Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RTRAF
  • Mouse genes Rtraf
  • Rat genes Rtraf
  • Zfish genes rtraf
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rtraf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	RTRAF	IPI	UniProtKB:Q9Y224	Human	PMID:15147888
Molecular Function	GO:0042802	identical protein binding	RTRAF	IPI	UniProtKB:Q9Y224	Human	PMID:24608264
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:P31343	Human	PMID:11507205
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q8N4C6	Human	PMID:15147888
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q67020	Human	PMID:21994455
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q52LJ0	Human	PMID:24608264
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q8NCA5	Human	PMID:24608264
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q92499	Human	PMID:24608264
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q9Y3I0	Human	PMID:24608264
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q8NCA5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q8NCA5	Human	PMID:28040436
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q52LJ0	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q92499	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q9Y3I0	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q8NCA5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RTRAF	IPI	UniProtKB:Q9UIG4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rtraf	IPI	RGD:71058	Rat	PMID:16518874|RGD:10054427
Molecular Function	GO:0003723	RNA binding	RTRAF	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	RTRAF	IDA		Human	PMID:24608264
Molecular Function	GO:0000993	RNA polymerase II complex binding	RTRAF	IDA		Human	PMID:16950395
Cellular Component	GO:0005813	centrosome	RTRAF	IDA		Human	PMID:15147888
Cellular Component	GO:0005737	cytoplasm	RTRAF	IDA		Human	PMID:24608264
Cellular Component	GO:0072686	mitotic spindle	RTRAF	IDA		Human	PMID:15147888
Cellular Component	GO:0005654	nucleoplasm	RTRAF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RTRAF	IDA		Human	PMID:15147888
Cellular Component	GO:0005634	nucleus	RTRAF	IDA		Human	PMID:24608264
Cellular Component	GO:0048471	perinuclear region of cytoplasm	RTRAF	IDA		Human	PMID:15147888
Cellular Component	GO:0072669	tRNA-splicing ligase complex	RTRAF	IDA		Human	PMID:21311021
Cellular Component	GO:0072669	tRNA-splicing ligase complex	RTRAF	IDA		Human	PMID:24870230
Biological Process	GO:0006469	negative regulation of protein kinase activity	RTRAF	IMP		Human	PMID:15147888
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	RTRAF	IMP		Human	PMID:16950395
Biological Process	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	RTRAF	IMP		Human	PMID:24870230

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern