Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RXRB
  • Mouse genes Rxrb
  • Rat genes Rxrb
  • Zfish genes rxrba,rxrbb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rxrb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031490	chromatin DNA binding	Rxrb	IDA		Mouse	PMID:29431742
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	RXRB	IDA		Human	PMID:12767074
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	rxrba	IDA		Zfish	PMID:7565671
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	rxrbb	IDA		Zfish	PMID:7565671
Molecular Function	GO:0004879	nuclear receptor activity	RXRB	IDA		Human	PMID:1662118
Molecular Function	GO:0004879	nuclear receptor activity	RXRB	IDA		Human	PMID:7990953
Molecular Function	GO:0004879	nuclear receptor activity	Rxrb	IDA		Rat	PMID:1662118|RGD:729677
Molecular Function	GO:0030374	nuclear receptor coactivator activity	Rxrb	IDA		Rat	PMID:1662118|RGD:729677
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	Rxrb	IDA		Rat	PMID:1662118|RGD:729677
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	Rxrb	IDA		Rat	PMID:1662118|RGD:729677
Molecular Function	GO:0042809	nuclear vitamin D receptor binding	Rxrb	IDA		Rat	PMID:1662118|RGD:729677
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10276	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:Q00975	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P04150	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10276	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P37231	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10276	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10276	Human	PMID:25303530
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10826-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:Q13133	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P37231	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10276	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10276-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10826-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:Q13133-3	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:Q96RI1-1	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10276-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P13631	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:Q96RI1-1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10276	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10276	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:F1D8P7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10276	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P10826-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:P13631	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:Q13133-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:Q6IQ16	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:Q96RI1-1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:Q9HB07	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RXRB	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rxrb	IPI	UniProtKB:Q8CBD1	Mouse	MGI:MGI:3687657|PMID:10531331
Molecular Function	GO:0044877	protein-containing complex binding	Rxrb	IDA		Rat	PMID:1662118|RGD:729677
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	RXRB	IDA		Human	PMID:12767074
Molecular Function	GO:0043565	sequence-specific DNA binding	Rxrb	IGI	MGI:MGI:97857	Mouse	PMID:7823919
Molecular Function	GO:0043565	sequence-specific DNA binding	Rxrb	IGI	MGI:MGI:97856	Mouse	PMID:7823919
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	RXRB	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Rxrb	IDA		Mouse	MGI:MGI:4820711|PMID:18922886
Cellular Component	GO:0005654	nucleoplasm	RXRB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RXRB	IDA		Human	PMID:7990953
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	RXRB	IPI		Human	PMID:25416956
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	RXRB	IPI		Human	PMID:27011007
Biological Process	GO:0060038	cardiac muscle cell proliferation	Rxrb	IGI	MGI:MGI:98214	Mouse	PMID:9428411
Biological Process	GO:0071300	cellular response to retinoic acid	Rxrb	IDA		Mouse	MGI:MGI:4820711|PMID:18922886
Biological Process	GO:0006354	DNA-templated transcription elongation	rxrbb	IDA		Zfish	PMID:7565671|ZFIN:ZDB-PUB-961014-511
Biological Process	GO:0001701	in utero embryonic development	Rxrb	IGI	MGI:MGI:98214	Mouse	PMID:9892670
Biological Process	GO:0001893	maternal placenta development	Rxrb	IGI	MGI:MGI:98214	Mouse	PMID:9892670
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	rxrbb	IDA		Zfish	PMID:7565671|ZFIN:ZDB-PUB-961014-511
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	rxrba	IDA		Zfish	PMID:7565671
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	RXRB	IDA		Human	PMID:1662118
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	RXRB	IDA		Human	PMID:12767074
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Rxrb	IGI	MGI:MGI:97857	Mouse	PMID:7823919
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Rxrb	IGI	MGI:MGI:97856	Mouse	PMID:7823919
Biological Process	GO:0006355	regulation of DNA-templated transcription	rxrba	IDA		Zfish	PMID:7565671|ZFIN:ZDB-PUB-961014-511
Biological Process	GO:0031641	regulation of myelination	Rxrb	IDA		Rat	PMID:20648638|RGD:6771320
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	rxrbb	IDA		Zfish	PMID:7565671|ZFIN:ZDB-PUB-961014-511
Biological Process	GO:0055012	ventricular cardiac muscle cell differentiation	Rxrb	IMP	MGI:MGI:1857822	Mouse	PMID:9428411
Biological Process	GO:0055012	ventricular cardiac muscle cell differentiation	Rxrb	IGI	MGI:MGI:98214	Mouse	PMID:9428411

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern