Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RSC1A1
  • Mouse genes Rsc1a1
  • Rat genes Ddi2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rsc1a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RSC1A1	IPI	UniProtKB:P54727	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rsc1a1	IPI	PR:Q3U5F4	Mouse	PMID:16024787
Molecular Function	GO:0019871	sodium channel inhibitor activity	RSC1A1	IDA		Human	PMID:8836035
Cellular Component	GO:0005903	brush border	Rsc1a1	IDA		Mouse	PMID:15601832
Cellular Component	GO:0030054	cell junction	RSC1A1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Rsc1a1	IDA		Mouse	PMID:15601832
Cellular Component	GO:0005654	nucleoplasm	RSC1A1	IDA		Human	GO_REF:0000052
Biological Process	GO:0050892	intestinal absorption	Rsc1a1	IMP	MGI:MGI:3526519	Mouse	PMID:15601832
Biological Process	GO:0010829	negative regulation of glucose transmembrane transport	RSC1A1	IDA		Human	PMID:8836035
Biological Process	GO:0042997	negative regulation of Golgi to plasma membrane protein transport	RSC1A1	IDA		Human	PMID:22492015
Biological Process	GO:0032243	negative regulation of nucleoside transport	RSC1A1	IDA		Human	PMID:22492015
Biological Process	GO:0032243	negative regulation of nucleoside transport	Rsc1a1	IMP		Mouse	MGI:MGI:6436961|PMID:22492015
Biological Process	GO:1903077	negative regulation of protein localization to plasma membrane	Rsc1a1	IMP		Mouse	MGI:MGI:6436961|PMID:22492015
Biological Process	GO:0051051	negative regulation of transport	RSC1A1	IDA		Human	PMID:2675563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern