Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RTN4RL1
  • Mouse genes Rtn4rl1
  • Rat genes Rtn4rl1
  • Zfish genes rtn4rl1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rtn4rl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035374	chondroitin sulfate binding	Rtn4rl1	IDA		Mouse	MGI:MGI:5461303|PMID:22406547
Molecular Function	GO:0008201	heparin binding	Rtn4rl1	IMP		Mouse	MGI:MGI:5461303|PMID:22406547
Molecular Function	GO:0005515	protein binding	RTN4RL1	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RTN4RL1	IPI	UniProtKB:P60410	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RTN4RL1	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RTN4RL1	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RTN4RL1	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	rtn4rl1b	IPI	UniProtKB:A8BBG3	Zfish	PMID:19765300
Molecular Function	GO:0038023	signaling receptor activity	RTN4RL1	IDA		Human	PMID:12694398
Cellular Component	GO:0009986	cell surface	RTN4RL1	IDA		Human	PMID:20463223
Cellular Component	GO:0009986	cell surface	Rtn4rl1	IDA		Rat	PMID:15673660|RGD:12790657
Cellular Component	GO:0009897	external side of plasma membrane	Rtn4rl1	IDA		Rat	PMID:12694398|RGD:1299553
Cellular Component	GO:0070062	extracellular exosome	RTN4RL1	HDA		Human	PMID:23533145
Cellular Component	GO:0045121	membrane raft	Rtn4rl1	IDA		Rat	PMID:12694398|RGD:1299553
Cellular Component	GO:0005886	plasma membrane	RTN4RL1	IDA		Human	PMID:12694398
Biological Process	GO:0022038	corpus callosum development	Rtn4rl1	IMP		Mouse	MGI:MGI:5824191|PMID:27339102
Biological Process	GO:0048681	negative regulation of axon regeneration	Rtn4rl1	IMP		Mouse	MGI:MGI:5461303|PMID:22406547
Biological Process	GO:0010977	negative regulation of neuron projection development	Rtn4rl1	IMP		Mouse	MGI:MGI:5461303|PMID:22406547

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern