Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RSPO4
  • Mouse genes Rspo4
  • Rat genes Rspo4
  • Zfish genes rspo4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rspo4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:A0A024R8A9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:O75716	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:P45984	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:Q13064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:Q15935	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:Q2WGJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:Q6P158	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:Q8WWB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:Q96NT3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:Q9P2W3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:Q9Y3S2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:Q9Y4H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RSPO4	IPI	UniProtKB:X5D778	Human	PMID:32296183
Biological Process	GO:0035878	nail development	RSPO4	IMP		Human	PMID:17805348
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	RSPO4	IDA		Human	PMID:29769720

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern