Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RPS27L
  • Mouse genes Rps27l
  • Rat genes Rps27l
  • Zfish genes rps27l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rps27l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	RPS27L	IDA		Human	PMID:17057733
Molecular Function	GO:0005515	protein binding	RPS27L	IPI	UniProtKB:Q00987	Human	PMID:21170087
Molecular Function	GO:0003723	RNA binding	RPS27L	HDA		Human	PMID:22681889
Molecular Function	GO:0008494	translation activator activity	RPS27L	IDA		Human	PMID:18056458
Cellular Component	GO:0005634	nucleus	RPS27L	IDA		Human	PMID:18056458
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	RPS27L	IDA		Human	PMID:17057733
Biological Process	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	RPS27L	IDA		Human	PMID:18056458
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	RPS27L	IDA		Human	PMID:17057733
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	RPS27L	IDA		Human	PMID:18056458
Biological Process	GO:0031571	mitotic G1 DNA damage checkpoint signaling	RPS27L	IMP		Human	PMID:18056458
Biological Process	GO:0045727	positive regulation of translation	RPS27L	IDA		Human	PMID:18056458

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern