Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RUVBL1
  • Mouse genes Ruvbl1
  • Rat genes Ruvbl1,Ruvbl1-ps1
  • Zfish genes ruvbl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ruvbl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043138	3'-5' DNA helicase activity	Ruvbl1	IDA		Rat	PMID:10336418|RGD:729809
Molecular Function	GO:0043531	ADP binding	Ruvbl1	IDA		Mouse	MGI:MGI:5700302|PMID:17636026
Molecular Function	GO:0005524	ATP binding	Ruvbl1	IDA		Mouse	MGI:MGI:5700302|PMID:17636026
Molecular Function	GO:0016887	ATP hydrolysis activity	RUVBL1	IDA		Human	PMID:10966108
Molecular Function	GO:0016887	ATP hydrolysis activity	RUVBL1	IMP		Human	PMID:33205750
Molecular Function	GO:0016887	ATP hydrolysis activity	RUVBL1	IDA		Human	PMID:33367824
Molecular Function	GO:0051117	ATPase binding	Ruvbl1	IPI	UniProtKB:Q9WTM5	Mouse	MGI:MGI:5700302|PMID:17636026
Molecular Function	GO:0045296	cadherin binding	RUVBL1	HDA		Human	PMID:25468996
Molecular Function	GO:0003678	DNA helicase activity	RUVBL1	IDA		Human	PMID:9843967
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q92993	Human	PMID:10966108
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:10966108
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:11080158
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q15906	Human	PMID:15647280
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q92993	Human	PMID:15647280
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q15906	Human	PMID:16230350
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q92993	Human	PMID:16230350
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:16230350
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y2X3	Human	PMID:17636026
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:G3I183	Human	PMID:17761535
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:O75665	Human	PMID:17761535
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:P25490	Human	PMID:18026119
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:P35222	Human	PMID:18087039
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:P63279	Human	PMID:18087039
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q92993	Human	PMID:18087039
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:18087039
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:O14746	Human	PMID:18358808
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:O60832	Human	PMID:18358808
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:18358808
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:O60832	Human	PMID:19179534
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:P38935	Human	PMID:19299493
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:20371770
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9H6T3,UniProtKB:Q9NWS0,UniProtKB:Q9UBK9,UniProtKB:Q9Y230,UniProtKB:Q9Y4R8	Human	PMID:20864032
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q70CQ1	Human	PMID:23824326
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:P04637	Human	PMID:25857266
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:O95905	Human	PMID:26711270
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:P25490	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:O60832	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:P25490	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q15906	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9UHR6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:29323271
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:O15259	Human	PMID:29959317
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:O75161	Human	PMID:29959317
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q15051	Human	PMID:29959317
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q7Z494	Human	PMID:29959317
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y283	Human	PMID:29959317
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9UHR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q14147	Human	PMID:33205750
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q96Q15	Human	PMID:33205750
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q9Y230	Human	PMID:33205750
Molecular Function	GO:0005515	protein binding	RUVBL1	IPI	UniProtKB:Q8N5I9,UniProtKB:Q9Y230,UniProtKB:Q9Y2X3	Human	PMID:33367824
Molecular Function	GO:0005515	protein binding	Ruvbl1	IPI	UniProtKB:Q9WTM5	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0005515	protein binding	Ruvbl1	IPI	UniProtKB:Q9NWS0|UniProtKB:Q9UHK0	Mouse	MGI:MGI:5705193|PMID:26496610
Molecular Function	GO:0005515	protein binding	Ruvbl1	IPI	UniProtKB:Q9NWS0|UniProtKB:Q9UHK0|UniProtKB:Q9WTM5	Mouse	MGI:MGI:5700302|PMID:17636026
Molecular Function	GO:0005515	protein binding	Ruvbl1	IPI	UniProtKB:P55769|UniProtKB:Q9NWK9|UniProtKB:Q9NWS0	Mouse	MGI:MGI:5700302|PMID:17636026
Molecular Function	GO:0005515	protein binding	Ruvbl1	IPI	UniProtKB:Q9WTM5	Mouse	MGI:MGI:6198825|PMID:29959317
Molecular Function	GO:0005515	protein binding	Ruvbl1	IPI	UniProtKB:P22087|UniProtKB:Q9UHK0	Mouse	MGI:MGI:5700302|PMID:17636026
Molecular Function	GO:0017025	TBP-class protein binding	RUVBL1	IDA		Human	PMID:11080158
Molecular Function	GO:0001094	TFIID-class transcription factor complex binding	Ruvbl1	IPI	UniProtKB:Q16594	Mouse	MGI:MGI:5700302|PMID:17636026
Molecular Function	GO:0003713	transcription coactivator activity	RUVBL1	IDA		Human	PMID:11080158
Cellular Component	GO:0005829	cytosol	RUVBL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	ruvbl1	IDA		Zfish	PMID:29113992
Cellular Component	GO:0070062	extracellular exosome	RUVBL1	HDA		Human	PMID:20458337
Cellular Component	GO:0031011	Ino80 complex	RUVBL1	IDA		Human	PMID:21303910
Cellular Component	GO:0031011	Ino80 complex	RUVBL1	IDA		Human	PMID:18026119
Cellular Component	GO:0071339	MLL1 complex	RUVBL1	IDA		Human	PMID:15960975
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	RUVBL1	IDA		Human	PMID:27153538
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	RUVBL1	IDA		Human	PMID:10966108
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	RUVBL1	IDA		Human	PMID:14966270
Cellular Component	GO:0016363	nuclear matrix	Ruvbl1	IDA		Rat	PMID:10050036|RGD:68302
Cellular Component	GO:0005654	nucleoplasm	RUVBL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000786	nucleosome	RUVBL1	IDA		Human	PMID:27153538
Cellular Component	GO:0005634	nucleus	RUVBL1	IDA		Human	PMID:18026119
Cellular Component	GO:0005634	nucleus	RUVBL1	IDA		Human	PMID:9843967
Cellular Component	GO:0005634	nucleus	Ruvbl1	IDA		Rat	PMID:10565543|RGD:2316867
Cellular Component	GO:0101031	protein folding chaperone complex	RUVBL1	IPI		Human	PMID:29844425
Cellular Component	GO:0032991	protein-containing complex	Ruvbl1	IDA		Rat	PMID:10565543|RGD:2316867
Cellular Component	GO:0097255	R2TP complex	RUVBL1	IPI		Human	PMID:29662061
Cellular Component	GO:0097255	R2TP complex	RUVBL1	IDA		Human	PMID:26711270
Cellular Component	GO:0097255	R2TP complex	RUVBL1	IDA		Human	PMID:33367824
Cellular Component	GO:1990904	ribonucleoprotein complex	Ruvbl1	IDA		Mouse	PMID:19299493
Cellular Component	GO:1990062	RPAP3/R2TP/prefoldin-like complex	RUVBL1	IPI		Human	PMID:31738558
Cellular Component	GO:0000812	Swr1 complex	RUVBL1	IDA		Human	PMID:24463511
Biological Process	GO:0070286	axonemal dynein complex assembly	ruvbl1	IMP	ZFIN:ZDB-GENO-180607-6	Zfish	PMID:29113992
Biological Process	GO:0006338	chromatin remodeling	RUVBL1	IDA		Human	PMID:21303910
Biological Process	GO:0003351	epithelial cilium movement involved in extracellular fluid movement	ruvbl1	IMP	ZFIN:ZDB-GENO-180607-6	Zfish	PMID:29113992
Biological Process	GO:0007507	heart development	ruvbl1	IMP	ZFIN:ZDB-MRPHLNO-110519-3	Zfish	PMID:12464178
Biological Process	GO:0007507	heart development	ruvbl1	IMP	ZFIN:ZDB-MRPHLNO-110519-4	Zfish	PMID:12464178
Biological Process	GO:0043968	histone H2A acetylation	RUVBL1	IDA		Human	PMID:27153538
Biological Process	GO:0043967	histone H4 acetylation	RUVBL1	IDA		Human	PMID:27153538
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	RUVBL1	IDA		Human	PMID:11080158
Biological Process	GO:0045739	positive regulation of DNA repair	Ruvbl1	IDA		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	RUVBL1	IMP		Human	PMID:27641337
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	RUVBL1	IDA		Human	PMID:27153538
Biological Process	GO:0010756	positive regulation of plasminogen activation	Ruvbl1	IDA		Rat	PMID:11027681|RGD:67924
Biological Process	GO:1904874	positive regulation of telomerase RNA localization to Cajal body	RUVBL1	HMP		Human	PMID:25467444
Biological Process	GO:1904507	positive regulation of telomere maintenance in response to DNA damage	Ruvbl1	IMP		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0051726	regulation of cell cycle	RUVBL1	IMP		Human	PMID:26340092
Biological Process	GO:0051726	regulation of cell cycle	RUVBL1	IMP		Human	PMID:27153538
Biological Process	GO:0033044	regulation of chromosome organization	RUVBL1	IMP		Human	PMID:26340092
Biological Process	GO:0006282	regulation of DNA repair	Ruvbl1	IDA		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0006275	regulation of DNA replication	RUVBL1	IMP		Human	PMID:25016522
Biological Process	GO:0060382	regulation of DNA strand elongation	RUVBL1	IMP		Human	PMID:25016522
Biological Process	GO:0045995	regulation of embryonic development	Ruvbl1	IMP		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:2000269	regulation of fibroblast apoptotic process	Ruvbl1	IMP		Rat	PMID:12185582|RGD:9588231
Biological Process	GO:0060420	regulation of heart growth	ruvbl1	IMP	ZFIN:ZDB-MRPHLNO-110519-4	Zfish	PMID:12464178
Biological Process	GO:0060420	regulation of heart growth	ruvbl1	IMP	ZFIN:ZDB-MRPHLNO-110519-3	Zfish	PMID:12464178
Biological Process	GO:0000723	telomere maintenance	Ruvbl1	IMP		Mouse	MGI:MGI:5638510|PMID:23979016

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern