Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RTKN
  • Mouse genes Rtkn
  • Rat genes Rtkn
  • Zfish genes rtkna,rtknb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rtkn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005095	GTPase inhibitor activity	RTKN	IDA		Human	PMID:10940294
Molecular Function	GO:0005095	GTPase inhibitor activity	Rtkn	IDA		Mouse	MGI:MGI:80870|PMID:8662891
Molecular Function	GO:0005515	protein binding	RTKN	IPI	UniProtKB:O14907	Human	PMID:10940294
Molecular Function	GO:0005515	protein binding	RTKN	IPI	UniProtKB:P61586	Human	PMID:12879077
Molecular Function	GO:0005515	protein binding	RTKN	IPI	UniProtKB:Q9UHD8	Human	PMID:16007136
Molecular Function	GO:0005515	protein binding	RTKN	IPI	UniProtKB:P61586	Human	PMID:18256687
Molecular Function	GO:0005515	protein binding	RTKN	IPI	UniProtKB:Q9QUI0	Human	PMID:18854161
Molecular Function	GO:0005515	protein binding	RTKN	IPI	UniProtKB:O60504	Human	PMID:19294487
Molecular Function	GO:0005515	protein binding	RTKN	IPI	UniProtKB:O60504-2	Human	PMID:19294487
Molecular Function	GO:0005515	protein binding	RTKN	IPI	UniProtKB:P61586	Human	PMID:19944695
Molecular Function	GO:0005515	protein binding	RTKN	IPI	UniProtKB:P61586	Human	PMID:22621765
Molecular Function	GO:0005515	protein binding	RTKN	IPI	UniProtKB:P61586	Human	PMID:22705156
Molecular Function	GO:0005515	protein binding	RTKN	IPI	UniProtKB:Q9QUI0	Human	PMID:24525234
Molecular Function	GO:0005515	protein binding	RTKN	IPI	UniProtKB:P61586	Human	PMID:25150978
Molecular Function	GO:0005515	protein binding	Rtkn	IPI	UniProtKB:P61586|UniProtKB:Q9QUI0	Mouse	MGI:MGI:4442283|PMID:20348415
Molecular Function	GO:0005515	protein binding	Rtkn	IPI	UniProtKB:P61586|UniProtKB:Q9QUI0	Mouse	MGI:MGI:4881358|PMID:21029865
Molecular Function	GO:0005515	protein binding	Rtkn	IPI	UniProtKB:P61586	Mouse	MGI:MGI:5437404|PMID:22404908
Molecular Function	GO:0005515	protein binding	Rtkn	IPI	UniProtKB:Q9QUI0	Mouse	MGI:MGI:3789432|PMID:18448676
Molecular Function	GO:0005515	protein binding	Rtkn	IPI	UniProtKB:P61586	Mouse	MGI:MGI:5508568|PMID:20300064
Molecular Function	GO:0031267	small GTPase binding	RTKN	IDA		Human	PMID:10940294
Molecular Function	GO:0031267	small GTPase binding	Rtkn	IDA		Mouse	MGI:MGI:80870|PMID:8662891
Molecular Function	GO:0031267	small GTPase binding	Rtkn	IDA		Mouse	PMID:15996550
Biological Process	GO:0042981	regulation of apoptotic process	RTKN	IDA		Human	PMID:15480428
Biological Process	GO:0007266	Rho protein signal transduction	RTKN	IDA		Human	PMID:15480428
Biological Process	GO:0007165	signal transduction	RTKN	IDA		Human	PMID:10940294

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern