Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RRN3,RRN3P1,RRN3P2
  • Mouse genes Rrn3
  • Rat genes Rrn3
  • Zfish genes rrn3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rrn3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070063	RNA polymerase binding	Rrn3	IDA		Mouse	PMID:8413268
Molecular Function	GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	RRN3	IDA		Human	PMID:22368283
Cellular Component	GO:0005730	nucleolus	RRN3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	RRN3	IDA		Human	PMID:28334682
Biological Process	GO:0007028	cytoplasm organization	Rrn3	IMP	MGI:MGI:3584037	Mouse	PMID:15989966
Biological Process	GO:0006352	DNA-templated transcription initiation	Rrn3	IDA		Mouse	PMID:8413268
Biological Process	GO:0048144	fibroblast proliferation	Rrn3	IMP	MGI:MGI:3584037	Mouse	PMID:15989966
Biological Process	GO:0048872	homeostasis of number of cells	Rrn3	IMP	MGI:MGI:3584037	Mouse	PMID:15989966
Biological Process	GO:0001701	in utero embryonic development	Rrn3	IMP	MGI:MGI:3584037	Mouse	PMID:15989966
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	Rrn3	IMP	MGI:MGI:3584037	Mouse	PMID:15989966
Biological Process	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Rrn3	IMP	MGI:MGI:3584037	Mouse	PMID:15989966
Biological Process	GO:0007000	nucleolus organization	Rrn3	IMP	MGI:MGI:3584037	Mouse	PMID:15989966
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Rrn3	IDA		Mouse	PMID:8413268
Biological Process	GO:0010976	positive regulation of neuron projection development	Rrn3	IMP		Rat	PMID:21098478|RGD:9587429
Biological Process	GO:2000142	regulation of DNA-templated transcription initiation	Rrn3	IDA		Mouse	PMID:8413268
Biological Process	GO:0042254	ribosome biogenesis	Rrn3	IMP	MGI:MGI:3584037	Mouse	PMID:15989966
Biological Process	GO:0006361	transcription initiation at RNA polymerase I promoter	Rrn3	IMP	MGI:MGI:3584037	Mouse	PMID:15989966

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern