Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RPS6KB2
  • Mouse genes Rps6kb2
  • Rat genes Rps6kb2
  • Zfish genes rps6kb1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rps6kb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Rps6kb2	IDA		Rat	PMID:11574531|RGD:1626103
Molecular Function	GO:0042277	peptide binding	Rps6kb2	IDA		Rat	PMID:11431469|RGD:1626102
Molecular Function	GO:0042277	peptide binding	Rps6kb2	IDA		Rat	PMID:11574531|RGD:1626103
Molecular Function	GO:0004672	protein kinase activity	Rps6kb2	IDA		Mouse	PMID:15249583
Molecular Function	GO:0004672	protein kinase activity	Rps6kb2	IDA		Rat	PMID:11431469|RGD:1626102
Molecular Function	GO:0004672	protein kinase activity	Rps6kb2	IDA		Rat	PMID:11574531|RGD:1626103
Molecular Function	GO:0004711	ribosomal protein S6 kinase activity	Rps6kb2	IMP		Rat	PMID:11574531|RGD:1626103
Biological Process	GO:0045948	positive regulation of translational initiation	RPS6KB2	IMP		Human	PMID:16763566
Biological Process	GO:0043491	protein kinase B signaling	Rps6kb2	IGI	MGI:MGI:99454	Mouse	PMID:15249583
Biological Process	GO:0043491	protein kinase B signaling	Rps6kb2	IGI	MGI:MGI:1270849	Mouse	PMID:15249583
Biological Process	GO:0043491	protein kinase B signaling	Rps6kb2	IGI	MGI:MGI:102548	Mouse	PMID:15249583
Biological Process	GO:0043491	protein kinase B signaling	Rps6kb2	IGI	MGI:MGI:87986	Mouse	PMID:15249583
Biological Process	GO:0006468	protein phosphorylation	Rps6kb2	IDA		Mouse	PMID:15249583
Biological Process	GO:0006468	protein phosphorylation	Rps6kb2	IDA		Rat	PMID:11431469|RGD:1626102
Biological Process	GO:0006468	protein phosphorylation	Rps6kb2	IDA		Rat	PMID:11574531|RGD:1626103
Biological Process	GO:0031929	TOR signaling	RPS6KB2	IMP		Human	PMID:29750193

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern