Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RPS6
  • Mouse genes Rps6-ps4
  • Rat genes Rps6
  • Zfish genes rps6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rps6-ps4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003729	mRNA binding	Rps6	IDA		Rat	PMID:7338522|RGD:11040966
Molecular Function	GO:0005515	protein binding	RPS6	IPI	UniProtKB:P08238	Human	PMID:16314389
Molecular Function	GO:0005515	protein binding	RPS6	IPI	UniProtKB:Q09161	Human	PMID:18423201
Molecular Function	GO:0005515	protein binding	RPS6	IPI	UniProtKB:Q92900	Human	PMID:19417104
Molecular Function	GO:0005515	protein binding	RPS6	IPI	UniProtKB:Q96RG2	Human	PMID:21418524
Molecular Function	GO:0005515	protein binding	RPS6	IPI	UniProtKB:O94876	Human	PMID:24454821
Molecular Function	GO:0005515	protein binding	RPS6	IPI	UniProtKB:P06748	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RPS6	IPI	UniProtKB:P06748	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	RPS6	IPI	UniProtKB:P06748	Human	PMID:30021884
Molecular Function	GO:0019901	protein kinase binding	RPS6	IPI	UniProtKB:Q96RG2	Human	PMID:21418524
Molecular Function	GO:0003723	RNA binding	RPS6	HDA		Human	PMID:22658674
Molecular Function	GO:0003735	structural constituent of ribosome	RPS6	HDA		Human	PMID:15883184
Molecular Function	GO:0003735	structural constituent of ribosome	RPS6	IMP		Human	PMID:18697920
Molecular Function	GO:0003735	structural constituent of ribosome	RPS6	IDA		Human	PMID:23636399
Molecular Function	GO:0003735	structural constituent of ribosome	RPS6	IDA		Human	PMID:34314702
Molecular Function	GO:0003735	structural constituent of ribosome	RPS6	IDA		Human	PMID:8706699
Molecular Function	GO:0003735	structural constituent of ribosome	Rps6	IMP		Rat	PMID:3378620|RGD:2299075
Cellular Component	GO:0044297	cell body	RPS6	IDA		Human	PMID:15121898
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	RPS6	IDA		Human	PMID:15121898
Cellular Component	GO:0005829	cytosol	RPS6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0022626	cytosolic ribosome	RPS6	IDA		Human	PMID:23636399
Cellular Component	GO:0022627	cytosolic small ribosomal subunit	RPS6	HDA		Human	PMID:15883184
Cellular Component	GO:0022627	cytosolic small ribosomal subunit	RPS6	IDA		Human	PMID:8706699
Cellular Component	GO:0022627	cytosolic small ribosomal subunit	Rps6	IDA		Rat	PMID:3378620|RGD:2299075
Cellular Component	GO:0022627	cytosolic small ribosomal subunit	Rps6	IDA		Rat	PMID:6196023|RGD:2299087
Cellular Component	GO:0022627	cytosolic small ribosomal subunit	Rps6	IDA		Rat	PMID:947902|RGD:2300010
Cellular Component	GO:0030425	dendrite	RPS6	IDA		Human	PMID:15121898
Cellular Component	GO:0005783	endoplasmic reticulum	RPS6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0098982	GABA-ergic synapse	Rps6	IDA		Rat	PMID:27764673|RGD:155230753
Cellular Component	GO:0016020	membrane	RPS6	HDA		Human	PMID:19946888
Cellular Component	GO:0005730	nucleolus	RPS6	IDA		Human	PMID:8590812
Cellular Component	GO:0005634	nucleus	RPS6	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	RPS6	IDA		Human	PMID:2334893
Cellular Component	GO:0098793	presynapse	Rps6	IDA		Rat	PMID:27764673|RGD:155230753
Cellular Component	GO:1990904	ribonucleoprotein complex	RPS6	IDA		Human	PMID:18809582
Cellular Component	GO:0005840	ribosome	Rps6	IDA		Rat	PMID:27764673|RGD:155230753
Cellular Component	GO:0015935	small ribosomal subunit	RPS6	IDA		Human	PMID:15590835
Biological Process	GO:0071361	cellular response to ethanol	Rps6	IDA		Rat	PMID:15530665|RGD:11041645
Biological Process	GO:0002181	cytoplasmic translation	RPS6	IDA		Human	PMID:34314702
Biological Process	GO:0002181	cytoplasmic translation	RPS6	IDA		Human	PMID:8706699
Biological Process	GO:1903347	negative regulation of bicellular tight junction assembly	Rps6	IDA		Rat	PMID:25217631|RGD:11041641
Biological Process	GO:0043065	positive regulation of apoptotic process	RPS6	IDA		Human	PMID:18362888
Biological Process	GO:0008284	positive regulation of cell population proliferation	RPS6	IMP		Human	PMID:17220279
Biological Process	GO:0032868	response to insulin	Rps6	IDA		Rat	PMID:17957382|RGD:11041640
Biological Process	GO:0000028	ribosomal small subunit assembly	Rps6	IMP		Rat	PMID:3378620|RGD:2299075
Biological Process	GO:0042274	ribosomal small subunit biogenesis	RPS6	IMP		Human	PMID:18697920
Biological Process	GO:0006364	rRNA processing	RPS6	IMP		Human	PMID:18697920
Biological Process	GO:0031929	TOR signaling	RPS6	IDA		Human	PMID:16428328

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern