Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RRP8
  • Mouse genes Rrp8
  • Rat genes Rrp8
  • Zfish genes rrp8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rrp8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035064	methylated histone binding	RRP8	IDA		Human	PMID:18485871
Molecular Function	GO:0005515	protein binding	RRP8	IPI	UniProtKB:O43463	Human	PMID:18485871
Molecular Function	GO:0005515	protein binding	RRP8	IPI	UniProtKB:Q96EB6	Human	PMID:18485871
Molecular Function	GO:0005515	protein binding	RRP8	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RRP8	IPI	UniProtKB:Q92997	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RRP8	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0003723	RNA binding	RRP8	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	RRP8	HDA		Human	PMID:22681889
Cellular Component	GO:0005677	chromatin silencing complex	RRP8	IDA		Human	PMID:18485871
Cellular Component	GO:0005829	cytosol	RRP8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0061773	eNoSc complex	RRP8	IPI		Human	PMID:18485871
Cellular Component	GO:0005730	nucleolus	RRP8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	RRP8	IDA		Human	PMID:18485871
Cellular Component	GO:0005654	nucleoplasm	RRP8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	RRP8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0033553	rDNA heterochromatin	RRP8	IDA		Human	PMID:18485871
Biological Process	GO:0042149	cellular response to glucose starvation	RRP8	IMP		Human	PMID:18485871
Biological Process	GO:0042149	cellular response to glucose starvation	RRP8	IMP		Human	PMID:21471221
Biological Process	GO:0097009	energy homeostasis	RRP8	IMP		Human	PMID:18485871
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	RRP8	IMP		Human	PMID:21471221
Biological Process	GO:0045786	negative regulation of cell cycle	RRP8	IMP		Human	PMID:18485871
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	RRP8	IMP		Human	PMID:18485871
Biological Process	GO:0031065	positive regulation of histone deacetylation	RRP8	IMP		Human	PMID:18485871
Biological Process	GO:0031062	positive regulation of histone methylation	RRP8	IMP		Human	PMID:18485871
Biological Process	GO:0000183	rDNA heterochromatin formation	RRP8	IDA		Human	PMID:18485871
Biological Process	GO:0000183	rDNA heterochromatin formation	RRP8	IMP		Human	PMID:18485871
Biological Process	GO:1903450	regulation of G1 to G0 transition	RRP8	IMP		Human	PMID:21471221
Biological Process	GO:0046015	regulation of transcription by glucose	RRP8	IMP		Human	PMID:18485871
Biological Process	GO:0046015	regulation of transcription by glucose	RRP8	IMP		Human	PMID:21471221

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern