Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RPL8
  • Mouse genes Rpl8
  • Rat genes Rpl8,Rpl8-ps7
  • Zfish genes rpl8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rpl8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990932	5.8S rRNA binding	Rpl8	IDA		Rat	PMID:468846|RGD:11036085
Molecular Function	GO:0005515	protein binding	RPL8	IPI	UniProtKB:Q99558	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	RPL8	IPI	UniProtKB:Q99558	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Rpl8	IPI	UniProtKB:P97784	Mouse	MGI:MGI:5009503|PMID:19129230
Molecular Function	GO:0003723	RNA binding	RPL8	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	RPL8	HDA		Human	PMID:22681889
Molecular Function	GO:0003735	structural constituent of ribosome	RPL8	IDA		Human	PMID:23636399
Molecular Function	GO:0003735	structural constituent of ribosome	RPL8	IDA		Human	PMID:32669547
Molecular Function	GO:0003735	structural constituent of ribosome	Rpl8	IDA		Mouse	MGI:MGI:7432473|PMID:36517592
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL8	IPI		Human	PMID:25901680
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL8	HDA		Human	PMID:12962325
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL8	IDA		Human	PMID:25957688
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	RPL8	IDA		Human	PMID:32669547
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl8	IPI		Mouse	MGI:MGI:6810796|PMID:25901680
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl8	IDA		Mouse	MGI:MGI:7432473|PMID:36517592
Cellular Component	GO:0022625	cytosolic large ribosomal subunit	Rpl8	IDA		Rat	PMID:863909|RGD:11036088
Cellular Component	GO:0022626	cytosolic ribosome	RPL8	IDA		Human	PMID:23636399
Cellular Component	GO:0005925	focal adhesion	RPL8	HDA		Human	PMID:21423176
Cellular Component	GO:0016020	membrane	RPL8	HDA		Human	PMID:19946888
Cellular Component	GO:0042788	polysomal ribosome	RPL8	IDA		Human	PMID:25957688
Cellular Component	GO:0098794	postsynapse	RPL8	EXP		Human	PMID:23071613
Cellular Component	GO:0098794	postsynapse	RPL8	IDA		Human	PMID:23071613
Cellular Component	GO:0014069	postsynaptic density	RPL8	EXP		Human	PMID:21170055
Cellular Component	GO:0014069	postsynaptic density	RPL8	IDA		Human	PMID:21170055
Cellular Component	GO:0045202	synapse	Rpl8	EXP		Mouse	PMID:16452087
Cellular Component	GO:0045202	synapse	Rpl8	IDA		Mouse	PMID:16452087
Cellular Component	GO:0045202	synapse	Rpl8	EXP		Mouse	PMID:23071613
Cellular Component	GO:0045202	synapse	Rpl8	IDA		Mouse	PMID:23071613
Cellular Component	GO:0045202	synapse	Rpl8	EXP		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Rpl8	IDA		Mouse	PMID:25211037
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Rpl8	IEP		Rat	PMID:11922865|RGD:11039448
Biological Process	GO:0002181	cytoplasmic translation	RPL8	IDA		Human	PMID:25957688

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern