	GO:0050772	positive regulation of axonogenesis	Rpl4	IMP		Rat	PMID:10964612|RGD:11039443

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern